ID   A1RXD2_THEPD            Unreviewed;       241 AA.
AC   A1RXD2;
DT   06-FEB-2007, integrated into UniProtKB/TrEMBL.
DT   06-FEB-2007, sequence version 1.
DT   27-MAR-2024, entry version 93.
DE   RecName: Full=non-specific serine/threonine protein kinase {ECO:0000256|ARBA:ARBA00012513};
DE            EC=2.7.11.1 {ECO:0000256|ARBA:ARBA00012513};
GN   OrderedLocusNames=Tpen_0453 {ECO:0000313|EMBL:ABL77862.1};
OS   Thermofilum pendens (strain DSM 2475 / Hrk 5).
OC   Archaea; Thermoproteota; Thermoprotei; Thermofilales; Thermofilaceae;
OC   Thermofilum.
OX   NCBI_TaxID=368408 {ECO:0000313|EMBL:ABL77862.1, ECO:0000313|Proteomes:UP000000641};
RN   [1] {ECO:0000313|Proteomes:UP000000641}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 2475 / Hrk 5 {ECO:0000313|Proteomes:UP000000641};
RX   PubMed=18263724; DOI=10.1128/JB.01949-07;
RA   Anderson I., Rodriguez J., Susanti D., Porat I., Reich C., Ulrich L.E.,
RA   Elkins J.G., Mavromatis K., Lykidis A., Kim E., Thompson L.S., Nolan M.,
RA   Land M., Copeland A., Lapidus A., Lucas S., Detter C., Zhulin I.B.,
RA   Olsen G.J., Whitman W., Mukhopadhyay B., Bristow J., Kyrpides N.;
RT   "Genome sequence of Thermofilum pendens reveals an exceptional loss of
RT   biosynthetic pathways without genome reduction.";
RL   J. Bacteriol. 190:2957-2965(2008).
CC   -!- SIMILARITY: Belongs to the protein kinase superfamily. BUD32 family.
CC       {ECO:0000256|ARBA:ARBA00010630}.
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DR   EMBL; CP000505; ABL77862.1; -; Genomic_DNA.
DR   RefSeq; WP_011752127.1; NC_008698.1.
DR   AlphaFoldDB; A1RXD2; -.
DR   STRING; 368408.Tpen_0453; -.
DR   EnsemblBacteria; ABL77862; ABL77862; Tpen_0453.
DR   GeneID; 4601856; -.
DR   KEGG; tpe:Tpen_0453; -.
DR   eggNOG; arCOG01185; Archaea.
DR   HOGENOM; CLU_063953_2_0_2; -.
DR   Proteomes; UP000000641; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR   GO; GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR   InterPro; IPR022495; Bud32.
DR   InterPro; IPR011009; Kinase-like_dom_sf.
DR   InterPro; IPR000719; Prot_kinase_dom.
DR   InterPro; IPR008266; Tyr_kinase_AS.
DR   NCBIfam; TIGR03724; arch_bud32; 1.
DR   PANTHER; PTHR12209:SF0; EKC_KEOPS COMPLEX SUBUNIT TP53RK; 1.
DR   PANTHER; PTHR12209; NON-SPECIFIC SERINE/THREONINE PROTEIN KINASE; 1.
DR   Pfam; PF00069; Pkinase; 1.
DR   SMART; SM00220; S_TKc; 1.
DR   SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR   PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR   PROSITE; PS00109; PROTEIN_KINASE_TYR; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:ABL77862.1};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000641};
KW   Serine/threonine-protein kinase {ECO:0000313|EMBL:ABL77862.1};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679};
KW   tRNA processing {ECO:0000256|ARBA:ARBA00022694}.
FT   DOMAIN          18..241
FT                   /note="Protein kinase"
FT                   /evidence="ECO:0000259|PROSITE:PS50011"
SQ   SEQUENCE   241 AA;  27203 MW;  6F29ABD29CE7606A CRC64;
     MRAFPRDAVE RLERWLGFRA EGVLGFGAEA VIVKGELAGE KVVVKYRVPK SYRDPRLDSE
     LRRERTVLES RILSRAAMAG VNVPVPVLVY PEEGILVMTY IGGERLKDSM RGIEPGTLRN
     VFVEIGRQLG TLHSLGIVYG DLTTSNVILS PTRTPWLVDF GLGFFSNRDE DAGVDLHLFK
     RALESTHPLQ AEDLFQAFVD GYAQIRGRET AEKILAKMRE IRLRGRYVKE RRARLSRAFS
     G
//