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Protein

Replication factor C small subunit

Gene

rfcS

Organism
Thermofilum pendens (strain Hrk 5)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA.UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi44 – 518ATPUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

DNA replication

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciTPEN368408:GHSG-270-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Replication factor C small subunitUniRule annotation
Short name:
RFC small subunitUniRule annotation
Alternative name(s):
Clamp loader small subunitUniRule annotation
Gene namesi
Name:rfcSUniRule annotation
Ordered Locus Names:Tpen_0267
OrganismiThermofilum pendens (strain Hrk 5)
Taxonomic identifieri368408 [NCBI]
Taxonomic lineageiArchaeaCrenarchaeotaThermoproteiThermoprotealesThermofilaceaeThermofilum
Proteomesi
  • UP000000641 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 325325Replication factor C small subunitPRO_0000292191Add
BLAST

Interactioni

Subunit structurei

Heteromultimer composed of small subunits (RfcS) and large subunits (RfcL).UniRule annotation

Protein-protein interaction databases

STRINGi368408.Tpen_0267.

Structurei

3D structure databases

ProteinModelPortaliA1RWU7.
SMRiA1RWU7. Positions 1-321.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the activator 1 small subunits family. RfcS subfamily.UniRule annotation

Phylogenomic databases

eggNOGiarCOG00469. Archaea.
COG0470. LUCA.
HOGENOMiHOG000224155.
KOiK04801.
OMAiPFKVIFL.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
HAMAPiMF_01509. RfcS. 1 hit.
InterProiIPR003593. AAA+_ATPase.
IPR003959. ATPase_AAA_core.
IPR000641. CbxX_CfqX.
IPR008921. DNA_pol3_clamp-load_cplx_C.
IPR027417. P-loop_NTPase.
IPR023748. Rep_factor-C_ssu_arc.
IPR013748. Rep_factorC_C.
[Graphical view]
PfamiPF00004. AAA. 1 hit.
PF08542. Rep_fac_C. 1 hit.
[Graphical view]
PRINTSiPR00819. CBXCFQXSUPER.
SMARTiSM00382. AAA. 1 hit.
[Graphical view]
SUPFAMiSSF48019. SSF48019. 1 hit.
SSF52540. SSF52540. 1 hit.

Sequencei

Sequence statusi: Complete.

A1RWU7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSEELWVEKY RPRSLDEIVD QEEIVKRLKE FVKNKNMPHL LFAGPPGTGK
60 70 80 90 100
TTAALALAHD LYGESWRDNT LELNASDERG IDVIRSRIKD YARTLPIGDV
110 120 130 140 150
PFKLVILDEA DNMTGDAQQA LRRTMELFSR NTRFILIANY ASKIIEPIQS
160 170 180 190 200
RCAVFRFQPL PKGDAFQRLR WIAQQEGITV DDGALEAIWE ESQGDLRKAI
210 220 230 240 250
NTLQAASAIS RNVTEEVVYA ALGRVKPKEV REMIESALKG NLLEARDKLR
260 270 280 290 300
LLLYNYGLSG VDIIRFIHRE VLSQKSVRLD DATLAELLVL VGETNYRIVE
310 320
GSDDEIQLMA LLSKLALVSK KAAKG
Length:325
Mass (Da):36,665
Last modified:February 6, 2007 - v1
Checksum:i9BD00C15394FF8A9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000505 Genomic DNA. Translation: ABL77677.1.
RefSeqiWP_011751942.1. NC_008698.1.

Genome annotation databases

EnsemblBacteriaiABL77677; ABL77677; Tpen_0267.
GeneIDi4601685.
KEGGitpe:Tpen_0267.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000505 Genomic DNA. Translation: ABL77677.1.
RefSeqiWP_011751942.1. NC_008698.1.

3D structure databases

ProteinModelPortaliA1RWU7.
SMRiA1RWU7. Positions 1-321.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi368408.Tpen_0267.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABL77677; ABL77677; Tpen_0267.
GeneIDi4601685.
KEGGitpe:Tpen_0267.

Phylogenomic databases

eggNOGiarCOG00469. Archaea.
COG0470. LUCA.
HOGENOMiHOG000224155.
KOiK04801.
OMAiPFKVIFL.

Enzyme and pathway databases

BioCyciTPEN368408:GHSG-270-MONOMER.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
HAMAPiMF_01509. RfcS. 1 hit.
InterProiIPR003593. AAA+_ATPase.
IPR003959. ATPase_AAA_core.
IPR000641. CbxX_CfqX.
IPR008921. DNA_pol3_clamp-load_cplx_C.
IPR027417. P-loop_NTPase.
IPR023748. Rep_factor-C_ssu_arc.
IPR013748. Rep_factorC_C.
[Graphical view]
PfamiPF00004. AAA. 1 hit.
PF08542. Rep_fac_C. 1 hit.
[Graphical view]
PRINTSiPR00819. CBXCFQXSUPER.
SMARTiSM00382. AAA. 1 hit.
[Graphical view]
SUPFAMiSSF48019. SSF48019. 1 hit.
SSF52540. SSF52540. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiRFCS_THEPD
AccessioniPrimary (citable) accession number: A1RWU7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 26, 2007
Last sequence update: February 6, 2007
Last modified: September 7, 2016
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.