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A1RVD1 (AROC_PYRIL) Reviewed, UniProtKB/Swiss-Prot

Last modified November 16, 2011. Version 33. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Chorismate synthase
EC=4.2.3.5
Alternative name(s):
5-enolpyruvylshikimate-3-phosphate phospholyase
Gene names
Name:aroC
Ordered Locus Names:Pisl_1763
OrganismPyrobaculum islandicum (strain DSM 4184 / JCM 9189) [Complete proteome] [HAMAP]
Taxonomic identifier384616 [NCBI]
Taxonomic lineageArchaea › Crenarchaeota › Thermoprotei › Thermoproteales › Thermoproteaceae › Pyrobaculum

Protein attributes

Sequence length365 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

5-O-(1-carboxyvinyl)-3-phosphoshikimate = chorismate + phosphate. HAMAP MF_00300

Cofactor

Reduced flavin By similarity. HAMAP MF_00300

Pathway

Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 7/7. HAMAP MF_00300

Sequence similarities

Belongs to the chorismate synthase family.

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Aromatic amino acid biosynthesis
   Molecular functionLyase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processaromatic amino acid family biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular functionchorismate synthase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 365365Chorismate synthase HAMAP MF_00300
PRO_0000322438

Sequences

Sequence LengthMass (Da)Tools
A1RVD1 [UniParc].

Last modified February 6, 2007. Version 1.
Checksum: F43E9938A86807DB

FASTA36539,614
        10         20         30         40         50         60 
MNTFGREFRI TTFGESHGKA IGVVIDGVPA GLELTEEDIK RELERRMFCH IPVLNPRCEP 

        70         80         90        100        110        120 
EEVEILSGVK EGYTQGTPIA VVIWNRRVIS SYYEELWMKP RPGHADFAYY LKYGRYYDHR 

       130        140        150        160        170        180 
GGGRASGRTT AAVVAAGAVA KKILALAGAE VAGHIVELGG VEINASYTYE DVKKSWERPL 

       190        200        210        220        230        240 
PVVDQQALDK MLEKIQEAAA RGDSIGGGVE VWAVGVPPGL GEPHFGKIKA DIAAAAFSIP 

       250        260        270        280        290        300 
GAIALDWGMG RALAKMWGSE ANDPITVANG RPTLATNKIG GVLGGITVGT PIYFRVWFKP 

       310        320        330        340        350        360 
TPSVRKPQQT VDLAKMEPTT IEFKGRYDVS IVPKALVALE AITAVTLADH LLRAGLIRRD 


KPLEK

« Hide

References

[1]"Complete sequence of Pyrobaculum islandicum DSM 4184."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Meincke L., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J., Larimer F., Land M. expand/collapse author list , Hauser L., Kyrpides N., Mikhailova N., Lowe T., Richardson P.
Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DSM 4184 / JCM 9189.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000504 Genomic DNA. Translation: ABL88913.1.
RefSeqYP_931256.1. NC_008701.1.

3D structure databases

ProteinModelPortalA1RVD1.
ModBaseSearch...

Protein-protein interaction databases

STRINGA1RVD1.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4617869.
GenomeReviewsGene locus Pisl_1763 in contig CP000504_GR.
KEGGpis:Pisl_1763.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGarNOG04618.
HOGENOMHBG292336.
OMASRFTTQR.
ProtClustDBPRK05382.

Enzyme and pathway databases

BioCycPISL384616:PISL_1763-MONOMER.

Family and domain databases

HAMAPMF_00300. Chorismate_synth.
[Tree]
InterProIPR000453. Chorismate_synth.
IPR020541. Chorismate_synthase_CS.
[Graphical view]
KOK01736.
PANTHERPTHR21085. Chorismate_synth. 1 hit.
PfamPF01264. Chorismate_synt. 1 hit.
[Graphical view]
PIRSFPIRSF001456. Chorismate_synth. 1 hit.
SUPFAMSSF103263. Chorismate_synth. 1 hit.
TIGRFAMsTIGR00033. AroC. 1 hit.
PROSITEPS00787. CHORISMATE_SYNTHASE_1. 1 hit.
PS00788. CHORISMATE_SYNTHASE_2. 1 hit.
PS00789. CHORISMATE_SYNTHASE_3. False negative.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameAROC_PYRIL
AccessionPrimary (citable) accession number: A1RVD1
Entry history
Integrated into UniProtKB/Swiss-Prot: February 26, 2008
Last sequence update: February 6, 2007
Last modified: November 16, 2011
This is version 33 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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