Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

A1RV37

- TF2B_PYRIL

UniProt

A1RV37 - TF2B_PYRIL

Protein

Transcription initiation factor IIB

Gene

tfb

Organism
Pyrobaculum islandicum (strain DSM 4184 / JCM 9189)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 56 (01 Oct 2014)
      Sequence version 1 (06 Feb 2007)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).UniRule annotation

    Cofactori

    Binds 1 zinc ion per subunit.UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Metal bindingi37 – 371ZincUniRule annotation
    Metal bindingi40 – 401ZincUniRule annotation
    Metal bindingi56 – 561ZincUniRule annotation
    Metal bindingi59 – 591ZincUniRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Zinc fingeri33 – 6432TFIIB-typeUniRule annotationAdd
    BLAST

    GO - Molecular functioni

    1. sequence-specific DNA binding transcription factor activity Source: UniProtKB-HAMAP
    2. zinc ion binding Source: UniProtKB-HAMAP

    GO - Biological processi

    1. DNA-templated transcription, initiation Source: UniProtKB-HAMAP

    Keywords - Biological processi

    Transcription, Transcription regulation

    Keywords - Ligandi

    Metal-binding, Zinc

    Enzyme and pathway databases

    BioCyciPISL384616:GC8H-1702-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Transcription initiation factor IIBUniRule annotation
    Short name:
    TFIIBUniRule annotation
    Gene namesi
    Name:tfbUniRule annotation
    Ordered Locus Names:Pisl_1667
    OrganismiPyrobaculum islandicum (strain DSM 4184 / JCM 9189)
    Taxonomic identifieri384616 [NCBI]
    Taxonomic lineageiArchaeaCrenarchaeotaThermoproteiThermoprotealesThermoproteaceaePyrobaculum
    ProteomesiUP000002595: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 333333Transcription initiation factor IIBPRO_1000080116Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi384616.Pisl_1667.

    Structurei

    3D structure databases

    ProteinModelPortaliA1RV37.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Repeati149 – 232841Add
    BLAST
    Repeati243 – 324822Add
    BLAST

    Sequence similaritiesi

    Belongs to the TFIIB family.UniRule annotation
    Contains 1 TFIIB-type zinc finger.UniRule annotation

    Zinc finger

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Zinc fingeri33 – 6432TFIIB-typeUniRule annotationAdd
    BLAST

    Keywords - Domaini

    Repeat, Zinc-finger

    Phylogenomic databases

    eggNOGiCOG1405.
    HOGENOMiHOG000108633.
    KOiK03124.
    OMAiCGNDKFV.

    Family and domain databases

    Gene3Di1.10.472.10. 2 hits.
    HAMAPiMF_00383. TF2B_arch.
    InterProiIPR013763. Cyclin-like.
    IPR000812. TFIIB.
    IPR023484. TFIIB_arc.
    IPR023486. TFIIB_CS.
    IPR013150. TFIIB_cyclin.
    IPR013137. Znf_TFIIB.
    [Graphical view]
    PANTHERiPTHR11618. PTHR11618. 1 hit.
    PfamiPF08271. TF_Zn_Ribbon. 1 hit.
    PF00382. TFIIB. 2 hits.
    [Graphical view]
    PRINTSiPR00685. TIFACTORIIB.
    SMARTiSM00385. CYCLIN. 2 hits.
    [Graphical view]
    SUPFAMiSSF47954. SSF47954. 2 hits.
    PROSITEiPS00782. TFIIB. 2 hits.
    PS51134. ZF_TFIIB. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    A1RV37-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSSSSPTSSG KPLKLRIDRD NEGYLSLVTD TGEVYRCPIC GNDRFVYNYE    50
    RGEIVCIVCG AVVQEQLLDL GPEWRAFTSE EKGQRARTGA PLTRLISEAL 100
    TTVIDWRDKD VSGKELDIKR KLEVIRLRKW QTRARVQTSY ERNFIQAAQE 150
    LERLRSSMGV PRPCVEQALE IYRQALEKEL VRGRSVEAMA AAALYMACRM 200
    MKMPRPLDEL VRYTKASRRE VARCYRLLLR ELNVKVPISD PVLYISRIAE 250
    QLKLSGEVVK TAIEILQKAK KAGITAGKDP AGLAAAAVYI ASLLHGDNRT 300
    QKDFAVAAGV TEVTVRNRYK ELAKTLNIKV PVK 333
    Length:333
    Mass (Da):37,475
    Last modified:February 6, 2007 - v1
    Checksum:i47826C971CAC2CCC
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000504 Genomic DNA. Translation: ABL88819.1.
    RefSeqiWP_011763394.1. NC_008701.1.
    YP_931162.1. NC_008701.1.

    Genome annotation databases

    EnsemblBacteriaiABL88819; ABL88819; Pisl_1667.
    GeneIDi4617859.
    KEGGipis:Pisl_1667.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000504 Genomic DNA. Translation: ABL88819.1 .
    RefSeqi WP_011763394.1. NC_008701.1.
    YP_931162.1. NC_008701.1.

    3D structure databases

    ProteinModelPortali A1RV37.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 384616.Pisl_1667.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABL88819 ; ABL88819 ; Pisl_1667 .
    GeneIDi 4617859.
    KEGGi pis:Pisl_1667.

    Phylogenomic databases

    eggNOGi COG1405.
    HOGENOMi HOG000108633.
    KOi K03124.
    OMAi CGNDKFV.

    Enzyme and pathway databases

    BioCyci PISL384616:GC8H-1702-MONOMER.

    Family and domain databases

    Gene3Di 1.10.472.10. 2 hits.
    HAMAPi MF_00383. TF2B_arch.
    InterProi IPR013763. Cyclin-like.
    IPR000812. TFIIB.
    IPR023484. TFIIB_arc.
    IPR023486. TFIIB_CS.
    IPR013150. TFIIB_cyclin.
    IPR013137. Znf_TFIIB.
    [Graphical view ]
    PANTHERi PTHR11618. PTHR11618. 1 hit.
    Pfami PF08271. TF_Zn_Ribbon. 1 hit.
    PF00382. TFIIB. 2 hits.
    [Graphical view ]
    PRINTSi PR00685. TIFACTORIIB.
    SMARTi SM00385. CYCLIN. 2 hits.
    [Graphical view ]
    SUPFAMi SSF47954. SSF47954. 2 hits.
    PROSITEi PS00782. TFIIB. 2 hits.
    PS51134. ZF_TFIIB. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Complete sequence of Pyrobaculum islandicum DSM 4184."
      Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Meincke L., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J., Larimer F., Land M.
      , Hauser L., Kyrpides N., Mikhailova N., Lowe T., Richardson P.
      Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: DSM 4184 / JCM 9189.

    Entry informationi

    Entry nameiTF2B_PYRIL
    AccessioniPrimary (citable) accession number: A1RV37
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 20, 2008
    Last sequence update: February 6, 2007
    Last modified: October 1, 2014
    This is version 56 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3