A1RTD5 (APGM_PYRIL) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
2,3-bisphosphoglycerate-independent phosphoglycerate mutase
Short name=BPG-independent PGAM
Short name=Phosphoglyceromutase
Short name=aPGAM
EC=5.4.2.1

Gene names

Name:	apgM
Ordered Locus Names:	Pisl_1043

Organism

Pyrobaculum islandicum (strain DSM 4184 / JCM 9189) [Complete proteome] [HAMAP]

Taxonomic identifier

384616 [NCBI]

Taxonomic lineage

Archaea › Crenarchaeota › Thermoprotei › Thermoproteales › Thermoproteaceae › Pyrobaculum

Protein attributes

Sequence length	411 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate By similarity. HAMAP MF_01402_A
Catalytic activity	2-phospho-D-glycerate = 3-phospho-D-glycerate. HAMAP MF_01402_A
Pathway	Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 3/5. HAMAP MF_01402_A
Sequence similarities	Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.

Ontologies

Keywords
Biological process	Glycolysis
Molecular function	Isomerase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycolysis Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	metal ion binding Inferred from electronic annotation. Source: InterPro phosphoglycerate mutase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 411	411	2,3-bisphosphoglycerate-independent phosphoglycerate mutase HAMAP MF_01402_A		PRO_1000087370

Sequences

	Sequence		Length	Mass (Da)
	A1RTD5 [UniParc]. Last modified February 6, 2007. Version 1. Checksum: 8E6000236C46E1FF	FASTA	411	44,991
	10 20 30 40 50 60 MPSVFWILFD GGGDRPVGGR TPFHTAFKPT IDYLTSLGSC GILDPIAPGV RPGSDTAHLA 70 80 90 100 110 120 LFGYDPYKYY TGRGAFEALG AGLELKPGDV AFRTNLATID DNGMVLDRRA GRYITPEEVE 130 140 150 160 170 180 AVENLMANIA EDIKRKYGVE IIYKSTVEHR GVLVLRGSVS HKVSDTDPHK VGAKLLESRP 190 200 210 220 230 240 LENSKEAVLT AEVINEVTKR FSEVAKDLEI NRKRRLEGRL PINAILLRGG GYMPQIEPVR 250 260 270 280 290 300 ERYNIKAAAI AGVALIRGVA RAVGMDVYTA RGLGGTKDDM FDEAVRLAVE LMGRYDLVFL 310 320 330 340 350 360 HVKGTDSASH DGDFKGKVSV IERLDKALTP YLDKLLNNYV VITSDHATPI SIKEHTGESV 370 380 390 400 410 PILLYGPDVV TDDVSKFSEL TCWRGALGRI RGIDVMPILG SYLALTEKFG E

References

[1]

"Complete sequence of Pyrobaculum islandicum DSM 4184." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Meincke L., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J., Larimer F., Land M. , Hauser L., Kyrpides N., Mikhailova N., Lowe T., Richardson P. Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: DSM 4184 / JCM 9189.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000504 Genomic DNA. Translation: ABL88217.1.
RefSeq	YP_930560.1. NC_008701.1.
3D structure databases
ProteinModelPortal	A1RTD5.
ModBase	Search...
Protein-protein interaction databases
STRING	A1RTD5.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4617997.
GenomeReviews	Gene locus Pisl_1043 in contig CP000504_GR.
KEGG	pis:Pisl_1043.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	arNOG04733.
HOGENOM	HBG463247.
ProtClustDB	PRK04024.
Enzyme and pathway databases
BioCyc	PISL384616:PISL_1043-MONOMER.
Family and domain databases
HAMAP	MF_01402_A. ApgM_A. [Tree]
InterPro	IPR017849. Alkaline_Pase-like_a/b/a. IPR017850. Alkaline_phosphatase_core. IPR023665. ApgAM. IPR004456. BisP-indep_Pglycerate_Mutase. IPR006124. Metalloenzyme. [Graphical view]
Gene3D	G3DSA:3.40.720.10. Alk_phosphtse. 2 hits.
KO	K15635.
Pfam	PF01676. Metalloenzyme. 1 hit. PF10143. PhosphMutase. 1 hit. [Graphical view]
PIRSF	PIRSF006392. IPGAM_arch. 1 hit.
SUPFAM	SSF53649. Alkaline_phosphatase_core. 1 hit.
TIGRFAMs	TIGR00306. ApgM. 1 hit.
ProtoNet	Search...

Entry information

Entry name

APGM_PYRIL

Accession

Primary (citable) accession number: A1RTD5

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 20, 2008
Last sequence update:	February 6, 2007
Last modified:	January 25, 2012
This is version 38 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program