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Protein

TATA-box-binding protein

Gene

tbp

Organism
Pyrobaculum islandicum (strain DSM 4184 / JCM 9189 / GEO3)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
TATA-box-binding proteinUniRule annotation
Alternative name(s):
Box A-binding proteinUniRule annotation
Short name:
BAPUniRule annotation
TATA sequence-binding proteinUniRule annotation
Short name:
TBPUniRule annotation
TATA-box factorUniRule annotation
Gene namesi
Name:tbpUniRule annotation
Ordered Locus Names:Pisl_0807
OrganismiPyrobaculum islandicum (strain DSM 4184 / JCM 9189 / GEO3)
Taxonomic identifieri384616 [NCBI]
Taxonomic lineageiArchaeaCrenarchaeotaThermoproteiThermoprotealesThermoproteaceaePyrobaculum
Proteomesi
  • UP000002595 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000498871 – 199TATA-box-binding proteinAdd BLAST199

Interactioni

Protein-protein interaction databases

STRINGi384616.Pisl_0807.

Structurei

3D structure databases

ProteinModelPortaliA1RSQ1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati10 – 861Add BLAST77
Repeati101 – 1772Add BLAST77

Sequence similaritiesi

Belongs to the TBP family.UniRule annotation

Keywords - Domaini

Repeat

Phylogenomic databases

eggNOGiarCOG01764. Archaea.
COG2101. LUCA.
HOGENOMiHOG000105163.
KOiK03120.
OMAiTLPNCEY.

Family and domain databases

CDDicd04518. TBP_archaea. 1 hit.
Gene3Di3.30.310.10. 2 hits.
HAMAPiMF_00408. TATA_bind_prot_arch. 1 hit.
InterProiIPR012295. Beta2_adaptin/TBP_C_dom.
IPR000814. TBP.
IPR033711. TBP_archaea.
IPR030491. TBP_CS.
[Graphical view]
PANTHERiPTHR10126. PTHR10126. 1 hit.
PfamiPF00352. TBP. 2 hits.
[Graphical view]
PRINTSiPR00686. TIFACTORIID.
PROSITEiPS00351. TFIID. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A1RSQ1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MESGGPTYRI ENIVATVNLG VELDLEKLAE RLAMAEYNPD QFPGLILRLT
60 70 80 90 100
KPRISALIFR TGKMVCTGAK NEEDLKNAVR ALVKLLRDHG AEVPFDPEVQ
110 120 130 140 150
VQNIVASGNL HAEVDLEQAV LMLENAMYEP EQFPGLIYRM SSPRVVMLIF
160 170 180 190
GSGKIVCTGA KSERDVATAV QKLYNQLKDL GVLYIEEGGG EEEEELEEL
Length:199
Mass (Da):22,034
Last modified:February 6, 2007 - v1
Checksum:i8575E976772C191A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000504 Genomic DNA. Translation: ABL87983.1.
RefSeqiWP_011762559.1. NC_008701.1.

Genome annotation databases

EnsemblBacteriaiABL87983; ABL87983; Pisl_0807.
GeneIDi4617268.
KEGGipis:Pisl_0807.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000504 Genomic DNA. Translation: ABL87983.1.
RefSeqiWP_011762559.1. NC_008701.1.

3D structure databases

ProteinModelPortaliA1RSQ1.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi384616.Pisl_0807.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABL87983; ABL87983; Pisl_0807.
GeneIDi4617268.
KEGGipis:Pisl_0807.

Phylogenomic databases

eggNOGiarCOG01764. Archaea.
COG2101. LUCA.
HOGENOMiHOG000105163.
KOiK03120.
OMAiTLPNCEY.

Family and domain databases

CDDicd04518. TBP_archaea. 1 hit.
Gene3Di3.30.310.10. 2 hits.
HAMAPiMF_00408. TATA_bind_prot_arch. 1 hit.
InterProiIPR012295. Beta2_adaptin/TBP_C_dom.
IPR000814. TBP.
IPR033711. TBP_archaea.
IPR030491. TBP_CS.
[Graphical view]
PANTHERiPTHR10126. PTHR10126. 1 hit.
PfamiPF00352. TBP. 2 hits.
[Graphical view]
PRINTSiPR00686. TIFACTORIID.
PROSITEiPS00351. TFIID. 2 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiTBP_PYRIL
AccessioniPrimary (citable) accession number: A1RSQ1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: February 6, 2007
Last modified: November 2, 2016
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.