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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Pyrobaculum islandicum (strain DSM 4184 / JCM 9189)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

  1. arginine-tRNA ligase activity Source: UniProtKB-HAMAP
  2. ATP binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. arginyl-tRNA aminoacylation Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Aminoacyl-tRNA synthetase, Ligase

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciPISL384616:GC8H-602-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)
Alternative name(s):
Arginyl-tRNA synthetaseUniRule annotation
Short name:
ArgRSUniRule annotation
Gene namesi
Name:argSUniRule annotation
Ordered Locus Names:Pisl_0586
OrganismiPyrobaculum islandicum (strain DSM 4184 / JCM 9189)
Taxonomic identifieri384616 [NCBI]
Taxonomic lineageiArchaeaCrenarchaeotaThermoproteiThermoprotealesThermoproteaceaePyrobaculum
ProteomesiUP000002595: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 632632Arginine--tRNA ligasePRO_1000018098Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi384616.Pisl_0586.

Structurei

3D structure databases

ProteinModelPortaliA1RS32.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi120 – 13011"HIGH" regionAdd
BLAST

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0018.
HOGENOMiHOG000247213.
KOiK01887.
OMAiACNKNEP.

Family and domain databases

Gene3Di1.10.730.10. 1 hit.
3.40.50.620. 2 hits.
HAMAPiMF_00123. Arg_tRNA_synth.
InterProiIPR001278. Arg-tRNA-ligase.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERiPTHR11956. PTHR11956. 1 hit.
PfamiPF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 2 hits.
[Graphical view]
PRINTSiPR01038. TRNASYNTHARG.
SMARTiSM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMiSSF47323. SSF47323. 1 hit.
TIGRFAMsiTIGR00456. argS. 1 hit.

Sequencei

Sequence statusi: Complete.

A1RS32-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDPLKPPREE FEKFVAEVAY AIGIGEVPEI ERSKRFGYFS AKFHKYRVDA
60 70 80 90 100
GKLKETVDSL KSRQFKYLTS ISVDGLYLNV DLAVEKVAEL TFRAVAEMGD
110 120 130 140 150
KYGFTDECKI GSFLVEHTSA NPIHPLHIGH GRNAILGDSL VRLLRFCGNV
160 170 180 190 200
VQSHFYVDDC GVQVMYAAIG YNVVKKYVDE VLKRTKPDVV IGAIYSAVNA
210 220 230 240 250
IAEINRLKKE LEKEKDDEKR REIINEIDSW VSVLKRLIDT EGEVINKLVE
260 270 280 290 300
VLGQRNIVEE AAELNKRYET GDPEVKKIVR EVVELVLKGQ RETLARLGIE
310 320 330 340 350
LDSWDYESDI AVWSGEATRV VSELRRRWPQ YIDDRGGAVV FRADKFVEDF
360 370 380 390 400
KLWDVLDLPK FIPPVTLTRS DGTTLYVTRD VAYALWQARR GFDKVIRVIS
410 420 430 440 450
TEQTHEQAHV RIILYALGYE DVAKKLIHYA YEMVNLPGMK MSARRGQYIS
460 470 480 490 500
LDEILDEAVE RSADLVKEKN PEIAGIIAER VGVGSVRYAF LSTSPRKPIE
510 520 530 540 550
FKWETVLNMR QNSGPFLQYT YVRAYSILEK AQEIDLKKVA IPKEILPEER
560 570 580 590 600
ELILKVAEWP SVVREATRAL RPDYVAEFLD GLALIFNSYY EKAPVLKTEE
610 620 630
PVRSFRLALV NSVKTVLAAG FYILGIPTLT KM
Length:632
Mass (Da):72,117
Last modified:February 6, 2007 - v1
Checksum:i3A481240A6BC3E5F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000504 Genomic DNA. Translation: ABL87764.1.
RefSeqiYP_930107.1. NC_008701.1.

Genome annotation databases

EnsemblBacteriaiABL87764; ABL87764; Pisl_0586.
GeneIDi4616557.
KEGGipis:Pisl_0586.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000504 Genomic DNA. Translation: ABL87764.1.
RefSeqiYP_930107.1. NC_008701.1.

3D structure databases

ProteinModelPortaliA1RS32.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi384616.Pisl_0586.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABL87764; ABL87764; Pisl_0586.
GeneIDi4616557.
KEGGipis:Pisl_0586.

Phylogenomic databases

eggNOGiCOG0018.
HOGENOMiHOG000247213.
KOiK01887.
OMAiACNKNEP.

Enzyme and pathway databases

BioCyciPISL384616:GC8H-602-MONOMER.

Family and domain databases

Gene3Di1.10.730.10. 1 hit.
3.40.50.620. 2 hits.
HAMAPiMF_00123. Arg_tRNA_synth.
InterProiIPR001278. Arg-tRNA-ligase.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERiPTHR11956. PTHR11956. 1 hit.
PfamiPF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 2 hits.
[Graphical view]
PRINTSiPR01038. TRNASYNTHARG.
SMARTiSM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMiSSF47323. SSF47323. 1 hit.
TIGRFAMsiTIGR00456. argS. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Complete sequence of Pyrobaculum islandicum DSM 4184."
    Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Meincke L., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J., Larimer F., Land M.
    , Hauser L., Kyrpides N., Mikhailova N., Lowe T., Richardson P.
    Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 4184 / JCM 9189.

Entry informationi

Entry nameiSYR_PYRIL
AccessioniPrimary (citable) accession number: A1RS32
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: February 6, 2007
Last modified: March 4, 2015
This is version 55 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.