A1RQ03 (RLMF_SHESW) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Ribosomal RNA large subunit methyltransferase F
EC=2.1.1.181

Alternative name(s):
23S rRNA mA1618 methyltransferase
rRNA adenine N-6-methyltransferase

Gene names

Name:	rlmF
Ordered Locus Names:	Sputw3181_3944

Organism

Shewanella sp. (strain W3-18-1) [Complete proteome] [HAMAP]

Taxonomic identifier

351745 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Alteromonadales › Shewanellaceae › Shewanella

Protein attributes

Sequence length	357 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Specifically methylates the adenine in position 1618 of 23S rRNA By similarity. HAMAP MF_01848
Catalytic activity	S-adenosyl-L-methionine + adenine(1618) in 23S rRNA = S-adenosyl-L-homocysteine + rRNA containing N(6)-methyladenine(1618) in 23S rRNA. HAMAP MF_01848
Subcellular location	Cytoplasm Potential HAMAP MF_01848.
Sequence similarities	Belongs to the methyltransferase superfamily. METTL16/rlmF family.

Ontologies

Keywords
Biological process	rRNA processing
Cellular component	Cytoplasm
Ligand	S-adenosyl-L-methionine
Molecular function	Methyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	rRNA (adenine-N6-)-methyltransferase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 357	357	Ribosomal RNA large subunit methyltransferase F HAMAP MF_01848		PRO_0000349965

Sequences

	Sequence		Length	Mass (Da)
	A1RQ03 [UniParc]. Last modified February 6, 2007. Version 1. Checksum: BFD1A92ED24C8ED4	FASTA	357	39,438
	10 20 30 40 50 60 MPKPPRSTQI LSCNAPNGKP KTQHPSARAK VKRTPVNTRS IAEIKKALHP RNVHINGYDF 70 80 90 100 110 120 NALIKAFPRL NAFVRPTSFG GLSIDFADPE AVKTLNTALL KHHYGIDFWD IPKGALCPPI 130 140 150 160 170 180 PGRVDYLHYL ADLLAEGDHH LVMDRVSVLD IGTGANGIYP ILGCQVFGWH FVASDINSIS 190 200 210 220 230 240 LANVQGIIAQ NPALHGRLNL RLQGDESAIF KGVIQPQERF ELTLCNPPFH ASLAEAAEGS 250 260 270 280 290 300 LRKVRNLQLN RGRTAKPVAK LNFGGQGAEL WCQGGEPQFL ATMIDESQAF ADQCLWFTSL 310 320 330 340 350 VSKKENLKPC YQALAKLAVD TVKTIEMQQG NKMTRILAWS FQSAAKRKIW RNAHLSD

References

[1]

"Complete sequence of Shewanella sp. W3-18-1." US DOE Joint Genome Institute Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M. , Hauser L., Kyrpides N., Lykidis A., Tiedje J., Richardson P. Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: W3-18-1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000503 Genomic DNA. Translation: ABM26748.1.
RefSeq	YP_965302.1. NC_008750.1.
3D structure databases
ProteinModelPortal	A1RQ03.
ModBase	Search...
Protein-protein interaction databases
STRING	A1RQ03.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4661330.
GenomeReviews	Gene locus Sputw3181_3944 in contig CP000503_GR.
KEGG	shw:Sputw3181_3944.
PATRIC	23601860. VBISheSp103602_4132.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG3129.
HOGENOM	HBG747880.
OMA	DFANPEA.
ProtClustDB	PRK11727.
Family and domain databases
HAMAP	MF_01848. 23SrRNA_methyltr_F. [Tree]
InterPro	IPR016909. rRNA_lsu_methyltransferase_F. IPR010286. SAM-Mtase_prd. [Graphical view]
KO	K06970.
PANTHER	PTHR13393. DUF890. 1 hit.
Pfam	PF05971. Methyltransf_10. 1 hit. [Graphical view]
PIRSF	PIRSF029038. Mtase_YbiN_prd. 1 hit.
ProtoNet	Search...

Entry information

Entry name

RLMF_SHESW

Accession

Primary (citable) accession number: A1RQ03

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 2, 2008
Last sequence update:	February 6, 2007
Last modified:	January 25, 2012
This is version 31 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program