Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

A1RLL4

- LPXB_SHESW

UniProt

A1RLL4 - LPXB_SHESW

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Lipid-A-disaccharide synthase

Gene

lpxB

Organism
Shewanella sp. (strain W3-18-1)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.UniRule annotation

Catalytic activityi

UDP-2,3-bis(3-hydroxytetradecanoyl)glucosamine + 2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate = UDP + 2,3-bis(3-hydroxytetradecanoyl)-D-glucosaminyl-1,6-beta-D-2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. lipid-A-disaccharide synthase activity Source: UniProtKB-EC

GO - Biological processi

  1. lipid A biosynthetic process Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Glycosyltransferase, Transferase

Keywords - Biological processi

Lipid A biosynthesis, Lipid biosynthesis, Lipid metabolism

Enzyme and pathway databases

BioCyciSSP351745:GCOY-2839-MONOMER.
UniPathwayiUPA00359; UER00481.

Protein family/group databases

CAZyiGT19. Glycosyltransferase Family 19.

Names & Taxonomyi

Protein namesi
Recommended name:
Lipid-A-disaccharide synthaseUniRule annotation (EC:2.4.1.182UniRule annotation)
Gene namesi
Name:lpxBUniRule annotation
Ordered Locus Names:Sputw3181_2742
OrganismiShewanella sp. (strain W3-18-1)
Taxonomic identifieri351745 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesShewanellaceaeShewanella
ProteomesiUP000002597: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 384384Lipid-A-disaccharide synthasePRO_1000049421Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi351745.Sputw3181_2742.

Structurei

3D structure databases

ProteinModelPortaliA1RLL4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the LpxB family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0763.
HOGENOMiHOG000018003.
KOiK00748.
OMAiVSPITYR.
OrthoDBiEOG6FBWZR.

Family and domain databases

HAMAPiMF_00392. LpxB.
InterProiIPR003835. Glyco_trans_19.
[Graphical view]
PfamiPF02684. LpxB. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00215. lpxB. 1 hit.

Sequencei

Sequence statusi: Complete.

A1RLL4-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSKKSQLVFA MVAGELSGDI LGAGLMAALQ KSHPDARFVG IGGPRMEALG
60 70 80 90 100
FESLFAMEEL AVMGIVEVLS RLPRLLKVRA SLIKDITALK PDCFIGIDAP
110 120 130 140 150
DFNIGLELKL KARGIKTVHY VSPSVWAWRP KRIFKIAKAT HMVLSLLPFE
160 170 180 190 200
KAFYDKHQVP CTFVGHTLAD DIPLRSDKAA ARQLLELDAD AEYLAILPGS
210 220 230 240 250
RGGELKQLAE PFVKAALLIK ENFPDIRFVT PLVNQKRRDQ FEQALKDHAP
260 270 280 290 300
DLEIHMVEGK SREVMTAADG ILLASGTATL EAMLVKRPMV VAYRVSPLTY
310 320 330 340 350
RIAKSMMQVN RFSLPNLLAG KDVVPELIQD DCTPEKIAAA VTVELNRDFA
360 370 380
PLNAEFERLH QMLRCDASQK AADAVMRLVE TKEG
Length:384
Mass (Da):42,409
Last modified:February 6, 2007 - v1
Checksum:iB746AF9CC8C68D25
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000503 Genomic DNA. Translation: ABM25559.1.
RefSeqiYP_964113.1. NC_008750.1.

Genome annotation databases

EnsemblBacteriaiABM25559; ABM25559; Sputw3181_2742.
GeneIDi4661059.
KEGGishw:Sputw3181_2742.
PATRICi23599281. VBISheSp103602_2865.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000503 Genomic DNA. Translation: ABM25559.1 .
RefSeqi YP_964113.1. NC_008750.1.

3D structure databases

ProteinModelPortali A1RLL4.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 351745.Sputw3181_2742.

Protein family/group databases

CAZyi GT19. Glycosyltransferase Family 19.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABM25559 ; ABM25559 ; Sputw3181_2742 .
GeneIDi 4661059.
KEGGi shw:Sputw3181_2742.
PATRICi 23599281. VBISheSp103602_2865.

Phylogenomic databases

eggNOGi COG0763.
HOGENOMi HOG000018003.
KOi K00748.
OMAi VSPITYR.
OrthoDBi EOG6FBWZR.

Enzyme and pathway databases

UniPathwayi UPA00359 ; UER00481 .
BioCyci SSP351745:GCOY-2839-MONOMER.

Family and domain databases

HAMAPi MF_00392. LpxB.
InterProi IPR003835. Glyco_trans_19.
[Graphical view ]
Pfami PF02684. LpxB. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR00215. lpxB. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: W3-18-1.

Entry informationi

Entry nameiLPXB_SHESW
AccessioniPrimary (citable) accession number: A1RLL4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: February 6, 2007
Last modified: October 1, 2014
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3