SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

A1RL10

- CDD_SHESW

UniProt

A1RL10 - CDD_SHESW

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Cytidine deaminase

Gene
cdd, Sputw3181_2531
Organism
Shewanella sp. (strain W3-18-1)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis By similarity.UniRule annotation

Catalytic activityi

Cytidine + H2O = uridine + NH3.UniRule annotation
2'deoxycytidine + H2O = 2'-deoxyuridine + NH3.UniRule annotation

Cofactori

Binds 1 zinc ion By similarity.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi101 – 1011Zinc; catalytic By similarity
Active sitei103 – 1031Proton donor By similarity
Metal bindingi128 – 1281Zinc; catalytic By similarity
Metal bindingi131 – 1311Zinc; catalytic By similarity

GO - Molecular functioni

  1. cytidine deaminase activity Source: UniProtKB-HAMAP
  2. zinc ion binding Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Ligandi

Metal-binding, Zinc

Enzyme and pathway databases

BioCyciSSP351745:GCOY-2625-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Cytidine deaminase (EC:3.5.4.5)
Alternative name(s):
Cytidine aminohydrolase
Short name:
CDA
Gene namesi
Name:cdd
Ordered Locus Names:Sputw3181_2531
OrganismiShewanella sp. (strain W3-18-1)
Taxonomic identifieri351745 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesShewanellaceaeShewanella
ProteomesiUP000002597: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 296296Cytidine deaminaseUniRule annotationPRO_1000068968Add
BLAST

Interactioni

Subunit structurei

Homodimer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi351745.Sputw3181_2531.

Structurei

3D structure databases

ProteinModelPortaliA1RL10.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini48 – 13891CMP/dCMP deaminase zinc-bindingAdd
BLAST

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni88 – 903Substrate binding By similarity

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0295.
HOGENOMiHOG000218617.
KOiK01489.
OMAiNRSHAPY.
OrthoDBiEOG6XDH25.

Family and domain databases

HAMAPiMF_01558. Cyt_deam.
InterProiIPR016192. APOBEC/CMP_deaminase_Zn-bd.
IPR002125. CMP_dCMP_Zn-bd.
IPR013171. Cyd/dCyd_deaminase_Zn-bd.
IPR006263. Cyt_deam_dimer.
IPR016193. Cytidine_deaminase-like.
IPR020797. Cytidine_deaminase_bacteria.
[Graphical view]
PfamiPF00383. dCMP_cyt_deam_1. 1 hit.
PF08211. dCMP_cyt_deam_2. 1 hit.
[Graphical view]
PIRSFiPIRSF006334. Cdd_plus_pseudo. 1 hit.
SUPFAMiSSF53927. SSF53927. 2 hits.
PROSITEiPS00903. CYT_DCMP_DEAMINASES. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A1RL10-1 [UniParc]FASTAAdd to Basket

« Hide

MQDRFIRSIT QLPLPLADAL IPLLHQNFAG HIDAMQLAKL TLASKMTEAE    50
VLLALLPIAA ALAKPPISEF YVGAIAKGKS GDIYMGANLE LPGEALFHSV 100
HAEQSAISHA WLSGESQIVD IIVNASPCGH CRQFMNELVD GANITIHLPA 150
QESHSLAYYL PYAFGPKDLN VVSPLLAKQQ TEFVLDSSDP MIIEGLDHAG 200
LSYAPYTQSF AAVVLETHDG ATYCGRYAEN AAFNPSMLPM QMALSNLTRH 250
NREFSDIRRA VLIESSQGKI SLVGATMDAL HTIAAVELEH IVVDPV 296
Length:296
Mass (Da):32,023
Last modified:February 6, 2007 - v1
Checksum:i74D9F7F0192A0AE6
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000503 Genomic DNA. Translation: ABM25355.1.
RefSeqiYP_963909.1. NC_008750.1.

Genome annotation databases

EnsemblBacteriaiABM25355; ABM25355; Sputw3181_2531.
GeneIDi4659819.
KEGGishw:Sputw3181_2531.
PATRICi23598841. VBISheSp103602_2648.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000503 Genomic DNA. Translation: ABM25355.1 .
RefSeqi YP_963909.1. NC_008750.1.

3D structure databases

ProteinModelPortali A1RL10.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 351745.Sputw3181_2531.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABM25355 ; ABM25355 ; Sputw3181_2531 .
GeneIDi 4659819.
KEGGi shw:Sputw3181_2531.
PATRICi 23598841. VBISheSp103602_2648.

Phylogenomic databases

eggNOGi COG0295.
HOGENOMi HOG000218617.
KOi K01489.
OMAi NRSHAPY.
OrthoDBi EOG6XDH25.

Enzyme and pathway databases

BioCyci SSP351745:GCOY-2625-MONOMER.

Family and domain databases

HAMAPi MF_01558. Cyt_deam.
InterProi IPR016192. APOBEC/CMP_deaminase_Zn-bd.
IPR002125. CMP_dCMP_Zn-bd.
IPR013171. Cyd/dCyd_deaminase_Zn-bd.
IPR006263. Cyt_deam_dimer.
IPR016193. Cytidine_deaminase-like.
IPR020797. Cytidine_deaminase_bacteria.
[Graphical view ]
Pfami PF00383. dCMP_cyt_deam_1. 1 hit.
PF08211. dCMP_cyt_deam_2. 1 hit.
[Graphical view ]
PIRSFi PIRSF006334. Cdd_plus_pseudo. 1 hit.
SUPFAMi SSF53927. SSF53927. 2 hits.
PROSITEi PS00903. CYT_DCMP_DEAMINASES. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: W3-18-1.

Entry informationi

Entry nameiCDD_SHESW
AccessioniPrimary (citable) accession number: A1RL10
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: February 6, 2007
Last modified: May 14, 2014
This is version 46 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi