Reviewed, UniProtKB/Swiss-Prot A1RJD6 (ARAA_SHESW)

Names and origin

Protein names

Recommended name:
    L-arabinose isomerase
    EC=5.3.1.4

Gene names

Name:	araA
Ordered Locus Names:	Sputw3181_1946

Organism

Shewanella sp. (strain W3-18-1) [Complete proteome] [HAMAP]

Taxonomic identifier

351745 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Alteromonadales › Shewanellaceae › Shewanella

Protein attributes

Sequence length	500 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Catalyzes the conversion of L-arabinose to L-ribulose By similarity.
Catalytic activity	L-arabinose = L-ribulose. HAMAP MF_00519
Cofactor	Binds 1 manganese ion per subunit By similarity.
Pathway	Carbohydrate degradation; L-arabinose degradation via L-ribulose; D-xylulose 5-phosphate from L-arabinose (bacterial route): step 1/3. HAMAP MF_00519
Sequence similarities	Belongs to the arabinose isomerase family.

Ontologies

Keywords
Biological process	Arabinose catabolism Carbohydrate metabolism
Ligand	Manganese Metal-binding
Molecular function	Isomerase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	arabinose catabolic process Inferred from electronic annotation. Source: HAMAP
Molecular function	L-arabinose isomerase activity Inferred from electronic annotation. Source: HAMAP manganese ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 500	500	L-arabinose isomerase HAMAP MF_00519		PRO_0000312620
Sites
	Metal binding	306	1	Manganese By similarity
	Metal binding	333	1	Manganese By similarity
	Metal binding	349	1	Manganese By similarity
	Metal binding	448	1	Manganese By similarity

Sequences

	Sequence		Length	Mass (Da)
	A1RJD6-1 [UniParc]. Last modified December 4, 2007. Version 2. Checksum: 44AB0CA45785A47B	FASTA	500	55,640
	10 20 30 40 50 60 MKAFKQKQVW FVTGSQDLYG PKVLEQVAKN SEQIVNGFNQ SDAISMEVVY KPTVKSPREI 70 80 90 100 110 120 YAVCQAANSD ENCVGIILWM HTFSPAKMWI AGLNELSKPF MHLHTQFNAE LPWADINMNY 130 140 150 160 170 180 MNTHQSAHGC REFGYIGTRM RKERKVVVGH WQTNDVQAQV DDWCRAAAGW NESQNLRIAR 190 200 210 220 230 240 FGDNMRQVAV TEGDKVAAQI QFGYEVHAYS LGELNDAINA ISENDITAQI DRYASEYIIS 250 260 270 280 290 300 NELFNDEYQL DRLRKEAKIE LGLAQFLKDG EFGAFTNCFE NLTGMTGLPG LATQRLMANG 310 320 330 340 350 360 IGYGGEGDWK TAAMVRIMKV MGQGRVGGTS FMEDYTYNFG ATDQVLGAHM LEVCPSIAAS 370 380 390 400 410 420 KPRLEVHRHT IGVRCDVPRL LFTAKAGPAI NVSTIDLGNR FRIILNELDT VTPPQDLPNL 430 440 450 460 470 480 PVASALWEPR PNLSIAAAAW IHAGGAHHSA YSQAISTENI VDFAEMAGAE LVIIDADTQI 490 500 RQFKNELRQN SVYYGLARGL

References

[1]

"Complete sequence of Shewanella sp. W3-18-1." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M. , Hauser L., Kyrpides N., Lykidis A., Tiedje J., Richardson P. Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000503 Genomic DNA. Translation: ABM24781.1. Different initiation.
RefSeq	YP_963335.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	A1RJD6.
Genome annotation databases
GeneID	4660206.
GenomeReviews	Gene locus Sputw3181_1946 in contig CP000503_GR.
KEGG	shw:Sputw3181_1946.
Organism-specific databases
CMR	Search...
Family and domain databases
HAMAP	MF_00519. [Tree]
InterPro	IPR003762. Lara_isomerase. [Graphical view]
Pfam	PF02610. Arabinose_Isome. 1 hit. [Graphical view]
PIRSF	PIRSF001478. L-ara_isomerase. 1 hit.
ProDom	PD018364. Lara_isomerase. 2 hits. [Graphical view] [Entries sharing at least one domain]
ProtoNet	Search...

Entry information

Entry name

ARAA_SHESW

Accession

Primary (citable) accession number: A1RJD6

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 4, 2007
Last sequence update:	December 4, 2007
Last modified:	September 22, 2009
This is version 15 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)