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Reviewed, UniProtKB/Swiss-Prot A1RIU9 (ASTB_SHESW)

Last modified June 16, 2009. Version 14. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

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Names and origin

Protein namesRecommended name:
    N-succinylarginine dihydrolase
    EC=3.5.3.23
Gene names
Name: astB
Ordered Locus Names: Sputw3181_1757
OrganismShewanella sp. (strain W3-18-1) [Complete proteome] [HAMAP]
Taxonomic identifier351745 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Alteromonadales › Shewanellaceae › Shewanella

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Protein attributes

Sequence length444 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceInferred from homology.

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General annotation (Comments)

Function

Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO2 By similarity.

Catalytic activity

N(2)-succinyl-L-arginine + 2 H2O = N(2)-succinyl-L-ornithine + 2 NH3 + CO2. HAMAP MF_01172

Pathway

Amino-acid degradation; L-arginine degradation via AST pathway; L-glutamate and succinate from L-arginine: step 2/5. HAMAP MF_01172

Subunit structure

Homodimer By similarity.

Sequence similarities

Belongs to the succinylarginine dihydrolase family.

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Ontologies

Keywords
   Biological processArginine metabolism
   Molecular functionHydrolase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processarginine catabolic process to glutamate

Inferred from electronic annotation. Source: HAMAP

   Molecular functionN-succinylarginine dihydrolase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

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Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 444444N-succinylarginine dihydrolase HAMAP MF_01172
PRO_1000065741

Regions

Region19 – 2810Substrate binding By similarity
Region137 – 1382Substrate binding By similarity

Sites

Active site1741 By similarity
Active site2501 By similarity
Active site3681Nucleophile By similarity
Binding site1101Substrate By similarity
Binding site2141Substrate By similarity
Binding site2521Substrate By similarity
Binding site3621Substrate By similarity

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Sequences

Sequence LengthMass (Da)Tools
A1RIU9-1 [UniParc].

Last modified February 6, 2007. Version 1.
Checksum: D37488439A4A63AC

FASTA44449,198
        10         20         30         40         50         60 
MKHFEANFDG LVGPTHNYAG LSFGNVASLS NAALVSNPKA AAKQGLQKAK ALADMGIVQG 

        70         80         90        100        110        120 
MLAPQERPDL YTLRRIGFSG SDANVLKQAA KEAPILLNAC CSASSMWTAN AATVSPSADT 

       130        140        150        160        170        180 
RDGKLHFTPA NLVDKLHRSI EPLTTGRILT ATFSDPHYFH HHSHLPEHNS FGDEGAANHT 

       190        200        210        220        230        240 
RLCKEYGHAG VELFVYGQEA TNPNAPKPQK YPARQTLEAS MAVARLHQLE DDNCVFIQQN 

       250        260        270        280        290        300 
PDVIDQGVFH NDVIAVGNQN VLFYHEQAFL NTQQKIDEIK RKLDTELYFI EVPTAKVTIQ 

       310        320        330        340        350        360 
DAVKSYLFNT QIITLASGEM AIIAPTDCQE NPAVFAYLNE LLTLNTPIKQ VLYFDVKQSM 

       370        380        390        400        410        420 
QNGGGPACLR LRVAMNEKEI TAVNQHTLLN DALFNRLNTW IEKHYRDRLT TQDLADPQLI 

       430        440 
IESRTALDEL SQIMKLGSVY QFQK

« Hide

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References

[1]"Complete sequence of Shewanella sp. W3-18-1."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M. expand/collapse author list , Hauser L., Kyrpides N., Lykidis A., Tiedje J., Richardson P.
Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

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Cross-references

Sequence databases

CP000503 Genomic DNA. Translation: ABM24594.1.
RefSeqYP_963148.1.

3D structure databases

ModBaseSearch...

Genome annotation databases

GeneID4657989.
GenomeReviewsGene locus Sputw3181_1757 in contig CP000503_GR.
KEGGshw:Sputw3181_1757.
NMPDRfig|351745.7.peg.1646.

Organism-specific databases

CMRSearch...

Phylogenomic databases

OMAA1RIU9. HFAHHPA.

Family and domain databases

HAMAPMF_01172.
[Tree]
InterProIPR007079. SuccinylArg_d-Hdrlase_AstB.
[Graphical view]
Gene3DG3DSA:3.75.10.20. SuccinylArg_di_hydro. 1 hit.
PfamPF04996. AstB. 1 hit.
[Graphical view]
TIGRFAMsTIGR03241. arg_catab_astB. 1 hit.
ProtoNetSearch...

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Entry information

Entry nameASTB_SHESW
AccessionPrimary (citable) accession number: A1RIU9
Entry history
Integrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: February 6, 2007
Last modified: June 16, 2009
This is version 14 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

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Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents