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Protein

Glycosyl hydrolase family 109 protein

Gene

Sputw3181_1518

Organism
Shewanella sp. (strain W3-18-1)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Glycosidase.By similarity

Cofactori

NAD(+)By similarityNote: Binds 1 NAD(+) per subunit. The NAD(+) cannot dissociate.By similarity

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei86 – 861NADBy similarity
Binding sitei184 – 1841NADBy similarity
Binding sitei213 – 2131SubstrateBy similarity
Binding sitei232 – 2321SubstrateBy similarity
Binding sitei244 – 2441NADBy similarity
Binding sitei326 – 3261SubstrateBy similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi64 – 652NADBy similarity
Nucleotide bindingi135 – 1384NADBy similarity
Nucleotide bindingi155 – 1562NADBy similarity

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Glycosidase, Hydrolase

Keywords - Ligandi

NAD

Enzyme and pathway databases

BioCyciSSP351745:GCOY-1575-MONOMER.

Protein family/group databases

CAZyiGH109. Glycoside Hydrolase Family 109.

Names & Taxonomyi

Protein namesi
Recommended name:
Glycosyl hydrolase family 109 protein (EC:3.2.1.-)
Gene namesi
Ordered Locus Names:Sputw3181_1518
OrganismiShewanella sp. (strain W3-18-1)
Taxonomic identifieri351745 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesShewanellaceaeShewanella

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 3131Tat-type signalPROSITE-ProRule annotationAdd
BLAST
Chaini32 – 459428Glycosyl hydrolase family 109 proteinPRO_5000203918Add
BLAST

Post-translational modificationi

Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.

Structurei

3D structure databases

ProteinModelPortaliA1RI61.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni244 – 2474Substrate bindingBy similarity

Sequence similaritiesi

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiNOG125103.
HOGENOMiHOG000252553.
OMAiMESGKHA.
OrthoDBiEOG61P6MK.

Family and domain databases

Gene3Di3.40.50.720. 2 hits.
InterProiIPR016040. NAD(P)-bd_dom.
IPR000683. Oxidoreductase_N.
IPR006311. TAT_signal.
IPR019546. TAT_signal_bac_arc.
[Graphical view]
PfamiPF01408. GFO_IDH_MocA. 1 hit.
PF10518. TAT_signal. 1 hit.
[Graphical view]
PROSITEiPS51318. TAT. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

A1RI61-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MHNIHRRHFL KAAGAVTAGL ITANITASTH ANSVAPKPQT GKSVIGLIAP
60 70 80 90 100
KMDVVRVGFI GVGERGFSHV EQFCHLEGVE LKAICDTHQA VIDRAVAHIA
110 120 130 140 150
KQNRPQPTVY TGDDLSYRDL LSRDDIDIVI ISTPWEWHAP MAIETMESGK
160 170 180 190 200
HAFVEVPLAL TVEECWQIVD TAERTQKNCM MMENVNYGRE ELMVLNMVRQ
210 220 230 240 250
GVFGELLHGE AAYIHELRWQ MKEIDHKTGS WRTYWHTKRN GNLYPTHGLG
260 270 280 290 300
PVSQYMNINR GDRFDYLTSM SSPALGRALY AKREFPADHE RNQLKYINGD
310 320 330 340 350
INTSLIKTVK GRTIMVQHDT TTPRPYSRHN LIQGTNGVFA GFPNRIAVEH
360 370 380 390 400
GGFGKSYHEW DMDMQKWYDK YDHPLWQRIG KEAEINGGHG GMDFVMLWRM
410 420 430 440 450
IYCLRNGEAL DQDVYDAASW SVVNILSEQS VNNRSNSVTF PDFTRGAWEH

AKPLGIVGA
Length:459
Mass (Da):51,985
Last modified:February 6, 2007 - v1
Checksum:i29C03823D4C4C1FB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000503 Genomic DNA. Translation: ABM24356.1.
RefSeqiWP_011788857.1. NC_008750.1.

Genome annotation databases

EnsemblBacteriaiABM24356; ABM24356; Sputw3181_1518.
KEGGishw:Sputw3181_1518.
PATRICi23596625. VBISheSp103602_1579.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000503 Genomic DNA. Translation: ABM24356.1.
RefSeqiWP_011788857.1. NC_008750.1.

3D structure databases

ProteinModelPortaliA1RI61.
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

CAZyiGH109. Glycoside Hydrolase Family 109.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABM24356; ABM24356; Sputw3181_1518.
KEGGishw:Sputw3181_1518.
PATRICi23596625. VBISheSp103602_1579.

Phylogenomic databases

eggNOGiNOG125103.
HOGENOMiHOG000252553.
OMAiMESGKHA.
OrthoDBiEOG61P6MK.

Enzyme and pathway databases

BioCyciSSP351745:GCOY-1575-MONOMER.

Family and domain databases

Gene3Di3.40.50.720. 2 hits.
InterProiIPR016040. NAD(P)-bd_dom.
IPR000683. Oxidoreductase_N.
IPR006311. TAT_signal.
IPR019546. TAT_signal_bac_arc.
[Graphical view]
PfamiPF01408. GFO_IDH_MocA. 1 hit.
PF10518. TAT_signal. 1 hit.
[Graphical view]
PROSITEiPS51318. TAT. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: W3-18-1.

Entry informationi

Entry nameiGH109_SHESW
AccessioniPrimary (citable) accession number: A1RI61
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 2, 2008
Last sequence update: February 6, 2007
Last modified: July 22, 2015
This is version 55 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Documents

  1. Glycosyl hydrolases
    Classification of glycosyl hydrolase families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.