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A1RHL2

- GLSA_SHESW

UniProt

A1RHL2 - GLSA_SHESW

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Protein

Glutaminase

Gene
glsA, Sputw3181_1314
Organism
Shewanella sp. (strain W3-18-1)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

L-glutamine + H2O = L-glutamate + NH3.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei63 – 631Substrate By similarity
Binding sitei114 – 1141Substrate By similarity
Binding sitei158 – 1581Substrate By similarity
Binding sitei165 – 1651Substrate By similarity
Binding sitei189 – 1891Substrate By similarity
Binding sitei240 – 2401Substrate By similarity
Binding sitei258 – 2581Substrate; via amide nitrogen By similarity

GO - Molecular functioni

  1. glutaminase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. glutamine metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Enzyme and pathway databases

BioCyciSSP351745:GCOY-1357-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Glutaminase (EC:3.5.1.2)
Gene namesi
Name:glsA
Ordered Locus Names:Sputw3181_1314
OrganismiShewanella sp. (strain W3-18-1)
Taxonomic identifieri351745 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesShewanellaceaeShewanella
ProteomesiUP000002597: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 304304GlutaminaseUniRule annotationPRO_1000048363Add
BLAST

Interactioni

Subunit structurei

Homotetramer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi351745.Sputw3181_1314.

Structurei

3D structure databases

ProteinModelPortaliA1RHL2.

Family & Domainsi

Sequence similaritiesi

Belongs to the glutaminase family.

Phylogenomic databases

eggNOGiCOG2066.
HOGENOMiHOG000216890.
KOiK01425.
OMAiMSIAVWS.
OrthoDBiEOG6N94BK.

Family and domain databases

Gene3Di3.40.710.10. 1 hit.
HAMAPiMF_00313. Glutaminase.
InterProiIPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view]
PANTHERiPTHR12544. PTHR12544. 1 hit.
PfamiPF04960. Glutaminase. 1 hit.
[Graphical view]
SUPFAMiSSF56601. SSF56601. 1 hit.
TIGRFAMsiTIGR03814. Gln_ase. 1 hit.

Sequencei

Sequence statusi: Complete.

A1RHL2-1 [UniParc]FASTAAdd to Basket

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MPELALLEEV VEKVRPLLGQ GKVANYIPAL ASVDAGKLGI AVTTVDGETL    50
GAGDYLEPFS IQSISKVFSL TLALTLYEEA EIWSRVGKEP SGHSFNSLVQ 100
VELERGKPRN PFINAGALVI ADLLQSRLGA PKHRMLELVR QLSQNDKVCF 150
DKQVADSEYQ HSARNAAIAY LMKSFGNFQG DVDTVLRTYF HYCALKMNCA 200
DLSRAMLYLA NRGKTVDGTE LISQVQTRQL NALLATSGLY DGAGEFAYRV 250
GMPGKSGVGG GIIAVIPGEL SICVWSPELD ENGNSLAGTA MLEHLSQRLG 300
RSIF 304
Length:304
Mass (Da):32,911
Last modified:February 6, 2007 - v1
Checksum:iD9C219EE77DEC89B
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000503 Genomic DNA. Translation: ABM24157.1.
RefSeqiYP_962711.1. NC_008750.1.

Genome annotation databases

EnsemblBacteriaiABM24157; ABM24157; Sputw3181_1314.
GeneIDi4659211.
KEGGishw:Sputw3181_1314.
PATRICi23596177. VBISheSp103602_1370.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000503 Genomic DNA. Translation: ABM24157.1 .
RefSeqi YP_962711.1. NC_008750.1.

3D structure databases

ProteinModelPortali A1RHL2.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 351745.Sputw3181_1314.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABM24157 ; ABM24157 ; Sputw3181_1314 .
GeneIDi 4659211.
KEGGi shw:Sputw3181_1314.
PATRICi 23596177. VBISheSp103602_1370.

Phylogenomic databases

eggNOGi COG2066.
HOGENOMi HOG000216890.
KOi K01425.
OMAi MSIAVWS.
OrthoDBi EOG6N94BK.

Enzyme and pathway databases

BioCyci SSP351745:GCOY-1357-MONOMER.

Family and domain databases

Gene3Di 3.40.710.10. 1 hit.
HAMAPi MF_00313. Glutaminase.
InterProi IPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view ]
PANTHERi PTHR12544. PTHR12544. 1 hit.
Pfami PF04960. Glutaminase. 1 hit.
[Graphical view ]
SUPFAMi SSF56601. SSF56601. 1 hit.
TIGRFAMsi TIGR03814. Gln_ase. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: W3-18-1.

Entry informationi

Entry nameiGLSA_SHESW
AccessioniPrimary (citable) accession number: A1RHL2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: February 6, 2007
Last modified: May 14, 2014
This is version 44 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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