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A1RHL2 (GLSA_SHESW) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 43. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glutaminase

EC=3.5.1.2
Gene names
Name:glsA
Ordered Locus Names:Sputw3181_1314
OrganismShewanella sp. (strain W3-18-1) [Complete proteome] [HAMAP]
Taxonomic identifier351745 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesShewanellaceaeShewanella

Protein attributes

Sequence length304 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

L-glutamine + H2O = L-glutamate + NH3. HAMAP-Rule MF_00313

Subunit structure

Homotetramer By similarity. HAMAP-Rule MF_00313

Sequence similarities

Belongs to the glutaminase family.

Ontologies

Keywords
   Molecular functionHydrolase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processglutamine metabolic process

Inferred from electronic annotation. Source: InterPro

   Molecular_functionglutaminase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 304304Glutaminase HAMAP-Rule MF_00313
PRO_1000048363

Sites

Binding site631Substrate By similarity
Binding site1141Substrate By similarity
Binding site1581Substrate By similarity
Binding site1651Substrate By similarity
Binding site1891Substrate By similarity
Binding site2401Substrate By similarity
Binding site2581Substrate; via amide nitrogen By similarity

Sequences

Sequence LengthMass (Da)Tools
A1RHL2 [UniParc].

Last modified February 6, 2007. Version 1.
Checksum: D9C219EE77DEC89B

FASTA30432,911
        10         20         30         40         50         60 
MPELALLEEV VEKVRPLLGQ GKVANYIPAL ASVDAGKLGI AVTTVDGETL GAGDYLEPFS 

        70         80         90        100        110        120 
IQSISKVFSL TLALTLYEEA EIWSRVGKEP SGHSFNSLVQ VELERGKPRN PFINAGALVI 

       130        140        150        160        170        180 
ADLLQSRLGA PKHRMLELVR QLSQNDKVCF DKQVADSEYQ HSARNAAIAY LMKSFGNFQG 

       190        200        210        220        230        240 
DVDTVLRTYF HYCALKMNCA DLSRAMLYLA NRGKTVDGTE LISQVQTRQL NALLATSGLY 

       250        260        270        280        290        300 
DGAGEFAYRV GMPGKSGVGG GIIAVIPGEL SICVWSPELD ENGNSLAGTA MLEHLSQRLG 


RSIF 

« Hide

References

[1]"Complete sequence of Shewanella sp. W3-18-1."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M. expand/collapse author list , Hauser L., Kyrpides N., Lykidis A., Tiedje J., Richardson P.
Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: W3-18-1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000503 Genomic DNA. Translation: ABM24157.1.
RefSeqYP_962711.1. NC_008750.1.

3D structure databases

ProteinModelPortalA1RHL2.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING351745.Sputw3181_1314.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABM24157; ABM24157; Sputw3181_1314.
GeneID4659211.
KEGGshw:Sputw3181_1314.
PATRIC23596177. VBISheSp103602_1370.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG2066.
HOGENOMHOG000216890.
KOK01425.
OMAVNSIMAT.
OrthoDBEOG6N94BK.
ProtClustDBPRK00971.

Enzyme and pathway databases

BioCycSSP351745:GCOY-1357-MONOMER.

Family and domain databases

Gene3D3.40.710.10. 1 hit.
HAMAPMF_00313. Glutaminase.
InterProIPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view]
PANTHERPTHR12544. PTHR12544. 1 hit.
PfamPF04960. Glutaminase. 1 hit.
[Graphical view]
SUPFAMSSF56601. SSF56601. 1 hit.
TIGRFAMsTIGR03814. Gln_ase. 1 hit.
ProtoNetSearch...

Entry information

Entry nameGLSA_SHESW
AccessionPrimary (citable) accession number: A1RHL2
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: February 6, 2007
Last modified: February 19, 2014
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families