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A1REA8 (RPOC_SHESW) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 46. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
DNA-directed RNA polymerase subunit beta'

Short name=RNAP subunit beta'
EC=2.7.7.6
Alternative name(s):
RNA polymerase subunit beta'
Transcriptase subunit beta'
Gene names
Name:rpoC
Ordered Locus Names:Sputw3181_0150
OrganismShewanella sp. (strain W3-18-1) [Complete proteome] [HAMAP]
Taxonomic identifier351745 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesShewanellaceaeShewanella

Protein attributes

Sequence length1405 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates By similarity. HAMAP-Rule MF_01322

Catalytic activity

Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). HAMAP-Rule MF_01322

Subunit structure

The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription By similarity.

Sequence similarities

Belongs to the RNA polymerase beta' chain family.

Ontologies

Keywords
   Biological processTranscription
   Cellular componentDNA-directed RNA polymerase
   Molecular functionNucleotidyltransferase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processtranscription, DNA-templated

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Molecular_functionDNA binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

DNA-directed RNA polymerase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 14051405DNA-directed RNA polymerase subunit beta' HAMAP-Rule MF_01322
PRO_0000308882

Sequences

Sequence LengthMass (Da)Tools
A1REA8 [UniParc].

Last modified February 6, 2007. Version 1.
Checksum: B5EA18D00A1330AB

FASTA1,405155,298
        10         20         30         40         50         60 
MKDLLKFLKQ QSKTEEFNGI KIGLASPDLI RSWSFGEVKK PETINYRTFK PEREGLFCAR 

        70         80         90        100        110        120 
IFGPVKDYEC LCGKYKRLKH RGVICEKCGV EVTQTKVRRE RMGHIELASP VAHIWFLKSL 

       130        140        150        160        170        180 
PSRIGLMLDM TLRDIERVLY FESFVVIEPG MTSLERGQML TEETYLDALE EYGDEFEAKM 

       190        200        210        220        230        240 
GAEAVLELLR AIDLAKEIEQ MREELPSINS ETRRKKVTKR LKLMEAFFTS GNKPEWMILK 

       250        260        270        280        290        300 
VLPVLPPDLR PLVPLDGGRF ATSDLNDLYR RVINRNNRLK RLLDLAAPDI IVRNEKRMLQ 

       310        320        330        340        350        360 
ESVDALLDNG RRGRAITGSN KRPLKSLADM IKGKQGRFRQ NLLGKRVDYS GRSVITVGPT 

       370        380        390        400        410        420 
LRLHQCGLPK KMALELFKPF IYGKLEGRGL ATTIKAAKKM VEREVAEVWD VLDEVIREHP 

       430        440        450        460        470        480 
VMLNRAPTLH RLGIQAFEPV LIEGKAIQLH PLVCAAYNAD FDGDQMAVHV PLTLEAQLEA 

       490        500        510        520        530        540 
RALMMSTNNI LSPANGEPVI TPSQDVVLGL YYTSRERING RGEGMAFMSV AEVEKAYATG 

       550        560        570        580        590        600 
AAELHARVKV RITETIIGDD GERTEQRRIV DTTVGRALLS LILPAGLSFD LVNQNMGKKQ 

       610        620        630        640        650        660 
ISKLLNTCYR QLGLKDTVIF ADQLMYTGFR FATISGASVG IDDMVIPDEK YTLVADAEAE 

       670        680        690        700        710        720 
VLEIQEQFQS GLVTAGERYN KVIDIWASAN EKVSKAMMEN LSTETVINRD GVEEKQASFN 

       730        740        750        760        770        780 
SIYMMADSGA RGSAAQIRQL AGMRGLMAKP DGSIIETPIT ANFREGLNVL QYFISTHGAR 

       790        800        810        820        830        840 
KGLADTALKT ANSGYLTRRL VDVAQDLVVI EDDCGTHEGL TMKPLIEGGD VVEPLRERVL 

       850        860        870        880        890        900 
GRVVAVDVFY PGTEDVLAPR NTLLDEAWCD KLEEHSIDEV IVRSVITCDT DFGVCAACYG 

       910        920        930        940        950        960 
RDLARGHIIN HGEAIGVVAA QSIGEPGTQL TMRTFHIGGA ASRASAENNV QVKNSGSLKL 

       970        980        990       1000       1010       1020 
HNAKHVTNSD GKLVIVSRSS ELAIIDELGR EKERYKVPYG TVLEKLEEAA VEAGDIIANW 

      1030       1040       1050       1060       1070       1080 
DPHTHPIISE VAGSIKFVDM IDGVTMTRQT DELTGLSSIV ILDVGQRGTA GKEMRPMIRL 

      1090       1100       1110       1120       1130       1140 
LGANGSDLMI PGTEVPAQYF LPGSAIVNLD DNAQIAVGDA LARIPQESSK TRDITGGLPR 

      1150       1160       1170       1180       1190       1200 
VADLFEARKP KEPAILAEIS GTISFGKETK GKRRLVITPA DGGDQYEEMI PKWRNLNVFE 

      1210       1220       1230       1240       1250       1260 
GEKVERGEVI ADGPEAAHDI LRLRGIHNVA NYIVNEVQDV YRLQGVKIND KHIEVIIRQM 

      1270       1280       1290       1300       1310       1320 
LRKCLITSAG DTEFLEGEQV EVSRVKIANR ELIAQGKVPA TFERELLGIT KASLATESFI 

      1330       1340       1350       1360       1370       1380 
SAASFQETTR VLTEAAVGGK SDQLRGLKEN VIVGRLIPAG TGYAYHKTRN DARAKKDEPV 

      1390       1400 
VVNKVTASEA EQNLADLLNM AGSQD 

« Hide

References

[1]"Complete sequence of Shewanella sp. W3-18-1."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M. expand/collapse author list , Hauser L., Kyrpides N., Lykidis A., Tiedje J., Richardson P.
Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: W3-18-1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000503 Genomic DNA. Translation: ABM23003.1.
RefSeqYP_961557.1. NC_008750.1.

3D structure databases

ProteinModelPortalA1REA8.
SMRA1REA8. Positions 944-1128.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING351745.Sputw3181_0150.

Proteomic databases

PRIDEA1REA8.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABM23003; ABM23003; Sputw3181_0150.
GeneID4660327.
KEGGshw:Sputw3181_0150.
PATRIC23593675. VBISheSp103602_0155.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0086.
HOGENOMHOG000218386.
KOK03046.
OMAIYFAAYM.
OrthoDBEOG6M9DS6.
ProtClustDBPRK00566.

Enzyme and pathway databases

BioCycSSP351745:GCOY-157-MONOMER.

Family and domain databases

HAMAPMF_01322. RNApol_bact_RpoC.
InterProIPR012754. DNA-dir_RpoC_beta_prime.
IPR000722. RNA_pol_asu.
IPR006592. RNA_pol_N.
IPR007080. RNA_pol_Rpb1_1.
IPR007066. RNA_pol_Rpb1_3.
IPR007083. RNA_pol_Rpb1_4.
IPR007081. RNA_pol_Rpb1_5.
[Graphical view]
PfamPF04997. RNA_pol_Rpb1_1. 1 hit.
PF00623. RNA_pol_Rpb1_2. 1 hit.
PF04983. RNA_pol_Rpb1_3. 1 hit.
PF05000. RNA_pol_Rpb1_4. 1 hit.
PF04998. RNA_pol_Rpb1_5. 1 hit.
[Graphical view]
SMARTSM00663. RPOLA_N. 1 hit.
[Graphical view]
TIGRFAMsTIGR02386. rpoC_TIGR. 1 hit.
ProtoNetSearch...

Entry information

Entry nameRPOC_SHESW
AccessionPrimary (citable) accession number: A1REA8
Entry history
Integrated into UniProtKB/Swiss-Prot: October 23, 2007
Last sequence update: February 6, 2007
Last modified: February 19, 2014
This is version 46 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families