A1RBR6 (A1RBR6_ARTAT) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Aminomethyltransferase 2 HAMAP MF_00259
EC=2.1.2.10 HAMAP MF_00259

Alternative name(s):
Glycine cleavage system T protein 2 HAMAP MF_00259

Gene names

Name:	gcvT EMBL ABM08116.1
Synonyms:	gcvT2 HAMAP MF_00259
Ordered Locus Names:	AAur_4006

Organism

Arthrobacter aurescens (strain TC1) [Complete proteome] [HAMAP] EMBL ABM08116.1

Taxonomic identifier

290340 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Micrococcineae › Micrococcaceae › Arthrobacter

Protein attributes

Sequence length	373 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	The glycine cleavage system catalyzes the degradation of glycine By similarity. HAMAP MF_00259
Catalytic activity	[Protein]-S(8)-aminomethyldihydrolipoyllysine + tetrahydrofolate = [protein]-dihydrolipoyllysine + 5,10-methylenetetrahydrofolate + NH3. HAMAP MF_00259
Subunit structure	The glycine cleavage system is composed of four proteins: P, T, L and H By similarity. HAMAP MF_00259
Sequence similarities	Belongs to the GcvT family. HAMAP MF_00259

Ontologies

Keywords
Molecular function	Aminotransferase HAMAP MF_00259 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycine decarboxylation via glycine cleavage system Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: InterPro
Molecular function	aminomethyltransferase activity Inferred from electronic annotation. Source: HAMAP transaminase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A1RBR6 [UniParc]. Last modified February 6, 2007. Version 1. Checksum: 2FF98F3275AE96F4	FASTA	373	39,530
	10 20 30 40 50 60 MSENYTALYE QHKKAGASFT DFGGWQMPLK YESELAEHHA VRNAAGLFDL SHMGEVWVSG 70 80 90 100 110 120 PDAAAFLDYA LVGKLSAIAV GKAKYSLICN ADGGIIDDLI SYRRAEDKYL VVPNAGNAKV 130 140 150 160 170 180 VSAALLKRAA GFDVVVEDVS AETSLIAVQG PTAEAILLQL VHAEQHELVT ELKYYAAVEV 190 200 210 220 230 240 SINGEDLLLA RTGYTGEDGF EIYVPNVDAA GLWEALLEAG EGHGLIPAGL AARDSLRLEA 250 260 270 280 290 300 GMPLYGNELS QHVNAYAAGL GPVVSLAKES DFVGREALTA IKAAGVGSTL GQKLVGLKGT 310 320 330 340 350 360 GRRAARAHYS VLKDGSLIGE VSSGQPSPTL GYPVAMAYVD VEHSEPGTIV EVDLRGKAEP 370 FEVVALPFYK RQK

References

[1]

"Secrets of soil survival revealed by the genome sequence of Arthrobacter aurescens TC1." Mongodin E.F., Shapir N., Daugherty S.C., DeBoy R.T., Emerson J.B., Shvartzbeyn A., Radune D., Vamathevan J., Riggs F., Grinberg V., Khouri H.M., Wackett L.P., Nelson K.E., Sadowsky M.J. PLoS Genet. 2:2094-2106(2006) [PubMed: 17194220] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000474 Genomic DNA. Translation: ABM08116.1.
RefSeq	YP_949678.1. NC_008711.1.
3D structure databases
ProteinModelPortal	A1RBR6.
ModBase	Search...
Protein-protein interaction databases
STRING	A1RBR6.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4638718.
GenomeReviews	Gene locus AAur_4006 in contig CP000474_GR.
KEGG	aau:AAur_4006.
PATRIC	20983580. VBIArtAur67810_4087.
TIGR	AAur_4006.
Phylogenomic databases
eggNOG	COG0404.
HOGENOM	HBG299834.
OMA	KALYGGM.
ProtClustDB	PRK00389.
Family and domain databases
HAMAP	MF_00259. GcvT. [Tree]
InterPro	IPR013977. GCV_T_C. IPR006222. GCV_T_N. IPR006223. GcvT. IPR022903. NH2_Me_Trfase. [Graphical view]
KO	K00605.
PANTHER	PTHR13847:SF5. PTHR13847:SF5. 1 hit.
Pfam	PF01571. GCV_T. 1 hit. PF08669. GCV_T_C. 1 hit. [Graphical view]
PIRSF	PIRSF006487. GcvT. 1 hit.
TIGRFAMs	TIGR00528. GcvT. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A1RBR6_ARTAT

Accession

Primary (citable) accession number: A1RBR6

Entry history

Integrated into UniProtKB/TrEMBL:	February 6, 2007
Last sequence update:	February 6, 2007
Last modified:	December 14, 2011
This is version 38 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)