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A1RBR4 (A1RBR4_ARTAT) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 46. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Serine hydroxymethyltransferase 3 HAMAP MF_00051
Short name=SHMT 3 HAMAP MF_00051
Short name=Serine methylase 3 HAMAP MF_00051
EC=2.1.2.1 HAMAP MF_00051
Gene names
Name:glyA EMBL ABM06576.1
Synonyms:glyA3 HAMAP MF_00051
Ordered Locus Names:AAur_4004
OrganismArthrobacter aurescens (strain TC1) [Complete proteome] [HAMAP] EMBL ABM06576.1
Taxonomic identifier290340 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Micrococcineae › Micrococcaceae › Arthrobacter

Protein attributes

Sequence length439 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Interconversion of serine and glycine By similarity. HAMAP MF_00051

Catalytic activity

5,10-methylenetetrahydrofolate + glycine + H2O = tetrahydrofolate + L-serine. HAMAP MF_00051

Cofactor

Pyridoxal phosphate By similarity. HAMAP MF_00051

Pathway

One-carbon metabolism; tetrahydrofolate interconversion. HAMAP MF_00051

Subunit structure

Homotetramer By similarity. HAMAP MF_00051

Subcellular location

Cytoplasm By similarity HAMAP MF_00051.

Sequence similarities

Belongs to the SHMT family. HAMAP MF_00051

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Amino acid modifications

Modified residue2431N6-(pyridoxal phosphate)lysine By similarity HAMAP MF_00051

Sequences

Sequence LengthMass (Da)Tools
A1RBR4 [UniParc].

Last modified February 6, 2007. Version 1.
Checksum: AAB1A18F4B1775F9

FASTA43946,880
        10         20         30         40         50         60 
MNPVSVTEYQ QVVSASLDAQ LSELDPEIAA KIDDELGRQR DGLEMIASEN HTAVAVMQAQ 

        70         80         90        100        110        120 
GSVLTNKYAE GYPGKRYYGG CEHVDVIEQL AIDRIKALFG AEFANVQPHS GAQANASVMH 

       130        140        150        160        170        180 
ALIKPGDTIM GLNLAHGGHL THGMRINFSG KLYNVVPYGV REDTHTVDMA EVERLAQEHK 

       190        200        210        220        230        240 
PALIVAGWSA YARQLDFAEF RRIADSVGAY LMVDMAHFAG LVAAGLHPSP VPHAHVTTST 

       250        260        270        280        290        300 
THKTLAGPRG GIILSNDADI AKKINSAVFP GQQGGPLEHV IAGKAVAFKI AASEEFRERQ 

       310        320        330        340        350        360 
ERVLAGARIL AERLVQPDVA AKGINVVSGG TDVHLVLVDL RNCELDGQQA EDRLAAIDIT 

       370        380        390        400        410        420 
VNRNAVPFDP RPPMVTSGLR IGTPALATRG FGEAAFREVA DIIAEVLIAD ADADLTGLRH 

       430 
RVEALAKAHP LYPGVANLG

« Hide

References

[1]"Secrets of soil survival revealed by the genome sequence of Arthrobacter aurescens TC1."
Mongodin E.F., Shapir N., Daugherty S.C., DeBoy R.T., Emerson J.B., Shvartzbeyn A., Radune D., Vamathevan J., Riggs F., Grinberg V., Khouri H.M., Wackett L.P., Nelson K.E., Sadowsky M.J.
PLoS Genet. 2:2094-2106(2006) [PubMed: 17194220] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000474 Genomic DNA. Translation: ABM06576.1.
RefSeqYP_949676.1. NC_008711.1.

3D structure databases

ProteinModelPortalA1RBR4.
ModBaseSearch...

Protein-protein interaction databases

STRINGA1RBR4.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4641083.
GenomeReviewsGene locus AAur_4004 in contig CP000474_GR.
KEGGaau:AAur_4004.
PATRIC20983576. VBIArtAur67810_4085.
TIGRAAur_4004.

Phylogenomic databases

eggNOGCOG0112.
HOGENOMHBG301263.
OMAGTSNHLM.
ProtClustDBCLSK959533.

Family and domain databases

HAMAPMF_00051. SHMT.
[Tree]
InterProIPR015424. PyrdxlP-dep_Trfase_major_dom.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
IPR001085. Ser_HO-MeTrfase.
IPR019798. Ser_HO-MeTrfase_PLP_BS.
[Graphical view]
Gene3DG3DSA:3.40.640.10. PyrdxlP-dep_Trfase_major_sub1. 1 hit.
G3DSA:3.90.1150.10. PyrdxlP-dep_Trfase_major_sub2. 1 hit.
KOK00600.
PANTHERPTHR11680. Gly_HO-Metrfase. 1 hit.
PfamPF00464. SHMT. 1 hit.
[Graphical view]
PIRSFPIRSF000412. SHMT. 1 hit.
SUPFAMSSF53383. PyrdxlP-dep_Trfase_major. 1 hit.
PROSITEPS00096. SHMT. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA1RBR4_ARTAT
AccessionPrimary (citable) accession number: A1RBR4
Entry history
Integrated into UniProtKB/TrEMBL: February 6, 2007
Last sequence update: February 6, 2007
Last modified: January 25, 2012
This is version 46 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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