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A1RBC4 (MTLD_ARTAT) Reviewed, UniProtKB/Swiss-Prot

Last modified December 14, 2011. Version 39. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Mannitol-1-phosphate 5-dehydrogenase
EC=1.1.1.17
Gene names
Name:mtlD
Ordered Locus Names:AAur_3858
OrganismArthrobacter aurescens (strain TC1) [Complete proteome] [HAMAP]
Taxonomic identifier290340 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Micrococcineae › Micrococcaceae › Arthrobacter

Protein attributes

Sequence length382 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-mannitol 1-phosphate + NAD+ = D-fructose 6-phosphate + NADH. HAMAP MF_00196

Sequence similarities

Belongs to the mannitol dehydrogenase family.

Ontologies

Keywords
   LigandNAD
   Molecular functionOxidoreductase
   Technical termComplete proteome
Gene Ontology (GO)
   Molecular functioncoenzyme binding

Inferred from electronic annotation. Source: InterPro

mannitol-1-phosphate 5-dehydrogenase activity

Inferred from electronic annotation. Source: EC

nucleotide binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 382382Mannitol-1-phosphate 5-dehydrogenase HAMAP MF_00196
PRO_1000011792

Regions

Nucleotide binding3 – 1412NAD By similarity

Sequences

Sequence LengthMass (Da)Tools
A1RBC4 [UniParc].

Last modified February 6, 2007. Version 1.
Checksum: 4F916BE9A989995B

FASTA38240,753
        10         20         30         40         50         60 
MKAVHFGAGN IGRGFVGLLL HEAGYEVVFA DVADALISQL ASASSYDVHE VGENPAVKTV 

        70         80         90        100        110        120 
SGFRAFNSAS QEAAVVEEIS TADVLTTAVG PHILKFVAPV IARGLAVRPA DLPPLQVMAC 

       130        140        150        160        170        180 
ENAINATDLL HTEIRAAWDD SAGDLDAVAV FANTAVDRIV PNQAPGQGLD VTVETFYEWV 

       190        200        210        220        230        240 
IDRTPFGGNA PKIPGATFVD ELGPYIERKL FTVNTGHASA AYFGYAAGLE KISDAMADPA 

       250        260        270        280        290        300 
VAAKVRAVLE ETKELLVAKH GFEEAEQEAY VQKILSRFTN PHLPDTVNRV GRAPLRKLSR 

       310        320        330        340        350        360 
HERFVGPAAE LAERGVTPAA LLEAMSAALR FDDGNDDEAV ELTNLLSELD AAAAVERITE 

       370        380 
LTPTHPLFPA LQKLVEDRQA EA

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References

[1]"Secrets of soil survival revealed by the genome sequence of Arthrobacter aurescens TC1."
Mongodin E.F., Shapir N., Daugherty S.C., DeBoy R.T., Emerson J.B., Shvartzbeyn A., Radune D., Vamathevan J., Riggs F., Grinberg V., Khouri H.M., Wackett L.P., Nelson K.E., Sadowsky M.J.
PLoS Genet. 2:2094-2106(2006) [PubMed: 17194220] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: TC1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000474 Genomic DNA. Translation: ABM09759.1.
RefSeqYP_949536.1. NC_008711.1.

3D structure databases

ProteinModelPortalA1RBC4.
ModBaseSearch...

Protein-protein interaction databases

STRINGA1RBC4.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4639719.
GenomeReviewsGene locus AAur_3858 in contig CP000474_GR.
KEGGaau:AAur_3858.
PATRIC20983276. VBIArtAur67810_3935.
TIGRAAur_3858.

Phylogenomic databases

eggNOGCOG0246.
HOGENOMHBG568825.
OMAFANTAVD.
ProtClustDBPRK02318.

Enzyme and pathway databases

BioCycAAUR290340:AAUR_3858-MONOMER.

Family and domain databases

HAMAPMF_00196. Mannitol_dehydrog.
[Tree]
InterProIPR008927. 6-PGluconate_DH_C-like.
IPR013328. DH_multihelical.
IPR023028. Mannitol_1_phos_5_DH.
IPR000669. Mannitol_DH.
IPR013118. Mannitol_DH_C.
IPR013131. Mannitol_DH_N.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
Gene3DG3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
G3DSA:1.10.1040.10. Opine_DH. 1 hit.
KOK00009.
PfamPF01232. Mannitol_dh. 1 hit.
PF08125. Mannitol_dh_C. 1 hit.
[Graphical view]
PRINTSPR00084. MTLDHDRGNASE.
SUPFAMSSF48179. 6DGDH_C_like. 1 hit.
PROSITEPS00974. MANNITOL_DHGENASE. False negative.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameMTLD_ARTAT
AccessionPrimary (citable) accession number: A1RBC4
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: February 6, 2007
Last modified: December 14, 2011
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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