Reviewed, UniProtKB/Swiss-Prot A1RAY5 (ARAA_ARTAT)

Names and origin

Protein names

Recommended name:
    L-arabinose isomerase
    EC=5.3.1.4

Gene names

Name:	araA
Ordered Locus Names:	AAur_3711

Organism

Arthrobacter aurescens (strain TC1) [Complete proteome] [HAMAP]

Taxonomic identifier

290340 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Micrococcineae › Micrococcaceae › Arthrobacter

Protein attributes

Sequence length	511 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Catalyzes the conversion of L-arabinose to L-ribulose By similarity.
Catalytic activity	L-arabinose = L-ribulose. HAMAP MF_00519
Cofactor	Binds 1 manganese ion per subunit By similarity.
Pathway	Carbohydrate degradation; L-arabinose degradation via L-ribulose; D-xylulose 5-phosphate from L-arabinose (bacterial route): step 1/3. HAMAP MF_00519
Sequence similarities	Belongs to the arabinose isomerase family.

Ontologies

Keywords
Biological process	Arabinose catabolism Carbohydrate metabolism
Ligand	Manganese Metal-binding
Molecular function	Isomerase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	arabinose catabolic process Inferred from electronic annotation. Source: HAMAP
Molecular function	L-arabinose isomerase activity Inferred from electronic annotation. Source: HAMAP manganese ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 511	511	L-arabinose isomerase HAMAP MF_00519		PRO_0000312599
Sites
	Metal binding	316	1	Manganese By similarity
	Metal binding	343	1	Manganese By similarity
	Metal binding	360	1	Manganese By similarity
	Metal binding	459	1	Manganese By similarity

Sequences

	Sequence		Length	Mass (Da)
	A1RAY5-1 [UniParc]. Last modified February 6, 2007. Version 1. Checksum: 979585CE483C89E4	FASTA	511	55,799
	10 20 30 40 50 60 MPSATSNPAN NTSLEQYEVW FLTGSQHLYG EDVLKQVAAQ SQEIANALNA NSNVPVKLVW 70 80 90 100 110 120 KPVLTDSDAI RRTALEANAD DSVIGVTAWM HTFSPAKMWI QGLDALRKPL LHLHTQANRD 130 140 150 160 170 180 LPWADIDFDF MNLNQAAHGD REFGYIQSRL GVPRKTVVGH VSNPEVARQV GAWQRASAGW 190 200 210 220 230 240 AAVRTLKLTR FGDNMRNVAV TEGDKTEAEL RFGVSVNTWS VNELADAVHG AAESDVDSLV 250 260 270 280 290 300 AEYERLYEVV PELKKGGARH ESLRYSAKIE LGLRSFLEAN GSAAFTTSFE DLGALRQLPG 310 320 330 340 350 360 MAVQRLMADG YGFGAEGDWK TAILVRAAKV MGGDLPGGAS LMEDYTYHLE PGSEKILGAH 370 380 390 400 410 420 MLEVCPSLTA KKPRVEIHPL GIGGKEDPVR MVFDTDAGPG VVVALSDMRD RFRLVANVVD 430 440 450 460 470 480 VVDLDQPLPN LPVARALWEP KPNFATSAAA WLTAGAAHHT VLSTQVGLDV FEDFAEIAKT 490 500 510 ELLTIDEDTT IKQFKKELNW NAAYYKLAGG L

References

[1]

"Secrets of soil survival revealed by the genome sequence of Arthrobacter aurescens TC1." Mongodin E.F., Shapir N., Daugherty S.C., DeBoy R.T., Emerson J.B., Shvartzbeyn A., Radune D., Vamathevan J., Riggs F., Grinberg V., Khouri H.M., Wackett L.P., Nelson K.E., Sadowsky M.J. PLoS Genet. 2:2094-2106(2006) [PubMed: 17194220] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000474 Genomic DNA. Translation: ABM06985.1.
RefSeq	YP_949397.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	A1RAY5.
Genome annotation databases
GeneID	4638955.
GenomeReviews	Gene locus AAur_3711 in contig CP000474_GR.
KEGG	aau:AAur_3711.
TIGR	AAur_3711.
Phylogenomic databases
OMA	EVCPTIA.
Family and domain databases
HAMAP	MF_00519. [Tree]
InterPro	IPR003762. Lara_isomerase. [Graphical view]
Pfam	PF02610. Arabinose_Isome. 1 hit. [Graphical view]
PIRSF	PIRSF001478. L-ara_isomerase. 1 hit.
ProDom	PD018364. Lara_isomerase. 1 hit. [Graphical view] [Entries sharing at least one domain]
ProtoNet	Search...

Entry information

Entry name

ARAA_ARTAT

Accession

Primary (citable) accession number: A1RAY5

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 4, 2007
Last sequence update:	February 6, 2007
Last modified:	November 3, 2009
This is version 19 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)