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A1R958

- A1R958_ARTAT

UniProt

A1R958 - A1R958_ARTAT

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Protein
Submitted name:

4-aminobutyrate transaminase

Gene

gabT

Organism
Arthrobacter aurescens (strain TC1)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei295 – 2951N6-(pyridoxalphosphate)lysine (covalent)Imported

GO - Molecular functioni

  1. 4-aminobutyrate transaminase activity Source: UniProtKB-EC
  2. pyridoxal phosphate binding Source: InterPro

GO - Biological processi

  1. gamma-aminobutyric acid metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

AminotransferaseImported, Transferase

Keywords - Ligandi

Pyridoxal phosphateUniRule annotation

Enzyme and pathway databases

BioCyciAAUR290340:GI59-3068-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
4-aminobutyrate transaminaseImported (EC:2.6.1.19Imported)
Gene namesi
Name:gabTImported
Ordered Locus Names:AAur_3069Imported
OrganismiArthrobacter aurescens (strain TC1)Imported
Taxonomic identifieri290340 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesMicrococcineaeMicrococcaceaeArthrobacter
ProteomesiUP000000637: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi290340.AAur_3069.

Structurei

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4ATPX-ray2.80A/B/C/D/E/F/G/H/I/J/K/L1-456[»]
4ATQX-ray2.75A/B/C/D/E/F/G/H/I/J/K/L1-456[»]
ProteinModelPortaliA1R958.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0160.
HOGENOMiHOG000020206.
KOiK07250.
OMAiNSFTHTA.
OrthoDBiEOG6QVRHN.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
3.90.1150.10. 1 hit.
InterProiIPR004632. 4NH2But_aminotransferase_bac.
IPR005814. Aminotrans_3.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view]
PANTHERiPTHR11986. PTHR11986. 1 hit.
PfamiPF00202. Aminotran_3. 1 hit.
[Graphical view]
PIRSFiPIRSF000521. Transaminase_4ab_Lys_Orn. 1 hit.
SUPFAMiSSF53383. SSF53383. 1 hit.
TIGRFAMsiTIGR00700. GABAtrnsam. 1 hit.
PROSITEiPS00600. AA_TRANSFER_CLASS_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A1R958 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MTTTANELSY RIEQKRNING AFPGPKSQAL AERRSAVVAA GVASGVPVYV
60 70 80 90 100
EDADGGIIRD VDGNSFIDLG SGIAVTSVGA SDPAVVAAVQ EAAAHFTHTC
110 120 130 140 150
FMVTPYEGYV AVAEQLNRLT PGDHAKRTVL FNSGAEAVEN AVKVARLATG
160 170 180 190 200
RDAVVAFDHA YHGRTNLTMA LTAKAMPYKT NFGPFAPEVY RMPMSYPFRE
210 220 230 240 250
ENPEITGAEA AKRAITMIEK QIGGDQVAAI IIEPIQGEGG FIVPAEGFLP
260 270 280 290 300
ALSEWAKEKG IVFIADEVQS GFCRTGEWFA VDHEGVVPDI ITMAKGIAGG
310 320 330 340 350
LPLSAITGRA DLLDAVHPGG LGGTYGGNPV ACAAALAAID TMEQHDLNGR
360 370 380 390 400
ARHIEELALG KLRELAAELS AGGGSVVGDI RGRGAMLAIE LVQPGSKEPN
410 420 430 440 450
AELTKAVAAA CLKEGVIILT CGTYGNVIRL LPPLVISDEL LIDGLEVLAA

AIKAHA
Length:456
Mass (Da):47,557
Last modified:February 6, 2007 - v1
Checksum:i7318C673C41B1ECB
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000474 Genomic DNA. Translation: ABM08874.1.
RefSeqiYP_948770.1. NC_008711.1.

Genome annotation databases

EnsemblBacteriaiABM08874; ABM08874; AAur_3069.
GeneIDi4640834.
KEGGiaau:AAur_3069.
PATRICi20981634. VBIArtAur67810_3121.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000474 Genomic DNA. Translation: ABM08874.1 .
RefSeqi YP_948770.1. NC_008711.1.

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
4ATP X-ray 2.80 A/B/C/D/E/F/G/H/I/J/K/L 1-456 [» ]
4ATQ X-ray 2.75 A/B/C/D/E/F/G/H/I/J/K/L 1-456 [» ]
ProteinModelPortali A1R958.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 290340.AAur_3069.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABM08874 ; ABM08874 ; AAur_3069 .
GeneIDi 4640834.
KEGGi aau:AAur_3069.
PATRICi 20981634. VBIArtAur67810_3121.

Phylogenomic databases

eggNOGi COG0160.
HOGENOMi HOG000020206.
KOi K07250.
OMAi NSFTHTA.
OrthoDBi EOG6QVRHN.

Enzyme and pathway databases

BioCyci AAUR290340:GI59-3068-MONOMER.

Family and domain databases

Gene3Di 3.40.640.10. 1 hit.
3.90.1150.10. 1 hit.
InterProi IPR004632. 4NH2But_aminotransferase_bac.
IPR005814. Aminotrans_3.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view ]
PANTHERi PTHR11986. PTHR11986. 1 hit.
Pfami PF00202. Aminotran_3. 1 hit.
[Graphical view ]
PIRSFi PIRSF000521. Transaminase_4ab_Lys_Orn. 1 hit.
SUPFAMi SSF53383. SSF53383. 1 hit.
TIGRFAMsi TIGR00700. GABAtrnsam. 1 hit.
PROSITEi PS00600. AA_TRANSFER_CLASS_3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: TC1Imported.
  2. "Structures of a ?-aminobutyrate (GABA) transaminase from the s-triazine-degrading organism Arthrobacter aurescens TC1 in complex with PLP and with its external aldimine PLP-GABA adduct."
    Bruce H., Nguyen Tuan A., Mangas Sanchez J., Leese C., Hopwood J., Hyde R., Hart S., Turkenburg J.P., Grogan G.
    Acta Crystallogr. F 68:1175-1180(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (2.75 ANGSTROMS) IN COMPLEX WITH N6-(PYRIDOXALPHOSPHATE)LYSINE.

Entry informationi

Entry nameiA1R958_ARTAT
AccessioniPrimary (citable) accession number: A1R958
Entry historyi
Integrated into UniProtKB/TrEMBL: February 6, 2007
Last sequence update: February 6, 2007
Last modified: October 1, 2014
This is version 54 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureImported, Complete proteome, Reference proteomeImported

External Data

Dasty 3