A1R958 (A1R958_ARTAT) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
4-aminobutyrate transaminase EMBL ABM08874.1
EC=2.6.1.19 EMBL ABM08874.1

Gene names

Name:	gabT EMBL ABM08874.1
Ordered Locus Names:	AAur_3069 EMBL ABM08874.1

Organism

Arthrobacter aurescens (strain TC1) [Complete proteome] [HAMAP] EMBL ABM08874.1

Taxonomic identifier

290340 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Actinobacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Micrococcineae › Micrococcaceae › Arthrobacter › Arthrobacter aurescens

Protein attributes

Sequence length	456 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Sequence similarities

Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. RuleBase RU003560

Ontologies

Keywords
Ligand	Pyridoxal phosphate RuleBase RU003560
Molecular function	Aminotransferase EMBL ABM08874.1 Transferase
Technical term	3D-structure PDB 4ATP PDB 4ATQ Complete proteome
Gene Ontology (GO)
Biological_process	gamma-aminobutyric acid metabolic process Inferred from electronic annotation. Source: InterPro
Molecular_function	4-aminobutyrate transaminase activity Inferred from electronic annotation. Source: EC pyridoxal phosphate binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A1R958 [UniParc]. Last modified February 6, 2007. Version 1. Checksum: 7318C673C41B1ECB	FASTA	456	47,557
	10 20 30 40 50 60 MTTTANELSY RIEQKRNING AFPGPKSQAL AERRSAVVAA GVASGVPVYV EDADGGIIRD 70 80 90 100 110 120 VDGNSFIDLG SGIAVTSVGA SDPAVVAAVQ EAAAHFTHTC FMVTPYEGYV AVAEQLNRLT 130 140 150 160 170 180 PGDHAKRTVL FNSGAEAVEN AVKVARLATG RDAVVAFDHA YHGRTNLTMA LTAKAMPYKT 190 200 210 220 230 240 NFGPFAPEVY RMPMSYPFRE ENPEITGAEA AKRAITMIEK QIGGDQVAAI IIEPIQGEGG 250 260 270 280 290 300 FIVPAEGFLP ALSEWAKEKG IVFIADEVQS GFCRTGEWFA VDHEGVVPDI ITMAKGIAGG 310 320 330 340 350 360 LPLSAITGRA DLLDAVHPGG LGGTYGGNPV ACAAALAAID TMEQHDLNGR ARHIEELALG 370 380 390 400 410 420 KLRELAAELS AGGGSVVGDI RGRGAMLAIE LVQPGSKEPN AELTKAVAAA CLKEGVIILT 430 440 450 CGTYGNVIRL LPPLVISDEL LIDGLEVLAA AIKAHA

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Secrets of soil survival revealed by the genome sequence of Arthrobacter aurescens TC1." Mongodin E.F., Shapir N., Daugherty S.C., DeBoy R.T., Emerson J.B., Shvartsbeyn A., Radune D., Vamathevan J., Riggs F., Grinberg V., Khouri H.M., Wackett L.P., Nelson K.E., Sadowsky M.J. PLoS Genet. 2:e214-e214(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: TC1 EMBL ABM08874.1.
[2]	"Structures of a ?-aminobutyrate (GABA) transaminase from the s-triazine-degrading organism Arthrobacter aurescens TC1 in complex with PLP and with its external aldimine PLP-GABA adduct." Bruce H., Nguyen Tuan A., Mangas Sanchez J., Leese C., Hopwood J., Hyde R., Hart S., Turkenburg J.P., Grogan G. Acta Crystallogr. F 68:1175-1180(2012) [PubMed] [Europe PMC] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (2.75 ANGSTROMS).

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

CP000474 Genomic DNA. Translation: ABM08874.1.

RefSeq

YP_948770.1. NC_008711.1.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
4ATP	X-ray	2.80	A/B/C/D/E/F/G/H/I/J/K/L	1-456	[»]
4ATQ	X-ray	2.75	A/B/C/D/E/F/G/H/I/J/K/L	1-456	[»]

ProteinModelPortal

A1R958.

ModBase

Search...

Protein-protein interaction databases

STRING

290340.AAur_3069.

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Genome annotation databases

EnsemblBacteria

ABM08874; ABM08874; AAur_3069.

GeneID

4640834.

KEGG

aau:AAur_3069.

PATRIC

20981634. VBIArtAur67810_3121.

Organism-specific databases

CMR

Search...

Phylogenomic databases

eggNOG

COG0160.

HOGENOM

HOG000020206.

KO

K07250.

OMA

CRTGAWF.

ProtClustDB

PRK06058.

Enzyme and pathway databases

BioCyc

AAUR290340:GI59-3649-MONOMER.

Family and domain databases

Gene3D

3.40.640.10. 1 hit.
3.90.1150.10. 1 hit.

InterPro

IPR004632. 4NH2But_aminotransferase_bac.
IPR005814. Aminotrans_3.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view]

PANTHER

PTHR11986. PTHR11986. 1 hit.

Pfam

PF00202. Aminotran_3. 1 hit.
[Graphical view]

SUPFAM

SSF53383. PyrdxlP-dep_Trfase_major. 1 hit.

TIGRFAMs

TIGR00700. GABAtrnsam. 1 hit.

PROSITE

PS00600. AA_TRANSFER_CLASS_3. 1 hit.
[Graphical view]

ProtoNet

Search...

Entry information

Entry name

A1R958_ARTAT

Accession

Primary (citable) accession number: A1R958

Entry history

Integrated into UniProtKB/TrEMBL:	February 6, 2007
Last sequence update:	February 6, 2007
Last modified:	May 1, 2013
This is version 45 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)