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A1R8X2 (A1R8X2_ARTAT) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 52. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
6-phosphofructokinase HAMAP-Rule MF_00339
Short name=Phosphofructokinase HAMAP-Rule MF_00339
EC=2.7.1.11 HAMAP-Rule MF_00339
Alternative name(s):
Phosphohexokinase HAMAP-Rule MF_00339
Gene names
Name:pfkA HAMAP-Rule MF_00339 EMBL ABM09472.1
Ordered Locus Names:AAur_2976 EMBL ABM09472.1
OrganismArthrobacter aurescens (strain TC1) [Complete proteome] [HAMAP] EMBL ABM09472.1
Taxonomic identifier290340 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Micrococcineae › Micrococcaceae › Arthrobacter ›

Protein attributes

Sequence length341 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + D-fructose 6-phosphate = ADP + D-fructose 1,6-bisphosphate. HAMAP-Rule MF_00339

Pathway

Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 3/4. HAMAP-Rule MF_00339

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00339.

Sequence similarities

Belongs to the phosphofructokinase family. HAMAP-Rule MF_00339

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Nucleotide binding20 – 245ATP By similarity HAMAP-Rule MF_00339
Nucleotide binding154 – 1585ATP By similarity HAMAP-Rule MF_00339
Nucleotide binding171 – 18717ATP By similarity HAMAP-Rule MF_00339

Sites

Active site1271Proton acceptor By similarity HAMAP-Rule MF_00339
Binding site1621Substrate By similarity HAMAP-Rule MF_00339
Binding site2651Substrate By similarity HAMAP-Rule MF_00339
Binding site2711Substrate By similarity HAMAP-Rule MF_00339
Binding site2741Substrate By similarity HAMAP-Rule MF_00339

Sequences

Sequence LengthMass (Da)Tools
A1R8X2 [UniParc].

Last modified February 6, 2007. Version 1.
Checksum: 9EFBE3D10FA5471A

FASTA34136,246
        10         20         30         40         50         60 
MKIGILTSGG DCPGLNAVIR GSVLKGIAIH GQEFVGFRDG WRGVVEGDVI DIPRTMVRGI 

        70         80         90        100        110        120 
AKQGGTILGT SRTNPFENGG GPDVIKAHME RLGIDAIIAI GGEGTLAAAK RLTDAGLKIV 

       130        140        150        160        170        180 
GVPKTVDNDL DATDYTFGFD TAVQIATEAI DRLRTTGESH HRCMIAEVMG RHVGWIALHA 

       190        200        210        220        230        240 
GMAAGAHAIL IPEQKASIEQ ITEWVKEAHD RGRAPLVVVA EGFVPDHMES PHSERGLDTF 

       250        260        270        280        290        300 
GRPRLGGIAD QLAPEIEART GIETRATILG HIQRGGVPTA YDRVLATRLG MAAIDSVVEG 

       310        320        330        340 
RWGTMVALKG TDISHVGFEE ALGKLKTVPQ HRYDEASVLF G

« Hide

References

[1]"Secrets of soil survival revealed by the genome sequence of Arthrobacter aurescens TC1."
Mongodin E.F., Shapir N., Daugherty S.C., DeBoy R.T., Emerson J.B., Shvartsbeyn A., Radune D., Vamathevan J., Riggs F., Grinberg V., Khouri H.M., Wackett L.P., Nelson K.E., Sadowsky M.J.
PLoS Genet. 2:e214-e214(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: TC1 EMBL ABM09472.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000474 Genomic DNA. Translation: ABM09472.1.
RefSeqYP_948684.1. NC_008711.1.

3D structure databases

ProteinModelPortalA1R8X2.
ModBaseSearch...

Protein-protein interaction databases

STRING290340.AAur_2976.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABM09472; ABM09472; AAur_2976.
GeneID4641018.
KEGGaau:AAur_2976.
PATRIC20981436. VBIArtAur67810_3025.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0205.
HOGENOMHOG000248869.
KOK00850.
OMASRFSIIV.
ProtClustDBCLSK928283.

Enzyme and pathway databases

BioCycAAUR290340:GI59-3559-MONOMER.
UniPathwayUPA00109; UER00182.

Family and domain databases

HAMAPMF_00339. Phosphofructokinase.
InterProIPR012003. ATP_PFK_prok.
IPR012829. PFK.
IPR022953. Phosphofructokinase.
IPR015912. Phosphofructokinase_CS.
IPR000023. Phosphofructokinase_dom.
[Graphical view]
PfamPF00365. PFK. 1 hit.
[Graphical view]
PIRSFPIRSF000532. ATP_PFK_prok. 1 hit.
PRINTSPR00476. PHFRCTKINASE.
SUPFAMSSF53784. Ppfruckinase. 1 hit.
TIGRFAMsTIGR02483. PFK_mixed. 1 hit.
PROSITEPS00433. PHOSPHOFRUCTOKINASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA1R8X2_ARTAT
AccessionPrimary (citable) accession number: A1R8X2
Entry history
Integrated into UniProtKB/TrEMBL: February 6, 2007
Last sequence update: February 6, 2007
Last modified: May 1, 2013
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info