A1R8T3 (RL5_ARTAT) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
50S ribosomal protein L5

Gene names

Name:	rplE
Ordered Locus Names:	AAur_2936

Organism

Arthrobacter aurescens (strain TC1) [Complete proteome] [HAMAP]

Taxonomic identifier

290340 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Micrococcineae › Micrococcaceae › Arthrobacter

Protein attributes

Sequence length	192 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs By similarity. HAMAP MF_01333_B
Subunit structure	Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome By similarity.
Sequence similarities	Belongs to the ribosomal protein L5P family.

Ontologies

Keywords
Ligand	RNA-binding rRNA-binding tRNA-binding
Molecular function	Ribonucleoprotein Ribosomal protein
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	translation Inferred from electronic annotation. Source: InterPro
Cellular component	ribosome Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	rRNA binding Inferred from electronic annotation. Source: UniProtKB-KW structural constituent of ribosome Inferred from electronic annotation. Source: InterPro tRNA binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 192	192	50S ribosomal protein L5 HAMAP MF_01333_B		PRO_1000166105

Sequences

	Sequence		Length	Mass (Da)
	A1R8T3 [UniParc]. Last modified February 6, 2007. Version 1. Checksum: 069B01173AB47FE4	FASTA	192	21,499
	10 20 30 40 50 60 MTETLETPVK IVPRLKTKYA ETIKKSLQDE FSYANVNQVP RLVKVVVNMG VGDAAKDSKL 70 80 90 100 110 120 IDGAVRDLTL ITGQKPQVTK ARKSIAQFKL REGMPIGAHA TLRGDRMWEF VDRLVSLALP 130 140 150 160 170 180 RIRDFRGLNG KQFDGNGNYT FGLTEQVMFH EIDQDSIDRV RGMDITVVTT AKTDDEGRAL 190 LKALGFPFKT EN

References

[1]

"Secrets of soil survival revealed by the genome sequence of Arthrobacter aurescens TC1." Mongodin E.F., Shapir N., Daugherty S.C., DeBoy R.T., Emerson J.B., Shvartzbeyn A., Radune D., Vamathevan J., Riggs F., Grinberg V., Khouri H.M., Wackett L.P., Nelson K.E., Sadowsky M.J. PLoS Genet. 2:2094-2106(2006) [PubMed: 17194220] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: TC1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000474 Genomic DNA. Translation: ABM09858.1.
RefSeq	YP_948645.1. NC_008711.1.
3D structure databases
ProteinModelPortal	A1R8T3.
SMR	A1R8T3. Positions 12-189.
ModBase	Search...
Protein-protein interaction databases
STRING	A1R8T3.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4640644.
GenomeReviews	Gene locus AAur_2936 in contig CP000474_GR.
KEGG	aau:AAur_2936.
PATRIC	20981356. VBIArtAur67810_2986.
TIGR	AAur_2936.
Phylogenomic databases
eggNOG	COG0094.
HOGENOM	HBG592167.
OMA	RQGMPIG.
ProtClustDB	PRK00010.
Enzyme and pathway databases
BioCyc	AAUR290340:AAUR_2936-MONOMER.
Family and domain databases
HAMAP	MF_01333_B. Ribosomal_L5_B. [Tree]
InterPro	IPR002132. Ribosomal_L5. IPR020930. Ribosomal_L5_bac-type. IPR022803. Ribosomal_L5_domain. [Graphical view]
Gene3D	G3DSA:3.30.1440.10. Ribosomal_L5. 1 hit.
KO	K02931.
PANTHER	PTHR11994. Ribosomal_L5. 1 hit.
Pfam	PF00281. Ribosomal_L5. 1 hit. PF00673. Ribosomal_L5_C. 1 hit. [Graphical view]
PIRSF	PIRSF002161. Ribosomal_L5. 1 hit.
SUPFAM	SSF55282. Ribosomal_L5. 1 hit.
PROSITE	PS00358. RIBOSOMAL_L5. False negative. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

RL5_ARTAT

Accession

Primary (citable) accession number: A1R8T3

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 28, 2009
Last sequence update:	February 6, 2007
Last modified:	December 14, 2011
This is version 36 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program