A1R8N0 (GCP_ARTAT) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable tRNA threonylcarbamoyladenosine biosynthesis protein Gcp

Alternative name(s):
t(6)A37 threonylcarbamoyladenosine biosynthesis protein

Gene names

Name:	gcp
Ordered Locus Names:	AAur_2883

Organism

Arthrobacter aurescens (strain TC1) [Complete proteome] [HAMAP]

Taxonomic identifier

290340 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Micrococcineae › Micrococcaceae › Arthrobacter

Protein attributes

Sequence length	368 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t6A37) in tRNAs that read codons beginning with adenine By similarity. HAMAP MF_01445
Subcellular location	Cytoplasm Potential HAMAP MF_01445.
Sequence similarities	Belongs to the KAE1 / YgjD family.

Ontologies

Keywords
Biological process	tRNA processing
Cellular component	Cytoplasm
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	proteolysis Inferred from electronic annotation. Source: InterPro tRNA processing Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	metalloendopeptidase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 368	368	Probable tRNA threonylcarbamoyladenosine biosynthesis protein Gcp HAMAP MF_01445		PRO_0000303257

Sequences

	Sequence		Length	Mass (Da)
	A1R8N0 [UniParc]. Last modified February 6, 2007. Version 1. Checksum: 2B3DA8282E043407	FASTA	368	37,580
	10 20 30 40 50 60 MLGIESSCDE TGVGIVRGTT LLTNTVSSSM DEHVRFGGVI PEIASRAHLD AFVPTLQESL 70 80 90 100 110 120 QEAGVTLEDI DAIAVTSGPG LAGALMVGVC AAKALAVATG KPLYAINHLV AHVGVGLLDG 130 140 150 160 170 180 NRVSEGKHDA VAAAGLGAGK LPENLGALLV SGGHTEILRI RSITDDVELL GSTIDDAAGE 190 200 210 220 230 240 AYDKVARILG LGYPGGPAID KLAHQGNPKS IRFPRGLTQP KYMGTAEEKG PHRYDWSFSG 250 260 270 280 290 300 LKTAVARCVE QFEARGEEVP VADIAAAFQE AVVDVISSKA VLACKEHGIT DVLLGGGVAA 310 320 330 340 350 360 NSRLRELTGQ RCASAGITLH VPPLGLCTDN GAMVAALGAQ LIMAGISPSG VSFAPDSSMP VTTVSVPA

References

[1]

"Secrets of soil survival revealed by the genome sequence of Arthrobacter aurescens TC1." Mongodin E.F., Shapir N., Daugherty S.C., DeBoy R.T., Emerson J.B., Shvartzbeyn A., Radune D., Vamathevan J., Riggs F., Grinberg V., Khouri H.M., Wackett L.P., Nelson K.E., Sadowsky M.J. PLoS Genet. 2:2094-2106(2006) [PubMed: 17194220] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: TC1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000474 Genomic DNA. Translation: ABM08610.1.
RefSeq	YP_948592.1. NC_008711.1.
3D structure databases
ProteinModelPortal	A1R8N0.
ModBase	Search...
Protein-protein interaction databases
STRING	A1R8N0.
Protein family/group databases
MEROPS	M22.A01.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4641363.
GenomeReviews	Gene locus AAur_2883 in contig CP000474_GR.
KEGG	aau:AAur_2883.
PATRIC	20981246. VBIArtAur67810_2931.
TIGR	AAur_2883.
Phylogenomic databases
eggNOG	COG0533.
HOGENOM	HBG304663.
OMA	PLYGVNH.
ProtClustDB	PRK09604.
Enzyme and pathway databases
BioCyc	AAUR290340:AAUR_2883-MONOMER.
Family and domain databases
HAMAP	MF_01445. gcp. [Tree]
InterPro	IPR022450. Pept_M22_O-sialoglycopept. IPR000905. Peptidase_M22. IPR017861. Peptidase_M22_subgr. [Graphical view]
KO	K01409.
Pfam	PF00814. Peptidase_M22. 1 hit. [Graphical view]
PRINTS	PR00789. OSIALOPTASE.
TIGRFAMs	TIGR03723. Bact_gcp. 1 hit. TIGR00329. Gcp_kae1. 1 hit.
PROSITE	PS01016. GLYCOPROTEASE. False negative. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GCP_ARTAT

Accession

Primary (citable) accession number: A1R8N0

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 11, 2007
Last sequence update:	February 6, 2007
Last modified:	December 14, 2011
This is version 40 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program