A1R8A0 (A1R8A0_ARTAT) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Delta-aminolevulinic acid dehydratase EMBL ABM09974.1
EC=4.2.1.24 EMBL ABM09974.1

Gene names

Name:	hemB EMBL ABM09974.1
Ordered Locus Names:	AAur_2749

Organism

Arthrobacter aurescens (strain TC1) [Complete proteome] [HAMAP] EMBL ABM09974.1

Taxonomic identifier

290340 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Micrococcineae › Micrococcaceae › Arthrobacter

Protein attributes

Sequence length	326 AA.
Sequence status	Complete.
Protein existence	Predicted

Ontologies

Keywords
Ligand	Magnesium PIRSR PIRSR001415-5 Metal-binding PIRSR PIRSR001415-5
Molecular function	Lyase EMBL ABM09974.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	porphyrin-containing compound biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW porphobilinogen synthase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	197	1	Schiff-base intermediate with substrate By similarity PIRSR PIRSR001415-1
	Active site	249	1	Schiff-base intermediate with substrate By similarity PIRSR PIRSR001415-1
	Metal binding	234	1	Magnesium By similarity PIRSR PIRSR001415-5
	Binding site	207	1	Substrate 1 By similarity PIRSR PIRSR001415-2
	Binding site	218	1	Substrate 1 By similarity PIRSR PIRSR001415-2
	Binding site	275	1	Substrate 2 By similarity PIRSR PIRSR001415-2
	Binding site	314	1	Substrate 2 By similarity PIRSR PIRSR001415-2

Sequences

	Sequence		Length	Mass (Da)
	A1R8A0 [UniParc]. Last modified February 6, 2007. Version 1. Checksum: 71A25F9EA8D8CBA0	FASTA	326	34,952
	10 20 30 40 50 60 MSFPNHRPRR LRTTPAMRRL TAENRLAPAD LILPAFIREG LTEPSPISSM PGVVQHTTES 70 80 90 100 110 120 LKRAAAEAVE LGVGGIMLFG VPAVRDAQGT ASLDPDGVLN KAIRDVKAEV GDDLVIMGDV 130 140 150 160 170 180 CLDEFTDHGH CGVLDSEGYV DNDATLEIYG RMAVAQADAG AHVLGPSGMM DGQIAVIRQA 190 200 210 220 230 240 LEESGHKNTA VLAYAAKYAS AFYGPFREAV DSQLKGDRRT YQMDAANRRE AILEVELDLE 250 260 270 280 290 300 EGADMVMVKP AMSYLDILAD VAAMSPVPVS AYQISGEYAM IEAAAANGWI DRRGAITESV 310 320 LGIKRAGADT VLTYWASELA GWLKES

References

[1]

"Secrets of soil survival revealed by the genome sequence of Arthrobacter aurescens TC1." Mongodin E.F., Shapir N., Daugherty S.C., DeBoy R.T., Emerson J.B., Shvartzbeyn A., Radune D., Vamathevan J., Riggs F., Grinberg V., Khouri H.M., Wackett L.P., Nelson K.E., Sadowsky M.J. PLoS Genet. 2:2094-2106(2006) [PubMed: 17194220] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000474 Genomic DNA. Translation: ABM09974.1.
RefSeq	YP_948462.1. NC_008711.1.
3D structure databases
ProteinModelPortal	A1R8A0.
ModBase	Search...
Protein-protein interaction databases
STRING	A1R8A0.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4640262.
GenomeReviews	Gene locus AAur_2749 in contig CP000474_GR.
KEGG	aau:AAur_2749.
PATRIC	20980964. VBIArtAur67810_2791.
TIGR	AAur_2749.
Phylogenomic databases
eggNOG	COG0113.
HOGENOM	HBG285270.
OMA	FTSHGHD.
ProtClustDB	PRK09283.
Family and domain databases
InterPro	IPR013785. Aldolase_TIM. IPR001731. Porphobilinogen_synth. [Graphical view]
Gene3D	G3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
KO	K01698.
PANTHER	PTHR11458. AlaD_dehydratase. 1 hit.
Pfam	PF00490. ALAD. 1 hit. [Graphical view]
PIRSF	PIRSF001415. Porphbilin_synth. 1 hit.
PRINTS	PR00144. DALDHYDRTASE.
SMART	SM01004. ALAD. 1 hit. [Graphical view]
PROSITE	PS00169. D_ALA_DEHYDRATASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A1R8A0_ARTAT

Accession

Primary (citable) accession number: A1R8A0

Entry history

Integrated into UniProtKB/TrEMBL:	February 6, 2007
Last sequence update:	February 6, 2007
Last modified:	January 25, 2012
This is version 38 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)