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A1R7X2

- SYR_ARTAT

UniProt

A1R7X2 - SYR_ARTAT

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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Arthrobacter aurescens (strain TC1)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

  1. arginine-tRNA ligase activity Source: UniProtKB-HAMAP
  2. ATP binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. arginyl-tRNA aminoacylation Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Aminoacyl-tRNA synthetase, Ligase

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciAAUR290340:GI59-2613-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)
Alternative name(s):
Arginyl-tRNA synthetaseUniRule annotation
Short name:
ArgRSUniRule annotation
Gene namesi
Name:argSUniRule annotation
Ordered Locus Names:AAur_2614
OrganismiArthrobacter aurescens (strain TC1)
Taxonomic identifieri290340 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesMicrococcineaeMicrococcaceaeArthrobacter
ProteomesiUP000000637: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 549549Arginine--tRNA ligasePRO_1000017985Add
BLAST

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi290340.AAur_2614.

Structurei

3D structure databases

ProteinModelPortaliA1R7X2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi132 – 14211"HIGH" regionAdd
BLAST

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0018.
HOGENOMiHOG000247214.
KOiK01887.
OMAiMEHMGFG.
OrthoDBiEOG6JB13C.

Family and domain databases

Gene3Di1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPiMF_00123. Arg_tRNA_synth.
InterProiIPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERiPTHR11956. PTHR11956. 1 hit.
PfamiPF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view]
PRINTSiPR01038. TRNASYNTHARG.
SMARTiSM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMiSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsiTIGR00456. argS. 1 hit.
PROSITEiPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A1R7X2-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MTPEELSAAI SACLKDAVST GEIALTESAV PDAVRVERPK NRDHGDWATN
60 70 80 90 100
IALQLSKQAG MNPREFAGIL SNHLQGIPGV TGVEIAGPGF LNITVDAATA
110 120 130 140 150
GALAKAIVEA GASYGTNQAL AGRVVNMEFV SANPTGPLHI GHTRWAALGD
160 170 180 190 200
AIARVLRASG ADVTAEYYIN DAGSQMNVFA NSVLSRLHGR GVPEGGYPGE
210 220 230 240 250
YIRELGDEVL KAHPGIRELT DEAALPVIRA AAYEAQMSDI KTTLAEFGVE
260 270 280 290 300
FDVFFSEKEL HDAGAIESAV ARLREQGHVF DDGGAVWLRT TDFGDDKDRV
310 320 330 340 350
MIRANGEPTY FAADAAYYLS KKDRGFTEKI YLLGADHHGY INRLKAIAAC
360 370 380 390 400
AGDDPEVNIE VLIGQLVSVN GAKLSKRAGN IIELKDLISW LGKDAVRYSL
410 420 430 440 450
ARFPADSPLT LDPELLKKHS NENPVFYVQY AHARSRGTAR NAAEAGVDRS
460 470 480 490 500
VFDASLLDHA TENELLSYLG SYPSIVAKAA ELREPHRVAR HLEVIAGAYH
510 520 530 540
RWYDACRVSP QGEEPVLDVN RTRLWLNDAT SQVLANGLEL LGVSAPERM
Length:549
Mass (Da):59,204
Last modified:February 6, 2007 - v1
Checksum:i39DF2C0707751AFB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000474 Genomic DNA. Translation: ABM06929.1.
RefSeqiYP_948334.1. NC_008711.1.

Genome annotation databases

EnsemblBacteriaiABM06929; ABM06929; AAur_2614.
GeneIDi4637309.
KEGGiaau:AAur_2614.
PATRICi20980672. VBIArtAur67810_2648.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000474 Genomic DNA. Translation: ABM06929.1 .
RefSeqi YP_948334.1. NC_008711.1.

3D structure databases

ProteinModelPortali A1R7X2.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 290340.AAur_2614.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABM06929 ; ABM06929 ; AAur_2614 .
GeneIDi 4637309.
KEGGi aau:AAur_2614.
PATRICi 20980672. VBIArtAur67810_2648.

Phylogenomic databases

eggNOGi COG0018.
HOGENOMi HOG000247214.
KOi K01887.
OMAi MEHMGFG.
OrthoDBi EOG6JB13C.

Enzyme and pathway databases

BioCyci AAUR290340:GI59-2613-MONOMER.

Family and domain databases

Gene3Di 1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPi MF_00123. Arg_tRNA_synth.
InterProi IPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view ]
PANTHERi PTHR11956. PTHR11956. 1 hit.
Pfami PF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view ]
PRINTSi PR01038. TRNASYNTHARG.
SMARTi SM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view ]
SUPFAMi SSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsi TIGR00456. argS. 1 hit.
PROSITEi PS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: TC1.

Entry informationi

Entry nameiSYR_ARTAT
AccessioniPrimary (citable) accession number: A1R7X2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: February 6, 2007
Last modified: October 29, 2014
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3