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A1R7X2 (SYR_ARTAT) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 54. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Arginine--tRNA ligase

EC=6.1.1.19
Alternative name(s):
Arginyl-tRNA synthetase
Short name=ArgRS
Gene names
Name:argS
Ordered Locus Names:AAur_2614
OrganismArthrobacter aurescens (strain TC1) [Complete proteome] [HAMAP]
Taxonomic identifier290340 [NCBI]
Taxonomic lineageBacteriaActinobacteriaActinobacteridaeActinomycetalesMicrococcineaeMicrococcaceaeArthrobacter

Protein attributes

Sequence length549 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg). HAMAP-Rule MF_00123

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00123

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00123.

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionAminoacyl-tRNA synthetase
Ligase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processarginyl-tRNA aminoacylation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

arginine-tRNA ligase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 549549Arginine--tRNA ligase HAMAP-Rule MF_00123
PRO_1000017985

Regions

Motif132 – 14211"HIGH" region HAMAP-Rule MF_00123

Sequences

Sequence LengthMass (Da)Tools
A1R7X2 [UniParc].

Last modified February 6, 2007. Version 1.
Checksum: 39DF2C0707751AFB

FASTA54959,204
        10         20         30         40         50         60 
MTPEELSAAI SACLKDAVST GEIALTESAV PDAVRVERPK NRDHGDWATN IALQLSKQAG 

        70         80         90        100        110        120 
MNPREFAGIL SNHLQGIPGV TGVEIAGPGF LNITVDAATA GALAKAIVEA GASYGTNQAL 

       130        140        150        160        170        180 
AGRVVNMEFV SANPTGPLHI GHTRWAALGD AIARVLRASG ADVTAEYYIN DAGSQMNVFA 

       190        200        210        220        230        240 
NSVLSRLHGR GVPEGGYPGE YIRELGDEVL KAHPGIRELT DEAALPVIRA AAYEAQMSDI 

       250        260        270        280        290        300 
KTTLAEFGVE FDVFFSEKEL HDAGAIESAV ARLREQGHVF DDGGAVWLRT TDFGDDKDRV 

       310        320        330        340        350        360 
MIRANGEPTY FAADAAYYLS KKDRGFTEKI YLLGADHHGY INRLKAIAAC AGDDPEVNIE 

       370        380        390        400        410        420 
VLIGQLVSVN GAKLSKRAGN IIELKDLISW LGKDAVRYSL ARFPADSPLT LDPELLKKHS 

       430        440        450        460        470        480 
NENPVFYVQY AHARSRGTAR NAAEAGVDRS VFDASLLDHA TENELLSYLG SYPSIVAKAA 

       490        500        510        520        530        540 
ELREPHRVAR HLEVIAGAYH RWYDACRVSP QGEEPVLDVN RTRLWLNDAT SQVLANGLEL 


LGVSAPERM 

« Hide

References

[1]"Secrets of soil survival revealed by the genome sequence of Arthrobacter aurescens TC1."
Mongodin E.F., Shapir N., Daugherty S.C., DeBoy R.T., Emerson J.B., Shvartzbeyn A., Radune D., Vamathevan J., Riggs F., Grinberg V., Khouri H.M., Wackett L.P., Nelson K.E., Sadowsky M.J.
PLoS Genet. 2:2094-2106(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: TC1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000474 Genomic DNA. Translation: ABM06929.1.
RefSeqYP_948334.1. NC_008711.1.

3D structure databases

ProteinModelPortalA1R7X2.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING290340.AAur_2614.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABM06929; ABM06929; AAur_2614.
GeneID4637309.
KEGGaau:AAur_2614.
PATRIC20980672. VBIArtAur67810_2648.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0018.
HOGENOMHOG000247214.
KOK01887.
OMAMEHMGFG.
OrthoDBEOG6JB13C.

Enzyme and pathway databases

BioCycAAUR290340:GI59-2613-MONOMER.

Family and domain databases

Gene3D1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPMF_00123. Arg_tRNA_synth.
InterProIPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERPTHR11956. PTHR11956. 1 hit.
PfamPF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view]
PRINTSPR01038. TRNASYNTHARG.
SMARTSM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsTIGR00456. argS. 1 hit.
PROSITEPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSYR_ARTAT
AccessionPrimary (citable) accession number: A1R7X2
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: February 6, 2007
Last modified: May 14, 2014
This is version 54 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Aminoacyl-tRNA synthetases

List of aminoacyl-tRNA synthetase entries