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A1R786 (A1R786_ARTAT) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 43. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Glutamate 5-kinase HAMAP MF_00456
EC=2.7.2.11 HAMAP MF_00456
Alternative name(s):
Gamma-glutamyl kinase HAMAP MF_00456
Gene names
Name:proB HAMAP MF_00456
Ordered Locus Names:AAur_2364
OrganismArthrobacter aurescens (strain TC1) [Complete proteome] [HAMAP] EMBL ABM09301.1
Taxonomic identifier290340 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Micrococcineae › Micrococcaceae › Arthrobacter

Protein attributes

Sequence length394 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5-oxoproline By similarity. SAAS SAAS011529 HAMAP MF_00456

Catalytic activity

ATP + L-glutamate = ADP + L-glutamate 5-phosphate. HAMAP MF_00456 SAAS SAAS011529

Pathway

Amino-acid biosynthesis; L-proline biosynthesis; L-glutamate 5-semialdehyde from L-glutamate: step 1/2. HAMAP MF_00456 SAAS SAAS011529

Subcellular location

Cytoplasm By similarity HAMAP MF_00456 SAAS SAAS011529.

Sequence similarities

Belongs to the glutamate 5-kinase family. HAMAP MF_00456

Contains 1 PUA domain. HAMAP MF_00456 SAAS SAAS011529

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Domain292 – 37079PUA By similarity HAMAP MF_00456

Sequences

Sequence LengthMass (Da)Tools
A1R786 [UniParc].

Last modified February 6, 2007. Version 1.
Checksum: 34D9CEAD8B209B87

FASTA39441,167
        10         20         30         40         50         60 
MMTTKTVDAP DTAEGLERQA LATAKRIVVK VGSSSLTSIK GGISEKSLTG LVNALAEKRN 

        70         80         90        100        110        120 
AGTEIILVSS GAIAAGLAPL GLAKRPKDLA TQQAAASVGQ GLLMARYTQA FNAHGVTVSQ 

       130        140        150        160        170        180 
VLLTADDLMR RTQHTNAFRA LDRLLNLGVV PVVNENDTVA THEIRFGDND RLAALVAHLV 

       190        200        210        220        230        240 
RADALVLLSD VDALYDGPPS QGAQRIPLVR GPQDLEDVTI GKAGKAGVGT GGMMTKVEAA 

       250        260        270        280        290        300 
SIAAGSGIHA LVTSTANAAA ALAGQDVGTW FAVNGNRKPV RLLWLAHLAT VHGRLMLDDG 

       310        320        330        340        350        360 
AVKAVRDRHR SLLPAGISDI SGDFEAGDPI EMVAHDGTVV ARGLVNYSSE ELPRMLGRTT 

       370        380        390 
QELGQAMGRG YDREVVHVDD LVLLRASRSS KLGA

« Hide

References

[1]"Secrets of soil survival revealed by the genome sequence of Arthrobacter aurescens TC1."
Mongodin E.F., Shapir N., Daugherty S.C., DeBoy R.T., Emerson J.B., Shvartzbeyn A., Radune D., Vamathevan J., Riggs F., Grinberg V., Khouri H.M., Wackett L.P., Nelson K.E., Sadowsky M.J.
PLoS Genet. 2:2094-2106(2006) [PubMed: 17194220] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000474 Genomic DNA. Translation: ABM09301.1.
RefSeqYP_948098.1. NC_008711.1.

3D structure databases

ProteinModelPortalA1R786.
ModBaseSearch...

Protein-protein interaction databases

STRINGA1R786.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4639835.
GenomeReviewsGene locus AAur_2364 in contig CP000474_GR.
KEGGaau:AAur_2364.
PATRIC20980154. VBIArtAur67810_2399.
TIGRAAur_2364.

Phylogenomic databases

eggNOGCOG0263.
HOGENOMHBG507643.
OMATFGDNDM.
ProtClustDBPRK05429.

Family and domain databases

HAMAPMF_00456. ProB.
[Tree]
InterProIPR001048. Asp/Glu/Uridylate_kinase.
IPR001057. Glu/AcGlu_kinase.
IPR011529. Glu_5kinase.
IPR005715. Glu_5kinase/COase_Synthase.
IPR019797. Glutamate_5-kinase_CS.
IPR002478. PUA.
IPR015947. PUA-like_domain.
[Graphical view]
Gene3DG3DSA:3.40.1160.10. Aa_kinase. 1 hit.
KOK00931.
PfamPF00696. AA_kinase. 1 hit.
PF01472. PUA. 1 hit.
[Graphical view]
PIRSFPIRSF000729. GK. 1 hit.
PRINTSPR00474. GLU5KINASE.
SMARTSM00359. PUA. 1 hit.
[Graphical view]
SUPFAMSSF53633. Aa_kinase. 1 hit.
SSF88697. PUA-like. 1 hit.
TIGRFAMsTIGR01027. ProB. 1 hit.
PROSITEPS00902. GLUTAMATE_5_KINASE. 1 hit.
PS50890. PUA. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA1R786_ARTAT
AccessionPrimary (citable) accession number: A1R786
Entry history
Integrated into UniProtKB/TrEMBL: February 6, 2007
Last sequence update: February 6, 2007
Last modified: December 14, 2011
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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