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A1R705 (AROC_ARTAT) Reviewed, UniProtKB/Swiss-Prot

Last modified December 14, 2011. Version 34. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Chorismate synthase
EC=4.2.3.5
Alternative name(s):
5-enolpyruvylshikimate-3-phosphate phospholyase
Gene names
Name:aroC
Ordered Locus Names:AAur_2277
OrganismArthrobacter aurescens (strain TC1) [Complete proteome] [HAMAP]
Taxonomic identifier290340 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Micrococcineae › Micrococcaceae › Arthrobacter

Protein attributes

Sequence length399 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

5-O-(1-carboxyvinyl)-3-phosphoshikimate = chorismate + phosphate. HAMAP MF_00300

Cofactor

Reduced flavin By similarity. HAMAP MF_00300

Pathway

Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 7/7. HAMAP MF_00300

Subunit structure

Homotetramer By similarity. HAMAP MF_00300

Sequence similarities

Belongs to the chorismate synthase family.

Sequence caution

The sequence ABM09327.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Aromatic amino acid biosynthesis
   Molecular functionLyase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processaromatic amino acid family biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular functionchorismate synthase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 399399Chorismate synthase HAMAP MF_00300
PRO_0000322386

Sequences

Sequence LengthMass (Da)Tools
A1R705 [UniParc].

Last modified February 26, 2008. Version 2.
Checksum: E42C5AA560585FC9

FASTA39942,361
        10         20         30         40         50         60 
MLRWLTAGES HGPALIGIVE GVPAGVELTS GQIRDALARR RLGYGRGARM KFEQDEVTIM 

        70         80         90        100        110        120 
GGVRHGLTQG GPVAIQVGNT EWPKWEQIMS ADPVDPEVLA DQARNAPLTR PRPGHADFTG 

       130        140        150        160        170        180 
MQKYGFDEAR PVLERASARE TATRVALGTV AAQFLKQLGI ELVSHTVSIA SVTVPEGRPL 

       190        200        210        220        230        240 
PLPKDVIALD ADPLRCFDRE TSNAMVAEVD AAHKEGETLG GVVEVLAYGL PPGLGSYVHW 

       250        260        270        280        290        300 
DRRLDSRLAA ALMGIQAIKG VEVGDGFLTA ARRGSAAHDE ILKDENGKIV RQTNRAGGIE 

       310        320        330        340        350        360 
GGMSIGEVLR VRAAMKPIAT VPRALRTIDV STGEPAKAHH QRSDVCAVPA AGVVAEAMVA 

       370        380        390 
LVLAEAVAEK FGGDSVPETQ RNLQSYLESI PATLDSVGR

« Hide

References

[1]"Secrets of soil survival revealed by the genome sequence of Arthrobacter aurescens TC1."
Mongodin E.F., Shapir N., Daugherty S.C., DeBoy R.T., Emerson J.B., Shvartzbeyn A., Radune D., Vamathevan J., Riggs F., Grinberg V., Khouri H.M., Wackett L.P., Nelson K.E., Sadowsky M.J.
PLoS Genet. 2:2094-2106(2006) [PubMed: 17194220] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: TC1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000474 Genomic DNA. Translation: ABM09327.1. Different initiation.
RefSeqYP_948017.1. NC_008711.1.

3D structure databases

ProteinModelPortalA1R705.
SMRA1R705. Positions 1-390.
ModBaseSearch...

Protein-protein interaction databases

STRINGA1R705.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4639476.
GenomeReviewsGene locus AAur_2277 in contig CP000474_GR.
KEGGaau:AAur_2277.
PATRIC20979976. VBIArtAur67810_2312.
TIGRAAur_2277.

Phylogenomic databases

eggNOGCOG0082.
HOGENOMHBG292336.
ProtClustDBPRK05382.

Enzyme and pathway databases

BioCycAAUR290340:AAUR_2277-MONOMER.

Family and domain databases

HAMAPMF_00300. Chorismate_synth.
[Tree]
InterProIPR000453. Chorismate_synth.
IPR020541. Chorismate_synthase_CS.
[Graphical view]
KOK01736.
PANTHERPTHR21085. Chorismate_synth. 1 hit.
PfamPF01264. Chorismate_synt. 1 hit.
[Graphical view]
PIRSFPIRSF001456. Chorismate_synth. 1 hit.
SUPFAMSSF103263. Chorismate_synth. 1 hit.
TIGRFAMsTIGR00033. AroC. 1 hit.
PROSITEPS00787. CHORISMATE_SYNTHASE_1. 1 hit.
PS00788. CHORISMATE_SYNTHASE_2. 1 hit.
PS00789. CHORISMATE_SYNTHASE_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameAROC_ARTAT
AccessionPrimary (citable) accession number: A1R705
Entry history
Integrated into UniProtKB/Swiss-Prot: February 26, 2008
Last sequence update: February 26, 2008
Last modified: December 14, 2011
This is version 34 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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