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A1R6S4 (A1R6S4_ARTAT) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 31. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Peptide deformylase 2 HAMAP MF_00163
Short name=PDF 2 HAMAP MF_00163
EC=3.5.1.88 HAMAP MF_00163
Alternative name(s):
Polypeptide deformylase 2 HAMAP MF_00163
Gene names
Name:def EMBL ABM06528.1
Synonyms:def2 HAMAP MF_00163
Ordered Locus Names:AAur_2194
OrganismArthrobacter aurescens (strain TC1) [Complete proteome] [HAMAP] EMBL ABM06528.1
Taxonomic identifier290340 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Micrococcineae › Micrococcaceae › Arthrobacter

Protein attributes

Sequence length224 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions By similarity. HAMAP MF_00163

Catalytic activity

Formyl-L-methionyl peptide + H2O = formate + methionyl peptide. HAMAP MF_00163 SAAS SAAS000181

Cofactor

Binds 1 Fe2+ ion By similarity. HAMAP MF_00163

Sequence similarities

Belongs to the polypeptide deformylase family. HAMAP MF_00163

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site1801 By similarity HAMAP MF_00163
Metal binding1371Iron By similarity HAMAP MF_00163
Metal binding1791Iron By similarity HAMAP MF_00163
Metal binding1831Iron By similarity HAMAP MF_00163

Sequences

Sequence LengthMass (Da)Tools
A1R6S4 [UniParc].

Last modified February 6, 2007. Version 1.
Checksum: 3441586382D66F80

FASTA22425,014
        10         20         30         40         50         60 
MTHQPPPEAT SPATDYNPTQ IRDAVRRLLD AEALPSIVQA GHPVLRQLAA PYDGQIDDAE 

        70         80         90        100        110        120 
LAAFLERMKE VMHDAPGVGL AAPQLGIPLQ LAVLEDKYEV DPESAAVRHR EPLEFFAIVN 

       130        140        150        160        170        180 
PQYRPLGTET ASFYEGCLSV SGYQAVVTRH RNVELRYTNP AGEPVEEWFS GWQARIVQHE 

       190        200        210        220 
TDHLRGILYL DRAELRSLSS NAEHSARWFA PNIDEARRAL GFLP

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References

[1]"Secrets of soil survival revealed by the genome sequence of Arthrobacter aurescens TC1."
Mongodin E.F., Shapir N., Daugherty S.C., DeBoy R.T., Emerson J.B., Shvartzbeyn A., Radune D., Vamathevan J., Riggs F., Grinberg V., Khouri H.M., Wackett L.P., Nelson K.E., Sadowsky M.J.
PLoS Genet. 2:2094-2106(2006) [PubMed: 17194220] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000474 Genomic DNA. Translation: ABM06528.1.
RefSeqYP_947936.1. NC_008711.1.

3D structure databases

ProteinModelPortalA1R6S4.
ModBaseSearch...

Protein-protein interaction databases

STRINGA1R6S4.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4641219.
GenomeReviewsGene locus AAur_2194 in contig CP000474_GR.
KEGGaau:AAur_2194.
PATRIC20979802. VBIArtAur67810_2225.
TIGRAAur_2194.

Phylogenomic databases

eggNOGCOG0242.
HOGENOMHBG665227.
OMAGWQARIV.
ProtClustDBPRK00150.

Family and domain databases

HAMAPMF_00163. Pep_deformylase.
[Tree]
InterProIPR000181. Fmet_deformylase.
IPR023635. Peptide_deformylase.
[Graphical view]
Gene3DG3DSA:3.90.45.10. Fmet_deformylase. 1 hit.
KOK01462.
PANTHERPTHR10458. Fmet_deformylase. 1 hit.
PfamPF01327. Pep_deformylase. 1 hit.
[Graphical view]
PIRSFPIRSF004749. Pep_def. 1 hit.
PRINTSPR01576. PDEFORMYLASE.
SUPFAMSSF56420. Fmet_deformylase. 1 hit.
ProtoNetSearch...

Entry information

Entry nameA1R6S4_ARTAT
AccessionPrimary (citable) accession number: A1R6S4
Entry history
Integrated into UniProtKB/TrEMBL: February 6, 2007
Last sequence update: February 6, 2007
Last modified: December 14, 2011
This is version 31 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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