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A1R6H1

- PGK_ARTAT

UniProt

A1R6H1 - PGK_ARTAT

Protein

Phosphoglycerate kinase

Gene

pgk

Organism
Arthrobacter aurescens (strain TC1)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 55 (01 Oct 2014)
      Sequence version 1 (06 Feb 2007)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate.UniRule annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei39 – 391SubstrateUniRule annotation
    Binding sitei121 – 1211SubstrateUniRule annotation
    Binding sitei161 – 1611SubstrateUniRule annotation
    Binding sitei211 – 2111ATPUniRule annotation
    Binding sitei307 – 3071ATP; via carbonyl oxygenUniRule annotation
    Binding sitei338 – 3381ATPUniRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi364 – 3674ATPUniRule annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. phosphoglycerate kinase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. glycolytic process Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Kinase, Transferase

    Keywords - Biological processi

    Glycolysis

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciAAUR290340:GI59-2089-MONOMER.
    UniPathwayiUPA00109; UER00185.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Phosphoglycerate kinaseUniRule annotation (EC:2.7.2.3UniRule annotation)
    Gene namesi
    Name:pgkUniRule annotation
    Ordered Locus Names:AAur_2089
    OrganismiArthrobacter aurescens (strain TC1)
    Taxonomic identifieri290340 [NCBI]
    Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesMicrococcineaeMicrococcaceaeArthrobacter
    ProteomesiUP000000637: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 408408Phosphoglycerate kinasePRO_1000009603Add
    BLAST

    Interactioni

    Subunit structurei

    Monomer.UniRule annotation

    Protein-protein interaction databases

    STRINGi290340.AAur_2089.

    Family & Domainsi

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni24 – 263Substrate bindingUniRule annotation
    Regioni62 – 654Substrate bindingUniRule annotation

    Sequence similaritiesi

    Belongs to the phosphoglycerate kinase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0126.
    HOGENOMiHOG000227107.
    KOiK00927.
    OMAiAGHPVGK.
    OrthoDBiEOG64N9Z0.

    Family and domain databases

    Gene3Di3.40.50.1260. 1 hit.
    3.40.50.1270. 1 hit.
    HAMAPiMF_00145. Phosphoglyc_kinase.
    InterProiIPR001576. Phosphoglycerate_kinase.
    IPR015901. Phosphoglycerate_kinase_C.
    IPR015824. Phosphoglycerate_kinase_N.
    [Graphical view]
    PANTHERiPTHR11406. PTHR11406. 1 hit.
    PfamiPF00162. PGK. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000724. Pgk. 1 hit.
    PRINTSiPR00477. PHGLYCKINASE.
    SUPFAMiSSF53748. SSF53748. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    A1R6H1-1 [UniParc]FASTAAdd to Basket

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    MTSHTLNELI AEGVRGRYIL VRSDLNVPLD GSAVTDDGRI KASLPVLKKL    50
    SDAGARVLVT AHLGRPKGAP EDKYSLKPAA ARLAELADFK VQLANDTVGD 100
    SAKELAAGLQ DGEVLVLENV RFDARETSKD DAERGAFADE LVALTGTNGA 150
    YVDDAFGAVH RKHASVFDVA TRLPSYLGDL VHTEVEVLRK LTTDTQRPYV 200
    VVLGGSKVSD KLAVIDNLLG KADTILVGGG MLFTFLAAAG HKVAGSLLEE 250
    DQIPVVQDYL KRASDAGTSF VIPTDVVVAS RFAADAEHEV VKADAIEDST 300
    FGASGIGLDI GPESAAAFAA QIEGAKTVFW NGPMGVFEFE AFSSGTRAIA 350
    QALTDTVAFT VVGGGDSAAA VRTLGFEDSQ FGHISTGGGA SLEYLEGKEL 400
    PGLSVLDR 408
    Length:408
    Mass (Da):42,688
    Last modified:February 6, 2007 - v1
    Checksum:i26D7A0B88FE2701A
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000474 Genomic DNA. Translation: ABM08929.1.
    RefSeqiYP_947833.1. NC_008711.1.

    Genome annotation databases

    EnsemblBacteriaiABM08929; ABM08929; AAur_2089.
    GeneIDi4638872.
    KEGGiaau:AAur_2089.
    PATRICi20979592. VBIArtAur67810_2121.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000474 Genomic DNA. Translation: ABM08929.1 .
    RefSeqi YP_947833.1. NC_008711.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 290340.AAur_2089.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABM08929 ; ABM08929 ; AAur_2089 .
    GeneIDi 4638872.
    KEGGi aau:AAur_2089.
    PATRICi 20979592. VBIArtAur67810_2121.

    Phylogenomic databases

    eggNOGi COG0126.
    HOGENOMi HOG000227107.
    KOi K00927.
    OMAi AGHPVGK.
    OrthoDBi EOG64N9Z0.

    Enzyme and pathway databases

    UniPathwayi UPA00109 ; UER00185 .
    BioCyci AAUR290340:GI59-2089-MONOMER.

    Family and domain databases

    Gene3Di 3.40.50.1260. 1 hit.
    3.40.50.1270. 1 hit.
    HAMAPi MF_00145. Phosphoglyc_kinase.
    InterProi IPR001576. Phosphoglycerate_kinase.
    IPR015901. Phosphoglycerate_kinase_C.
    IPR015824. Phosphoglycerate_kinase_N.
    [Graphical view ]
    PANTHERi PTHR11406. PTHR11406. 1 hit.
    Pfami PF00162. PGK. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000724. Pgk. 1 hit.
    PRINTSi PR00477. PHGLYCKINASE.
    SUPFAMi SSF53748. SSF53748. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: TC1.

    Entry informationi

    Entry nameiPGK_ARTAT
    AccessioniPrimary (citable) accession number: A1R6H1
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: January 15, 2008
    Last sequence update: February 6, 2007
    Last modified: October 1, 2014
    This is version 55 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3