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A1R6H1 (PGK_ARTAT) Reviewed, UniProtKB/Swiss-Prot

Last modified December 14, 2011. Version 37. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Phosphoglycerate kinase
EC=2.7.2.3
Gene names
Name:pgk
Ordered Locus Names:AAur_2089
OrganismArthrobacter aurescens (strain TC1) [Complete proteome] [HAMAP]
Taxonomic identifier290340 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Micrococcineae › Micrococcaceae › Arthrobacter

Protein attributes

Sequence length408 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate. HAMAP MF_00145

Pathway

Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 2/5. HAMAP MF_00145

Subunit structure

Monomer By similarity. HAMAP MF_00145

Subcellular location

Cytoplasm Potential HAMAP MF_00145.

Sequence similarities

Belongs to the phosphoglycerate kinase family.

Ontologies

Keywords
   Biological processGlycolysis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processglycolysis

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

phosphoglycerate kinase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 408408Phosphoglycerate kinase HAMAP MF_00145
PRO_1000009603

Regions

Nucleotide binding364 – 3674ATP By similarity
Region24 – 263Substrate binding By similarity
Region62 – 654Substrate binding By similarity

Sites

Binding site391Substrate By similarity
Binding site1211Substrate By similarity
Binding site1611Substrate By similarity
Binding site2111ATP By similarity
Binding site3071ATP; via carbonyl oxygen By similarity
Binding site3381ATP By similarity

Sequences

Sequence LengthMass (Da)Tools
A1R6H1 [UniParc].

Last modified February 6, 2007. Version 1.
Checksum: 26D7A0B88FE2701A

FASTA40842,688
        10         20         30         40         50         60 
MTSHTLNELI AEGVRGRYIL VRSDLNVPLD GSAVTDDGRI KASLPVLKKL SDAGARVLVT 

        70         80         90        100        110        120 
AHLGRPKGAP EDKYSLKPAA ARLAELADFK VQLANDTVGD SAKELAAGLQ DGEVLVLENV 

       130        140        150        160        170        180 
RFDARETSKD DAERGAFADE LVALTGTNGA YVDDAFGAVH RKHASVFDVA TRLPSYLGDL 

       190        200        210        220        230        240 
VHTEVEVLRK LTTDTQRPYV VVLGGSKVSD KLAVIDNLLG KADTILVGGG MLFTFLAAAG 

       250        260        270        280        290        300 
HKVAGSLLEE DQIPVVQDYL KRASDAGTSF VIPTDVVVAS RFAADAEHEV VKADAIEDST 

       310        320        330        340        350        360 
FGASGIGLDI GPESAAAFAA QIEGAKTVFW NGPMGVFEFE AFSSGTRAIA QALTDTVAFT 

       370        380        390        400 
VVGGGDSAAA VRTLGFEDSQ FGHISTGGGA SLEYLEGKEL PGLSVLDR

« Hide

References

[1]"Secrets of soil survival revealed by the genome sequence of Arthrobacter aurescens TC1."
Mongodin E.F., Shapir N., Daugherty S.C., DeBoy R.T., Emerson J.B., Shvartzbeyn A., Radune D., Vamathevan J., Riggs F., Grinberg V., Khouri H.M., Wackett L.P., Nelson K.E., Sadowsky M.J.
PLoS Genet. 2:2094-2106(2006) [PubMed: 17194220] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: TC1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000474 Genomic DNA. Translation: ABM08929.1.
RefSeqYP_947833.1. NC_008711.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGA1R6H1.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4638872.
GenomeReviewsGene locus AAur_2089 in contig CP000474_GR.
KEGGaau:AAur_2089.
PATRIC20979592. VBIArtAur67810_2121.
TIGRAAur_2089.

Phylogenomic databases

eggNOGCOG0126.
HOGENOMHBG453500.
OMAAKPMAAI.
ProtClustDBPRK00073.

Enzyme and pathway databases

BioCycAAUR290340:AAUR_2089-MONOMER.

Family and domain databases

HAMAPMF_00145. Phosphoglyc_kinase.
[Tree]
InterProIPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view]
Gene3DG3DSA:3.40.50.1270. Phosphoglycerate_kinase_C. 1 hit.
G3DSA:3.40.50.1260. Phosphoglycerate_kinase_N. 1 hit.
KOK00927.
PANTHERPTHR11406. PGK. 1 hit.
PfamPF00162. PGK. 1 hit.
[Graphical view]
PIRSFPIRSF000724. Pgk. 1 hit.
PRINTSPR00477. PHGLYCKINASE.
SUPFAMSSF53748. PGK. 1 hit.
PROSITEPS00111. PGLYCERATE_KINASE. False negative.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePGK_ARTAT
AccessionPrimary (citable) accession number: A1R6H1
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: February 6, 2007
Last modified: December 14, 2011
This is version 37 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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