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A1R5C7 (DER_ARTAT) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 44. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
GTPase Der
Alternative name(s):
GTP-binding protein EngA
Gene names
Name:der
Synonyms:engA
Ordered Locus Names:AAur_1676
OrganismArthrobacter aurescens (strain TC1) [Complete proteome] [HAMAP]
Taxonomic identifier290340 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Micrococcineae › Micrococcaceae › Arthrobacter

Protein attributes

Sequence length491 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

GTPase that plays an essential role in the late steps of ribosome biogenesis By similarity. HAMAP MF_00195

Subunit structure

Associates with the 50S ribosomal subunit By similarity.

Sequence similarities

Belongs to the Era/MnmE GTP-binding protein family. Der subfamily.

Contains 2 G (guanine nucleotide-binding) domains.

Contains 1 KH-like domain.

Ontologies

Keywords
   Biological processRibosome biogenesis
   DomainRepeat
   LigandGTP-binding
Nucleotide-binding
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processribosome biogenesis

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentintracellular

Inferred from electronic annotation. Source: InterPro

   Molecular functionGTP binding

Inferred from electronic annotation. Source: UniProtKB-KW

nucleoside-triphosphatase activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 491491GTPase Der HAMAP MF_00195
PRO_1000124338

Regions

Domain65 – 170106G 1
Domain240 – 348109G 2
Domain402 – 48584KH-like
Nucleotide binding60 – 678GTP 1 Potential
Nucleotide binding107 – 1115GTP 1 Potential
Nucleotide binding169 – 1724GTP 1 Potential
Nucleotide binding235 – 2428GTP 2 Potential
Nucleotide binding282 – 2865GTP 2 Potential
Nucleotide binding347 – 3504GTP 2 Potential

Sequences

Sequence LengthMass (Da)Tools
A1R5C7 [UniParc].

Last modified February 6, 2007. Version 1.
Checksum: C78D09A407BC6304

FASTA49154,396
        10         20         30         40         50         60 
MAENLAALDD DEAELRAATL RAGLDDYDLD EEDAALLSGE YGDEGDEGPL KLDPVLAIIG 

        70         80         90        100        110        120 
RPNVGKSTLV NRILGRREAV VEDTPGVTRD RVMYSARWNG RNFTLVDTGG WEHDAKGIHA 

       130        140        150        160        170        180 
RVAEQAEMAV ELADAVLFVV DSAVGATATD EGVMKMLRKS KKPVIMVANK VDDFAQEADS 

       190        200        210        220        230        240 
ATLWGLGFGE PYPVSALHGR GVADLLDHVM DTLPEYSLVD GVERSGGPRR IALIGRPNVG 

       250        260        270        280        290        300 
KSSLLNKLAG SERVVVDPLA GTTRDPVDEF IELGDRTWRF VDTAGIRRRQ HMAQGADFYA 

       310        320        330        340        350        360 
SLRTQAALEK AEVAVVLLAV DEVLSEQDVR ILQLAIESGR ALVLAFNKWD LLDDERRRYL 

       370        380        390        400        410        420 
EREIEQDLAH VEWAPRVNIS AKTGWHKDRL VPALDIALES WDRRIPTGRL NAFLGELVAA 

       430        440        450        460        470        480 
HPHPVRGGKQ PRILFGTQAS SRPPKFVLFT TGFLDPGYRR FITRRLRETF GFEGTPIEVN 

       490 
MRVREKRGKK R

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References

[1]"Secrets of soil survival revealed by the genome sequence of Arthrobacter aurescens TC1."
Mongodin E.F., Shapir N., Daugherty S.C., DeBoy R.T., Emerson J.B., Shvartzbeyn A., Radune D., Vamathevan J., Riggs F., Grinberg V., Khouri H.M., Wackett L.P., Nelson K.E., Sadowsky M.J.
PLoS Genet. 2:2094-2106(2006) [PubMed: 17194220] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: TC1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000474 Genomic DNA. Translation: ABM09891.1.
RefSeqYP_947439.1. NC_008711.1.

3D structure databases

ProteinModelPortalA1R5C7.
ModBaseSearch...

Protein-protein interaction databases

STRINGA1R5C7.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4640519.
GenomeReviewsGene locus AAur_1676 in contig CP000474_GR.
KEGGaau:AAur_1676.
PATRIC20978746. VBIArtAur67810_1707.
TIGRAAur_1676.

Phylogenomic databases

eggNOGCOG1160.
HOGENOMHBG592135.
OMAQGADFYA.
ProtClustDBPRK03003.

Enzyme and pathway databases

BioCycAAUR290340:AAUR_1676-MONOMER.

Family and domain databases

HAMAPMF_00195. GTPase_Der.
[Tree]
InterProIPR003593. ATPase_AAA+_core.
IPR016484. GTP-bd_EngA.
IPR006073. GTP_binding_domain.
IPR015946. KH_dom-like_a/b.
IPR005225. Small_GTP-bd_dom.
[Graphical view]
Gene3DG3DSA:3.30.300.20. KH_prok. 1 hit.
KOK03977.
PANTHERPTHR11649:SF5. PTHR11649:SF5. 1 hit.
PfamPF01926. MMR_HSR1. 2 hits.
[Graphical view]
PIRSFPIRSF006485. GTP-binding_EngA. 1 hit.
PRINTSPR00326. GTP1OBG.
SMARTSM00382. AAA. 2 hits.
[Graphical view]
TIGRFAMsTIGR03594. GTPase_EngA. 1 hit.
TIGR00231. Small_GTP. 2 hits.
ProtoNetSearch...

Entry information

Entry nameDER_ARTAT
AccessionPrimary (citable) accession number: A1R5C7
Entry history
Integrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: February 6, 2007
Last modified: January 25, 2012
This is version 44 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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