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A1R592 (A1R592_ARTAT) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 39. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Argininosuccinate lyase HAMAP MF_00006
Short name=ASAL HAMAP MF_00006
EC=4.3.2.1 HAMAP MF_00006
Alternative name(s):
Arginosuccinase HAMAP MF_00006
Gene names
Name:argH HAMAP MF_00006
Ordered Locus Names:AAur_1638
OrganismArthrobacter aurescens (strain TC1) [Complete proteome] [HAMAP] EMBL ABM08637.1
Taxonomic identifier290340 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Micrococcineae › Micrococcaceae › Arthrobacter

Protein attributes

Sequence length491 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

2-(N(omega)-L-arginino)succinate = fumarate + L-arginine. HAMAP MF_00006

Pathway

Amino-acid biosynthesis; L-arginine biosynthesis; L-arginine from L-ornithine and carbamoyl phosphate: step 3/3. HAMAP MF_00006

Subcellular location

Cytoplasm By similarity HAMAP MF_00006.

Sequence similarities

Belongs to the lyase 1 family. Argininosuccinate lyase subfamily. HAMAP MF_00006

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Arginine biosynthesis HAMAP MF_00006
   Cellular componentCytoplasm HAMAP MF_00006
   Molecular functionLyase HAMAP MF_00006 EMBL ABM08637.1
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processarginine biosynthetic process via ornithine

Inferred from electronic annotation. Source: InterPro

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionargininosuccinate lyase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequences

Sequence LengthMass (Da)Tools
A1R592 [UniParc].

Last modified February 6, 2007. Version 1.
Checksum: 0FEAA92EF2196FFC

FASTA49152,302
        10         20         30         40         50         60 
MTPQQGPGTQ GSPAERSEVG ERSGTNEGAL WGGRFAGGPA DALAALSKST HFDWRLARYD 

        70         80         90        100        110        120 
IAGSKAHARV LAKAGLLDDA ELEGMLAALT QLDGDVASGA YLPAESDEDV HGSLERGLIE 

       130        140        150        160        170        180 
RAGTQLGGKL RAGRSRNDQV ATLGRMFLRD HARIIARGVL ATIDALVEQA KAHHGVAMPG 

       190        200        210        220        230        240 
RTHLQHAQPV LLSHHLLAHA WALLRDVQRL QDWDKRAGVS PYGSGALAGS SLGLDPEAVA 

       250        260        270        280        290        300 
ADLGFFSAVH NSIDGTASRD VFAEFAWVCS MIGVDLSRIS EEVIFWATKE FSFVTLHDSY 

       310        320        330        340        350        360 
STGSSIMPQK KNPDVAELAR GKAGRLIGNL TGLLATLKGL PLAYNRDLQE DKEPVFDAAD 

       370        380        390        400        410        420 
TLELLLPAVS GMIATLKFNT ERMEALAPQG FALATDIAEW LVRQGVPFRE AHELSGAAVK 

       430        440        450        460        470        480 
QAEGRGVELW DLTDEEYAAI SEHLTPQVRS VLSTEGSLNS RNSQGGTAPA AVERQLAALE 

       490 
AELDAARSYA S

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References

[1]"Secrets of soil survival revealed by the genome sequence of Arthrobacter aurescens TC1."
Mongodin E.F., Shapir N., Daugherty S.C., DeBoy R.T., Emerson J.B., Shvartzbeyn A., Radune D., Vamathevan J., Riggs F., Grinberg V., Khouri H.M., Wackett L.P., Nelson K.E., Sadowsky M.J.
PLoS Genet. 2:2094-2106(2006) [PubMed: 17194220] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000474 Genomic DNA. Translation: ABM08637.1.
RefSeqYP_947404.1. NC_008711.1.

3D structure databases

ProteinModelPortalA1R592.
ModBaseSearch...

Protein-protein interaction databases

STRINGA1R592.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4641031.
GenomeReviewsGene locus AAur_1638 in contig CP000474_GR.
KEGGaau:AAur_1638.
PATRIC20978670. VBIArtAur67810_1672.
TIGRAAur_1638.

Phylogenomic databases

eggNOGCOG0165.
HOGENOMHBG539632.
OMAMPGRTHL.
ProtClustDBPRK00855.

Family and domain databases

HAMAPMF_00006. Arg_succ_lyase.
[Tree]
InterProIPR009049. Argininosuccinate_lyase.
IPR003031. D_crystallin.
IPR000362. Fumarate_lyase.
IPR020557. Fumarate_lyase_CS.
IPR008948. L-Aspartase-like.
IPR022761. Lyase1_N.
[Graphical view]
KOK01755.
PANTHERPTHR11444:SF3. argH. 1 hit.
PfamPF00206. Lyase_1. 1 hit.
[Graphical view]
PRINTSPR00145. ARGSUCLYASE.
PR00149. FUMRATELYASE.
SUPFAMSSF48557. L-Aspartase-like. 1 hit.
TIGRFAMsTIGR00838. ArgH. 1 hit.
PROSITEPS00163. FUMARATE_LYASES. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA1R592_ARTAT
AccessionPrimary (citable) accession number: A1R592
Entry history
Integrated into UniProtKB/TrEMBL: February 6, 2007
Last sequence update: February 6, 2007
Last modified: December 14, 2011
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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