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Protein

Glutamyl-tRNA(Gln) amidotransferase subunit A

Gene

gatA

Organism
Paenarthrobacter aurescens (strain TC1)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).UniRule annotation

Catalytic activityi

ATP + L-glutamyl-tRNA(Gln) + L-glutamine = ADP + phosphate + L-glutaminyl-tRNA(Gln) + L-glutamate.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei88Charge relay systemUniRule annotation1
Active sitei163Charge relay systemUniRule annotation1
Active sitei187Acyl-ester intermediateUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLigase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamyl-tRNA(Gln) amidotransferase subunit AUniRule annotation (EC:6.3.5.7UniRule annotation)
Short name:
Glu-ADT subunit AUniRule annotation
Gene namesi
Name:gatAUniRule annotation
Ordered Locus Names:AAur_1449
OrganismiPaenarthrobacter aurescens (strain TC1)
Taxonomic identifieri290340 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaMicrococcalesMicrococcaceaePaenarthrobacter
Proteomesi
  • UP000000637 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000761191 – 522Glutamyl-tRNA(Gln) amidotransferase subunit AAdd BLAST522

Proteomic databases

PRIDEiA1R4R1.

Interactioni

Subunit structurei

Heterotrimer of A, B and C subunits.UniRule annotation

Protein-protein interaction databases

STRINGi290340.AAur_1449.

Structurei

3D structure databases

ProteinModelPortaliA1R4R1.
SMRiA1R4R1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the amidase family. GatA subfamily.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C3P. Bacteria.
COG0154. LUCA.
HOGENOMiHOG000116699.
KOiK02433.
OMAiPITQNVE.
OrthoDBiPOG091H00O9.

Family and domain databases

Gene3Di3.90.1300.10. 1 hit.
HAMAPiMF_00120. GatA. 1 hit.
InterProiView protein in InterPro
IPR000120. Amidase.
IPR020556. Amidase_CS.
IPR023631. Amidase_dom.
IPR004412. GatA.
PANTHERiPTHR11895. PTHR11895. 1 hit.
PTHR11895:SF104. PTHR11895:SF104. 1 hit.
PfamiView protein in Pfam
PF01425. Amidase. 1 hit.
SUPFAMiSSF75304. SSF75304. 1 hit.
TIGRFAMsiTIGR00132. gatA. 1 hit.
PROSITEiView protein in PROSITE
PS00571. AMIDASES. 1 hit.

Sequencei

Sequence statusi: Complete.

A1R4R1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTELKNELIR HSAADLAAKL ASREVTAVEV TQAHLDRIAD VDGQVNAFLH
60 70 80 90 100
VNSEEALAVA AEVDAARAAG GSAAEELHAL AGVPIAVKDL IVTIGQPTTA
110 120 130 140 150
GSKILEGWHS PYDATVVKKL RAAKMPILGK TNLDEFAMGS STEHSAYGPT
160 170 180 190 200
RNPWDLDRIP GGSGGGSAAA VAAFEAPLAL GTDTGGSIRQ PGAVTGTVGV
210 220 230 240 250
KPTYGAVSRY GAIAMASSLD QIGPVSRTVL DSALLQEVIG GHDPFDSTSL
260 270 280 290 300
TDPFNDLVAA ARVGNVAGMK IGIVKELHGE GYQAGVENRF NESLQLLKDA
310 320 330 340 350
GAEIVEVSCP NLKYALGAYY LIMPSEVSSN LAKFDGVRFG MRVLPKDGPM
360 370 380 390 400
TIERVMGATR AAGFGDEVKR RIILGTYALS AGYYDAYYGS AQKVRTLIQR
410 420 430 440 450
DFDAAFAKAD VLISPTAPTT AFKLGEKLDD PLAMYLNDVA TIPANLAGIP
460 470 480 490 500
GLSLPGGLAD EDGLPVGIQL LAPARQDARL YRVGAVLESI LEEKWGGPIL
510 520
AQAPDLKTAV LGAVSTTAGG SN
Length:522
Mass (Da):54,273
Last modified:February 6, 2007 - v1
Checksum:i8BD10C1B72A1014E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000474 Genomic DNA. Translation: ABM09114.1.
RefSeqiWP_011774170.1. NC_008711.1.

Genome annotation databases

EnsemblBacteriaiABM09114; ABM09114; AAur_1449.
GeneIDi29626197.
KEGGiaau:AAur_1449.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiGATA_PAEAT
AccessioniPrimary (citable) accession number: A1R4R1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: February 6, 2007
Last modified: June 7, 2017
This is version 71 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families