A1R4H7 (A1R4H7_ARTAT) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Deoxyribose-phosphate aldolase HAMAP MF_00114
Short name=DERA HAMAP MF_00114
EC=4.1.2.4 HAMAP MF_00114

Alternative name(s):
2-deoxy-D-ribose 5-phosphate aldolase HAMAP MF_00114
Phosphodeoxyriboaldolase HAMAP MF_00114

Gene names

Name:	deoC HAMAP MF_00114
Ordered Locus Names:	AAur_1359

Organism

Arthrobacter aurescens (strain TC1) [Complete proteome] [HAMAP] EMBL ABM07977.1

Taxonomic identifier

290340 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Micrococcineae › Micrococcaceae › Arthrobacter

Protein attributes

Sequence length	233 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate By similarity. HAMAP MF_00114 SAAS SAAS022979
Catalytic activity	2-deoxy-D-ribose 5-phosphate = D-glyceraldehyde 3-phosphate + acetaldehyde. HAMAP MF_00114 SAAS SAAS022979
Pathway	Carbohydrate degradation; 2-deoxy-D-ribose 1-phosphate degradation; D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-alpha-D-ribose 1-phosphate: step 2/2. HAMAP MF_00114 SAAS SAAS022979
Subcellular location	Cytoplasm By similarity HAMAP MF_00114 SAAS SAAS022979.
Sequence similarities	Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. HAMAP MF_00114

Ontologies

Keywords
Cellular component	Cytoplasm HAMAP MF_00114 SAAS SAAS022979
Ligand	Schiff base HAMAP MF_00114 SAAS SAAS022979
Molecular function	Lyase SAAS SAAS022979 HAMAP MF_00114 EMBL ABM07977.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	carbohydrate catabolic process Inferred from electronic annotation. Source: HAMAP deoxyribonucleotide catabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	deoxyribose-phosphate aldolase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	164	1	Schiff-base intermediate with acetaldehyde By similarity HAMAP MF_00114
	Active site	193	1	By similarity HAMAP MF_00114

Sequences

	Sequence		Length	Mass (Da)
	A1R4H7 [UniParc]. Last modified February 6, 2007. Version 1. Checksum: 48309AD0E82C95E8	FASTA	233	23,754
	10 20 30 40 50 60 MSNEAVAPAN IANIASYIDH TLLKPEASEA DVLKVCAEAI EYKFKSVCVN PVWVKTVTKA 70 80 90 100 110 120 LKGSGVLTCS VIGFPLGATP SDVKAFEARG AVLDGADEID MVINMASARA NDKGALVDDI 130 140 150 160 170 180 RAVSEPVHAG EAILKVIIET SMLTDEQKVI ACEAAVEAGA DFVKTSTGFN GGGATVEDVA 190 200 210 220 230 LMRKTVGPDL GVKASGGVRS LADAQAMIAA GATRIGASSG IAIVKGEQGS SAY

References

[1]

"Secrets of soil survival revealed by the genome sequence of Arthrobacter aurescens TC1." Mongodin E.F., Shapir N., Daugherty S.C., DeBoy R.T., Emerson J.B., Shvartzbeyn A., Radune D., Vamathevan J., Riggs F., Grinberg V., Khouri H.M., Wackett L.P., Nelson K.E., Sadowsky M.J. PLoS Genet. 2:2094-2106(2006) [PubMed: 17194220] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000474 Genomic DNA. Translation: ABM07977.1.
RefSeq	YP_947139.1. NC_008711.1.
3D structure databases
ProteinModelPortal	A1R4H7.
SMR	A1R4H7. Positions 8-228.
ModBase	Search...
Protein-protein interaction databases
STRING	A1R4H7.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4638556.
GenomeReviews	Gene locus AAur_1359 in contig CP000474_GR.
KEGG	aau:AAur_1359.
PATRIC	20978086. VBIArtAur67810_1383.
TIGR	AAur_1359.
Phylogenomic databases
eggNOG	COG0274.
HOGENOM	HBG636421.
OMA	IDHTNLK.
ProtClustDB	PRK00507.
Family and domain databases
HAMAP	MF_00114. DeoC_type1. [Tree]
InterPro	IPR013785. Aldolase_TIM. IPR011343. DeoC. IPR002915. DeoC/AroFGH_arch. IPR022979. Deoxyribose_phosphate_aldo_1. [Graphical view]
Gene3D	G3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
KO	K01619.
PANTHER	PTHR10889. DeoC. 1 hit.
Pfam	PF01791. DeoC. 1 hit. [Graphical view]
PIRSF	PIRSF001357. DeoC. 1 hit.
TIGRFAMs	TIGR00126. DeoC. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A1R4H7_ARTAT

Accession

Primary (citable) accession number: A1R4H7

Entry history

Integrated into UniProtKB/TrEMBL:	February 6, 2007
Last sequence update:	February 6, 2007
Last modified:	December 14, 2011
This is version 43 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)