A1R3G6 (A1R3G6_ARTAT) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Aminomethyltransferase 1 HAMAP MF_00259
EC=2.1.2.10 HAMAP MF_00259

Alternative name(s):
Glycine cleavage system T protein 1 HAMAP MF_00259

Gene names

Name:	gcvT EMBL ABM07023.1
Synonyms:	gcvT1 HAMAP MF_00259
Ordered Locus Names:	AAur_0988

Organism

Arthrobacter aurescens (strain TC1) [Complete proteome] [HAMAP] EMBL ABM07023.1

Taxonomic identifier

290340 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Micrococcineae › Micrococcaceae › Arthrobacter

Protein attributes

Sequence length	377 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	The glycine cleavage system catalyzes the degradation of glycine By similarity. HAMAP MF_00259
Catalytic activity	[Protein]-S(8)-aminomethyldihydrolipoyllysine + tetrahydrofolate = [protein]-dihydrolipoyllysine + 5,10-methylenetetrahydrofolate + NH3. HAMAP MF_00259
Subunit structure	The glycine cleavage system is composed of four proteins: P, T, L and H By similarity. HAMAP MF_00259
Sequence similarities	Belongs to the GcvT family. HAMAP MF_00259

Ontologies

Keywords
Molecular function	Aminotransferase HAMAP MF_00259 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycine decarboxylation via glycine cleavage system Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: InterPro
Molecular function	aminomethyltransferase activity Inferred from electronic annotation. Source: HAMAP transaminase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A1R3G6 [UniParc]. Last modified February 6, 2007. Version 1. Checksum: DE462AB1B815F615	FASTA	377	39,881
	10 20 30 40 50 60 MTENYTALYE EHKKLGASFT DFGGWQMPLK YSSELAEHHA VRKSAGLFDL SHMGEVWVTG 70 80 90 100 110 120 PEAAAFLDYA LVGKISAMAD GKAKYSLICQ EDGGIIDDLI TYRRGSEKFL VVPNAGNAKV 130 140 150 160 170 180 VATALLERAA GFDVEVQDAS AETSLIAVQG PLAEAILLRL VPVEQHALVT ELKYYAAVEV 190 200 210 220 230 240 PFTFDGGTQD LLLARTGYTG EDGFEIFVAN DSAAALWQAI AGAAEEGELT PAGLASRDSL 250 260 270 280 290 300 RLEAGMPLYG NELSREGNPF AAGLGPVVAL SKEGDFVGKD ALAALKADGA GSTSGRKLVG 310 320 330 340 350 360 LKGLGRRAGR GHYPVLKDGA VVGEVTSGQP SPTLGYPVAL AYVDVEHSEL GTALDIDLRG 370 KSEPFEVVAL PFYKRVR

References

[1]

"Secrets of soil survival revealed by the genome sequence of Arthrobacter aurescens TC1." Mongodin E.F., Shapir N., Daugherty S.C., DeBoy R.T., Emerson J.B., Shvartzbeyn A., Radune D., Vamathevan J., Riggs F., Grinberg V., Khouri H.M., Wackett L.P., Nelson K.E., Sadowsky M.J. PLoS Genet. 2:2094-2106(2006) [PubMed: 17194220] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000474 Genomic DNA. Translation: ABM07023.1.
RefSeq	YP_946778.1. NC_008711.1.
3D structure databases
ProteinModelPortal	A1R3G6.
ModBase	Search...
Protein-protein interaction databases
STRING	A1R3G6.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4638402.
GenomeReviews	Gene locus AAur_0988 in contig CP000474_GR.
KEGG	aau:AAur_0988.
PATRIC	20977320. VBIArtAur67810_1003.
TIGR	AAur_0988.
Phylogenomic databases
eggNOG	COG0404.
HOGENOM	HBG299834.
OMA	DAIANDC.
ProtClustDB	PRK00389.
Family and domain databases
HAMAP	MF_00259. GcvT. [Tree]
InterPro	IPR013977. GCV_T_C. IPR006222. GCV_T_N. IPR006223. GcvT. IPR022903. NH2_Me_Trfase. [Graphical view]
KO	K00605.
PANTHER	PTHR13847:SF5. PTHR13847:SF5. 1 hit.
Pfam	PF01571. GCV_T. 1 hit. PF08669. GCV_T_C. 1 hit. [Graphical view]
PIRSF	PIRSF006487. GcvT. 1 hit.
TIGRFAMs	TIGR00528. GcvT. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A1R3G6_ARTAT

Accession

Primary (citable) accession number: A1R3G6

Entry history

Integrated into UniProtKB/TrEMBL:	February 6, 2007
Last sequence update:	February 6, 2007
Last modified:	December 14, 2011
This is version 37 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)