ID   A1R0L5_BORT9            Unreviewed;       390 AA.
AC   A1R0L5;
DT   14-APR-2009, integrated into UniProtKB/TrEMBL.
DT   14-APR-2009, sequence version 1.
DT   27-MAR-2024, entry version 57.
DE   RecName: Full=thymidine kinase {ECO:0000256|ARBA:ARBA00012118};
DE            EC=2.7.1.21 {ECO:0000256|ARBA:ARBA00012118};
GN   OrderedLocusNames=BT0791 {ECO:0000313|EMBL:AAX18106.1};
OS   Borrelia turicatae (strain 91E135).
OC   Bacteria; Spirochaetota; Spirochaetia; Spirochaetales; Borreliaceae;
OC   Borrelia.
OX   NCBI_TaxID=314724 {ECO:0000313|EMBL:AAX18106.1, ECO:0000313|Proteomes:UP000001205};
RN   [1] {ECO:0000313|Proteomes:UP000001205}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=91E135 {ECO:0000313|Proteomes:UP000001205};
RA   Porcella S.F., Raffel S.J., Schrumpf M.E., Montgomery B., Smith T.,
RA   Schwan T.G.;
RT   "The genome sequence of Borrelia hermsii and Borrelia turicatae:
RT   comparative analysis of two agents of endemic N. America relapsing fever.";
RL   Submitted (DEC-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the thymidine kinase family.
CC       {ECO:0000256|ARBA:ARBA00007587}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP000049; AAX18106.1; -; Genomic_DNA.
DR   AlphaFoldDB; A1R0L5; -.
DR   KEGG; btu:BT0791; -.
DR   eggNOG; COG1435; Bacteria.
DR   HOGENOM; CLU_753704_0_0_12; -.
DR   Proteomes; UP000001205; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004797; F:thymidine kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0071897; P:DNA biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.60.20; -; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR001267; Thymidine_kinase.
DR   Pfam; PF00265; TK; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   DNA synthesis {ECO:0000256|ARBA:ARBA00022634};
KW   Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:AAX18106.1};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:AAX18106.1}.
SQ   SEQUENCE   390 AA;  45190 MW;  F5DF6EA7FC1C2B39 CRC64;
     MLFLLILLYL YKKSLTCLEF IFMSFYFNLV SGDTKSKLDD IVSISHFDFK ANLNLMLIIG
     PMGSGKTEYA AKIYKDSLII KNKSSKVLDP ITKGRRNRAN IFFIRNILDK KRFKDYPKNV
     IPYRGGGSDR IDGVDFAGDS FDVGQLIDDN PEYGTFIIDE TCFYDERLVF ILNKIALDSN
     VLFILPTLLY NFRKEIFNNT AKLLIEYSDK ICRLGAYCEH VNCMDESFLT YRYYFYKGEE
     IAAPYFDPLL IVGGDEIVES AIYPNYATRC SRHHYLVGRE YFFTILKPFA LLYTQGDRKL
     FEREIMDLSS NVRNSNFENS LLIESRGKCD IAVLENLLGL PFLAERALIT LSLECNILSK
     GDLKELIDKF SLSKDYIQKV IVSKEYQWIF
//