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A1R050 (ACKA_BORT9) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 24. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Acetate kinase
EC=2.7.2.1
Alternative name(s):
Acetokinase
Gene names
Name:ackA
Ordered Locus Names:BT0622
OrganismBorrelia turicatae (strain 91E135) [Complete proteome] [HAMAP]
Taxonomic identifier314724 [NCBI]
Taxonomic lineageBacteria › Spirochaetes › Spirochaetales › Spirochaetaceae › Borrelia

Protein attributes

Sequence length404 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + acetate = ADP + acetyl phosphate. HAMAP MF_00020

ATP + propanoate = ADP + propanoyl phosphate. HAMAP MF_00020

Pathway

Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2. HAMAP MF_00020

Subcellular location

Cytoplasm By similarity HAMAP MF_00020.

Sequence similarities

Belongs to the acetokinase family.

Ontologies

Keywords
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processorganic acid metabolic process

Inferred from electronic annotation. Source: InterPro

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

acetate kinase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 404404Acetate kinase HAMAP MF_00020
PRO_1000116793

Sequences

Sequence LengthMass (Da)Tools
A1R050 [UniParc].

Last modified April 14, 2009. Version 1.
Checksum: 8A7844578390BEA4

FASTA40445,453
        10         20         30         40         50         60 
MKILTINTGS SSLKFTLYKH KNTQILVSGT IEKIKTKKSI IKIKTKNGLL EKTDKHIKSH 

        70         80         90        100        110        120 
KEALKQLIRI LTNKKLKIIE NPDEIQGIGH RIVHGGPSFK NSTILNTNTL SELKKISKLA 

       130        140        150        160        170        180 
PLHNPIAIKV IEITLKIFPN AKQVLCFDTS WHKTMNENAF LYATPYSWYK DYNIRKYGFH 

       190        200        210        220        230        240 
GLSYSYITKR VATILNKPKE DLNLIILHLG NGSSINAVKK GLSYDTSMGL TPLEGLVMGT 

       250        260        270        280        290        300 
RSGDIDPAII PLMSKLLNKT PKKIEEILNK QSGMLGISLK SNDLRDIWEG VKNNEYNSKL 

       310        320        330        340        350        360 
AVEIMAYRIK KYIGSYLAVL DFNIDAIIFT AGIGVTDYGI RELSLKGFEK IGIEIDPQKN 

       370        380        390        400 
NLARDKHTES DISSEKSKTK ILVIPTNEEL TILEDTYNLI TKPS

« Hide

References

[1]"The genome sequence of Borrelia hermsii and Borrelia turicatae: comparative analysis of two agents of endemic N. America relapsing fever."
Porcella S.F., Raffel S.J., Schrumpf M.E., Montgomery B., Smith T., Schwan T.G.
Submitted (DEC-2004) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 91E135.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000049 Genomic DNA. Translation: AAX17942.1.
RefSeqYP_945612.1. NC_008710.1.

3D structure databases

ProteinModelPortalA1R050.
ModBaseSearch...

Protein-protein interaction databases

STRINGA1R050.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBBORT00000000780; EBBORP00000000780; EBBORG00000000780.
GeneID4642744.
GenomeReviewsGene locus BT0622 in contig CP000049_GR.
KEGGbtu:BT0622.
PATRIC20572963. VBIBorTur92789_0610.

Organism-specific databases

CMRSearch...

Phylogenomic databases

GeneTreeEBGT00050000007562.
OMAARNENSE.
ProtClustDBPRK00180.

Enzyme and pathway databases

BioCycBTUR314724:BT0622-MONOMER.

Family and domain databases

HAMAPMF_00020. Acetate_kinase.
[Tree]
InterProIPR004372. Ac/Proprionate_kinase.
IPR000890. Aliphatic_acid_kin_short-chain.
IPR023865. Aliphatic_acid_kinase_CS.
[Graphical view]
KOK00925.
PANTHERPTHR21060. Acetate_kin. 1 hit.
PfamPF00871. Acetate_kinase. 1 hit.
[Graphical view]
PIRSFPIRSF000722. Acetate_prop_kin. 1 hit.
PRINTSPR00471. ACETATEKNASE.
TIGRFAMsTIGR00016. AckA. 1 hit.
PROSITEPS01075. ACETATE_KINASE_1. 1 hit.
PS01076. ACETATE_KINASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameACKA_BORT9
AccessionPrimary (citable) accession number: A1R050
Entry history
Integrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: April 14, 2009
Last modified: January 25, 2012
This is version 24 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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