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Protein

Methionyl-tRNA formyltransferase

Gene

fmt

Organism
Borrelia turicatae (strain 91E135)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.UniRule annotation

Catalytic activityi

10-formyltetrahydrofolate + L-methionyl-tRNA(fMet) = tetrahydrofolate + N-formylmethionyl-tRNA(fMet).UniRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionTransferase
Biological processProtein biosynthesis

Enzyme and pathway databases

BioCyciBTUR314724:G1G4D-63-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Methionyl-tRNA formyltransferaseUniRule annotation (EC:2.1.2.9UniRule annotation)
Gene namesi
Name:fmtUniRule annotation
Ordered Locus Names:BT0064
OrganismiBorrelia turicatae (strain 91E135)
Taxonomic identifieri314724 [NCBI]
Taxonomic lineageiBacteriaSpirochaetesSpirochaetalesBorreliaceaeBorrelia
Proteomesi
  • UP000001205 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10001900091 – 309Methionyl-tRNA formyltransferaseAdd BLAST309

Interactioni

Protein-protein interaction databases

STRINGi314724.BT0064

Structurei

3D structure databases

ProteinModelPortaliA1QYL4
SMRiA1QYL4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni107 – 110Tetrahydrofolate (THF) bindingUniRule annotation4

Sequence similaritiesi

Belongs to the Fmt family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CAE Bacteria
COG0223 LUCA
HOGENOMiHOG000261177
KOiK00604
OMAiLRIVFMG
OrthoDBiPOG091H01YM

Family and domain databases

Gene3Di3.10.25.10, 1 hit
HAMAPiMF_00182 Formyl_trans, 1 hit
InterProiView protein in InterPro
IPR005794 Fmt
IPR005793 Formyl_trans_C
IPR037022 Formyl_trans_C_sf
IPR002376 Formyl_transf_N
IPR036477 Formyl_transf_N_sf
IPR011034 Formyl_transferase-like_C_sf
PfamiView protein in Pfam
PF02911 Formyl_trans_C, 1 hit
PF00551 Formyl_trans_N, 1 hit
SUPFAMiSSF50486 SSF50486, 1 hit
SSF53328 SSF53328, 1 hit
TIGRFAMsiTIGR00460 fmt, 1 hit

Sequencei

Sequence statusi: Complete.

A1QYL4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRIFFASSDS IALEVLRKVS DHYNVVGVLT APDKPSGRGL FLKVNDIKVE
60 70 80 90 100
AINRNITVLD PVVLNSDVIG MVKKLKPDLM LVFSYGKIFR QEFLDIFPMG
110 120 130 140 150
CINVHPSLLP KYRGPSPIQT AILNGDTIGG ITVQKMALEM DSGNILAQSQ
160 170 180 190 200
FEIKSFNTSA DIFRYVSLNS FNLVLEALSK LNKGHIGIVQ DSNQATYCSF
210 220 230 240 250
FNKQHRMLNF NLSAFEIKNK INACNPWPLA RAKLDKDEII FHRADFIKTT
260 270 280 290 300
DYSDQAIGKI VSFDPSKGIL VKTEDGILLL LELQRSGRKV VDYKSFYNGN

RDLIGKIFS
Length:309
Mass (Da):34,645
Last modified:April 14, 2009 - v1
Checksum:i1F33A459B02500E5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000049 Genomic DNA Translation: AAX17406.1
RefSeqiWP_011772025.1, NC_008710.1

Genome annotation databases

EnsemblBacteriaiAAX17406; AAX17406; BT0064
KEGGibtu:BT0064

Similar proteinsi

Entry informationi

Entry nameiFMT_BORT9
AccessioniPrimary (citable) accession number: A1QYL4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: April 14, 2009
Last modified: April 25, 2018
This is version 62 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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