Unreviewed, UniProtKB/TrEMBL A1L3Z2 (A1L3Z2_HUMAN)

Names and origin

Protein names

Submitted name:
    Activating transcription factor 2 EMBL AAI30336.1
Submitted name:
    Activating transcription factor 2, isoform CRA_c EMBL EAX11111.1

Gene names

Name:	ATF2 EMBL AAI30336.1
ORF Names:	hCG_15721 EMBL EAX11111.1

Organism

Homo sapiens (Human) EMBL AAI30336.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	505 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Sequence similarities

Belongs to the bZIP family. RuleBase RU000470V2 Contains 1 bZIP domain. Spearmint SPM004827

Ontologies

Keywords
Cellular component	Nucleus RuleBase RU000470V2 Spearmint SPM004827
Ligand	DNA-binding RuleBase RU000470V2 Spearmint SPM004827
Gene Ontology (GO)
Biological process	regulation of transcription, DNA-dependent Inferred from electronic annotation. Source: InterPro
Cellular component	nucleus Inferred from electronic annotation. Source: InterPro
Molecular function	protein dimerization activity Inferred from electronic annotation. Source: InterPro sequence-specific DNA binding Inferred from electronic annotation. Source: InterPro transcription factor activity Inferred from electronic annotation. Source: InterPro zinc ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A1L3Z2-1 [UniParc]. Last modified February 20, 2007. Version 1. Checksum: 0190EEFAEC8891A7	FASTA	505	54,537
	10 20 30 40 50 60 MKFKLHVNSA RQYKDLWNMS DDKPFLCTAP GCGQRFTNED HLAVHKHKHE MTLKFGPARN 70 80 90 100 110 120 DSVIVADQTP TPTRFLKNCE EVGLFNELAS PFENEFKKAS EDDIKKMPLD LSPLATPIIR 130 140 150 160 170 180 SKIEEPSVVE TTHQDSPLPH PESTTSDEKE VPLAQTAQPT SAIVRPASLQ VPNVLLTSSD 190 200 210 220 230 240 SSVIIQQAVP SPTSSTVITQ APSSNRPIVP VPGPFPLLLH LPNGQTMPVA IPASITSSNV 250 260 270 280 290 300 HVPAAVPLVR PVTMVPSVPG IPGPSSPQPV QSEAKMRLKA ALTQQHPPVT NGDTVKGHGS 310 320 330 340 350 360 GLVRTQSEES RPQSLQQPAT STTETPASPA HTTPQTQSTS GRRRRAANED PDEKRRKFLE 370 380 390 400 410 420 RNRAAASRCR QKRKVWVQSL EKKAEDLSSL NGQLQSEVTL LRNEVAQLKQ LLLAHKDCPV 430 440 450 460 470 480 TAMQKKSGYH TADKDDSSED ISVPSSPHTE AIQHSSVSTS NGVSSTSKAE AVATSVLTQM 490 500 ADQSTEPALS QIVMAPSSQS QPSGS

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Brain EMBL AAI30336.1.
[2]	Mural R.J., Istrail S., Sutton G., Florea L., Halpern A.L., Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S., Turner R. , Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W., Venter J.C. Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBLGenBankDDBJ	BC130335 mRNA. Translation: AAI30336.1. BC130337 mRNA. Translation: AAI30338.1. CH471058 Genomic DNA. Translation: EAX11111.1.
IPI	IPI00234446.
RefSeq	NP_001871.2.
UniGene	Hs.592510
3D structure databases
SMR	A1L3Z2. Positions 354-414.
ModBase	Search...
Proteomic databases
PRIDE	A1L3Z2.
Genome annotation databases
Ensembl	ENSG00000115966. Homo sapiens. [Contig view]
GeneID	1386.
KEGG	hsa:1386.
Organism-specific databases
HGNC	HGNC:784. ATF2.
GenAtlas	Search...
Phylogenomic databases
HOVERGEN	A1L3Z2.
OMA	A1L3Z2. QNEVTLL.
Gene expression databases
Bgee	A1L3Z2.
Family and domain databases
InterPro	IPR011616. bZIP_1. IPR004827. TF_bZIP. IPR016378. TF_cAMP-dep. IPR007087. Znf_C2H2. IPR015880. Znf_C2H2-like. [Graphical view]
Pfam	PF00170. bZIP_1. 1 hit. PF00096. zf-C2H2. 1 hit. [Graphical view]
PIRSF	PIRSF003153. ATF2_CRE-BP1. 1 hit.
SMART	SM00338. BRLZ. 1 hit. SM00355. ZnF_C2H2. 1 hit. [Graphical view]
PROSITE	PS50217. BZIP. 1 hit. PS00036. BZIP_BASIC. 1 hit. PS00028. ZINC_FINGER_C2H2_1. 1 hit. PS50157. ZINC_FINGER_C2H2_2. 1 hit. [Graphical view]
ProtoNet	Search...
Other Resources
NextBio	5631.

Entry information

Entry name

A1L3Z2_HUMAN

Accession

Primary (citable) accession number: A1L3Z2

Entry history

Integrated into UniProtKB/TrEMBL:	February 20, 2007
Last sequence update:	February 20, 2007
Last modified:	June 16, 2009
This is version 23 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)