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A1L3X4

- MT1DP_HUMAN

UniProt

A1L3X4 - MT1DP_HUMAN

Protein

Putative metallothionein MT1DP

Gene

MT1DP

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 2 out of 5- Protein uncertaini
  1. Functioni

    Metallothioneins have a high content of cysteine residues that bind various heavy metals.By similarity

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Metal bindingi5 – 51Divalent metal cation; cluster BBy similarity
    Metal bindingi7 – 71Divalent metal cation; cluster BBy similarity
    Metal bindingi13 – 131Divalent metal cation; cluster BBy similarity
    Metal bindingi15 – 151Divalent metal cation; cluster BBy similarity
    Metal bindingi19 – 191Divalent metal cation; cluster BBy similarity
    Metal bindingi21 – 211Divalent metal cation; cluster BBy similarity
    Metal bindingi26 – 261Divalent metal cation; cluster BBy similarity
    Metal bindingi29 – 291Divalent metal cation; cluster BBy similarity
    Metal bindingi33 – 331Divalent metal cation; cluster ABy similarity
    Metal bindingi34 – 341Divalent metal cation; cluster ABy similarity
    Metal bindingi36 – 361Divalent metal cation; cluster ABy similarity
    Metal bindingi37 – 371Divalent metal cation; cluster ABy similarity
    Metal bindingi41 – 411Divalent metal cation; cluster ABy similarity
    Metal bindingi44 – 441Divalent metal cation; cluster ABy similarity
    Metal bindingi48 – 481Divalent metal cation; cluster ABy similarity

    GO - Molecular functioni

    1. metal ion binding Source: UniProtKB-KW

    Keywords - Ligandi

    Metal-binding, Metal-thiolate cluster

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Putative metallothionein MT1DP
    Gene namesi
    Name:MT1DP
    Synonyms:MTM
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Unplaced

    Organism-specific databases

    HGNCiHGNC:7396. MT1DP.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 4949Putative metallothionein MT1DPPRO_0000343426Add
    BLAST

    Proteomic databases

    PaxDbiA1L3X4.
    PRIDEiA1L3X4.

    Expressioni

    Gene expression databases

    GenevestigatoriA1L3X4.

    Structurei

    3D structure databases

    ProteinModelPortaliA1L3X4.
    SMRiA1L3X4. Positions 1-30.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni1 – 2929BetaAdd
    BLAST
    Regioni30 – 4920AlphaAdd
    BLAST

    Sequence similaritiesi

    Phylogenomic databases

    InParanoidiA1L3X4.

    Family and domain databases

    Gene3Di4.10.10.10. 1 hit.
    InterProiIPR017854. Metalthion_dom.
    IPR023587. Metalthion_dom_vert.
    IPR003019. Metalthion_sfam_euk.
    IPR000006. Metalthion_vert.
    [Graphical view]
    PANTHERiPTHR23299. PTHR23299. 1 hit.
    PfamiPF00131. Metallothio. 1 hit.
    [Graphical view]
    PRINTSiPR00860. MTVERTEBRATE.
    SUPFAMiSSF57868. SSF57868. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    A1L3X4-1 [UniParc]FASTAAdd to Basket

    « Hide

    MDLSCSCATG GSCTCASSCK CKEYKCTSCK KNCCSCCPMG CAKCAQGCT    49
    Length:49
    Mass (Da):4,983
    Last modified:February 6, 2007 - v1
    Checksum:iD3FCBF95F9FBEFA1
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti45 – 451A → S in AAO32959. 1 PublicationCurated

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF348999 mRNA. Translation: AAO32959.2.
    UniGeneiHs.679600.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF348999 mRNA. Translation: AAO32959.2 .
    UniGenei Hs.679600.

    3D structure databases

    ProteinModelPortali A1L3X4.
    SMRi A1L3X4. Positions 1-30.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PaxDbi A1L3X4.
    PRIDEi A1L3X4.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Organism-specific databases

    GeneCardsi GC16P056677.
    HGNCi HGNC:7396. MT1DP.
    neXtProti NX_A1L3X4.
    GenAtlasi Search...

    Phylogenomic databases

    InParanoidi A1L3X4.

    Gene expression databases

    Genevestigatori A1L3X4.

    Family and domain databases

    Gene3Di 4.10.10.10. 1 hit.
    InterProi IPR017854. Metalthion_dom.
    IPR023587. Metalthion_dom_vert.
    IPR003019. Metalthion_sfam_euk.
    IPR000006. Metalthion_vert.
    [Graphical view ]
    PANTHERi PTHR23299. PTHR23299. 1 hit.
    Pfami PF00131. Metallothio. 1 hit.
    [Graphical view ]
    PRINTSi PR00860. MTVERTEBRATE.
    SUPFAMi SSF57868. SSF57868. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Yu L.
      Submitted (OCT-2004) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [MRNA].

    Entry informationi

    Entry nameiMT1DP_HUMAN
    AccessioniPrimary (citable) accession number: A1L3X4
    Secondary accession number(s): Q86YX1
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: July 1, 2008
    Last sequence update: February 6, 2007
    Last modified: October 1, 2014
    This is version 48 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Caution

    Could be the product of a pseudogene.Curated

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Human chromosome 16
      Human chromosome 16: entries, gene names and cross-references to MIM
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3