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A1L3X4 (MT1DP_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Last modified January 22, 2014. Version 47. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Putative metallothionein MT1DP
Gene names
Name:MT1DP
Synonyms:MTM
OrganismHomo sapiens (Human) [Reference proteome]
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length49 AA.
Sequence statusComplete.
Protein existenceUncertain

General annotation (Comments)

Function

Metallothioneins have a high content of cysteine residues that bind various heavy metals By similarity.

Sequence similarities

Belongs to the metallothionein superfamily. Type 1 family.

Caution

Could be the product of a pseudogene.

Ontologies

Keywords
   LigandMetal-binding
Metal-thiolate cluster
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Molecular_functionmetal ion binding

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 4949Putative metallothionein MT1DP
PRO_0000343426

Regions

Region1 – 2929Beta
Region30 – 4920Alpha

Sites

Metal binding51Divalent metal cation; cluster B By similarity
Metal binding71Divalent metal cation; cluster B By similarity
Metal binding131Divalent metal cation; cluster B By similarity
Metal binding151Divalent metal cation; cluster B By similarity
Metal binding191Divalent metal cation; cluster B By similarity
Metal binding211Divalent metal cation; cluster B By similarity
Metal binding261Divalent metal cation; cluster B By similarity
Metal binding291Divalent metal cation; cluster B By similarity
Metal binding331Divalent metal cation; cluster A By similarity
Metal binding341Divalent metal cation; cluster A By similarity
Metal binding361Divalent metal cation; cluster A By similarity
Metal binding371Divalent metal cation; cluster A By similarity
Metal binding411Divalent metal cation; cluster A By similarity
Metal binding441Divalent metal cation; cluster A By similarity
Metal binding481Divalent metal cation; cluster A By similarity

Experimental info

Sequence conflict451A → S in AAO32959. Ref.1

Sequences

Sequence LengthMass (Da)Tools
A1L3X4 [UniParc].

Last modified February 6, 2007. Version 1.
Checksum: D3FCBF95F9FBEFA1

FASTA494,983
        10         20         30         40 
MDLSCSCATG GSCTCASSCK CKEYKCTSCK KNCCSCCPMG CAKCAQGCT 

« Hide

References

[1]Yu L.
Submitted (OCT-2004) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [MRNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AF348999 mRNA. Translation: AAO32959.2.
UniGeneHs.679600.

3D structure databases

ProteinModelPortalA1L3X4.
SMRA1L3X4. Positions 1-30.
ModBaseSearch...
MobiDBSearch...

Proteomic databases

PaxDbA1L3X4.
PRIDEA1L3X4.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Organism-specific databases

GeneCardsGC16P056677.
HGNCHGNC:7396. MT1DP.
neXtProtNX_A1L3X4.
GenAtlasSearch...

Phylogenomic databases

InParanoidA1L3X4.

Gene expression databases

GenevestigatorA1L3X4.

Family and domain databases

Gene3D4.10.10.10. 1 hit.
InterProIPR017854. Metalthion_dom.
IPR023587. Metalthion_dom_vert.
IPR003019. Metalthion_sfam_euk.
IPR000006. Metalthion_vert.
[Graphical view]
PANTHERPTHR23299. PTHR23299. 1 hit.
PfamPF00131. Metallothio. 1 hit.
[Graphical view]
PRINTSPR00860. MTVERTEBRATE.
SUPFAMSSF57868. SSF57868. 1 hit.
ProtoNetSearch...

Entry information

Entry nameMT1DP_HUMAN
AccessionPrimary (citable) accession number: A1L3X4
Secondary accession number(s): Q86YX1
Entry history
Integrated into UniProtKB/Swiss-Prot: July 1, 2008
Last sequence update: February 6, 2007
Last modified: January 22, 2014
This is version 47 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Relevant documents

SIMILARITY comments

Index of protein domains and families

Human chromosome 16

Human chromosome 16: entries, gene names and cross-references to MIM