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A1L3X4

- MT1DP_HUMAN

UniProt

A1L3X4 - MT1DP_HUMAN

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Protein
Putative metallothionein MT1DP
Gene
MT1DP, MTM
Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 2 out of 5 - Protein uncertaini

Functioni

Metallothioneins have a high content of cysteine residues that bind various heavy metals By similarity.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi5 – 51Divalent metal cation; cluster B By similarity
Metal bindingi7 – 71Divalent metal cation; cluster B By similarity
Metal bindingi13 – 131Divalent metal cation; cluster B By similarity
Metal bindingi15 – 151Divalent metal cation; cluster B By similarity
Metal bindingi19 – 191Divalent metal cation; cluster B By similarity
Metal bindingi21 – 211Divalent metal cation; cluster B By similarity
Metal bindingi26 – 261Divalent metal cation; cluster B By similarity
Metal bindingi29 – 291Divalent metal cation; cluster B By similarity
Metal bindingi33 – 331Divalent metal cation; cluster A By similarity
Metal bindingi34 – 341Divalent metal cation; cluster A By similarity
Metal bindingi36 – 361Divalent metal cation; cluster A By similarity
Metal bindingi37 – 371Divalent metal cation; cluster A By similarity
Metal bindingi41 – 411Divalent metal cation; cluster A By similarity
Metal bindingi44 – 441Divalent metal cation; cluster A By similarity
Metal bindingi48 – 481Divalent metal cation; cluster A By similarity

GO - Molecular functioni

  1. metal ion binding Source: UniProtKB-KW
Complete GO annotation...

Keywords - Ligandi

Metal-binding, Metal-thiolate cluster

Names & Taxonomyi

Protein namesi
Recommended name:
Putative metallothionein MT1DP
Gene namesi
Name:MT1DP
Synonyms:MTM
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Unplaced

Organism-specific databases

HGNCiHGNC:7396. MT1DP.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 4949Putative metallothionein MT1DP
PRO_0000343426Add
BLAST

Proteomic databases

PaxDbiA1L3X4.
PRIDEiA1L3X4.

Expressioni

Gene expression databases

GenevestigatoriA1L3X4.

Structurei

3D structure databases

ProteinModelPortaliA1L3X4.
SMRiA1L3X4. Positions 1-30.

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni1 – 2929Beta
Add
BLAST
Regioni30 – 4920Alpha
Add
BLAST

Sequence similaritiesi

Phylogenomic databases

InParanoidiA1L3X4.

Family and domain databases

Gene3Di4.10.10.10. 1 hit.
InterProiIPR017854. Metalthion_dom.
IPR023587. Metalthion_dom_vert.
IPR003019. Metalthion_sfam_euk.
IPR000006. Metalthion_vert.
[Graphical view]
PANTHERiPTHR23299. PTHR23299. 1 hit.
PfamiPF00131. Metallothio. 1 hit.
[Graphical view]
PRINTSiPR00860. MTVERTEBRATE.
SUPFAMiSSF57868. SSF57868. 1 hit.

Sequencei

Sequence statusi: Complete.

A1L3X4-1 [UniParc]FASTAAdd to Basket

« Hide

MDLSCSCATG GSCTCASSCK CKEYKCTSCK KNCCSCCPMG CAKCAQGCT    49
Length:49
Mass (Da):4,983
Last modified:February 6, 2007 - v1
Checksum:iD3FCBF95F9FBEFA1
GO

Sequence conflict

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti45 – 451A → S in AAO32959. 1 Publication

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF348999 mRNA. Translation: AAO32959.2.
UniGeneiHs.679600.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF348999 mRNA. Translation: AAO32959.2 .
UniGenei Hs.679600.

3D structure databases

ProteinModelPortali A1L3X4.
SMRi A1L3X4. Positions 1-30.
ModBasei Search...

Proteomic databases

PaxDbi A1L3X4.
PRIDEi A1L3X4.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Organism-specific databases

GeneCardsi GC16P056677.
HGNCi HGNC:7396. MT1DP.
neXtProti NX_A1L3X4.
GenAtlasi Search...

Phylogenomic databases

InParanoidi A1L3X4.

Gene expression databases

Genevestigatori A1L3X4.

Family and domain databases

Gene3Di 4.10.10.10. 1 hit.
InterProi IPR017854. Metalthion_dom.
IPR023587. Metalthion_dom_vert.
IPR003019. Metalthion_sfam_euk.
IPR000006. Metalthion_vert.
[Graphical view ]
PANTHERi PTHR23299. PTHR23299. 1 hit.
Pfami PF00131. Metallothio. 1 hit.
[Graphical view ]
PRINTSi PR00860. MTVERTEBRATE.
SUPFAMi SSF57868. SSF57868. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Yu L.
    Submitted (OCT-2004) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].

Entry informationi

Entry nameiMT1DP_HUMAN
AccessioniPrimary (citable) accession number: A1L3X4
Secondary accession number(s): Q86YX1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 1, 2008
Last sequence update: February 6, 2007
Last modified: January 22, 2014
This is version 47 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

Could be the product of a pseudogene.

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 16
    Human chromosome 16: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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