A1L3X4 (MT1DP_HUMAN) Reviewed, UniProtKB/Swiss-Prot
Last modified
May 1, 2013.
Version 45.
History...
Clusters with 
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames and origin
| Protein names | Recommended name: Putative metallothionein MT1DP | ||||
| Gene names |
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| Organism | Homo sapiens (Human) [Reference proteome] | ||||
| Taxonomic identifier | 9606 [NCBI] | ||||
| Taxonomic lineage | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Protein attributes
| Sequence length | 49 AA. |
| Sequence status | Complete. |
| Protein existence | Uncertain |
General annotation (Comments)
| Function | Metallothioneins have a high content of cysteine residues that bind various heavy metals By similarity. |
| Sequence similarities | Belongs to the metallothionein superfamily. Type 1 family. |
| Caution | Could be the product of a pseudogene. |
Ontologies
| Keywords | |
|---|---|
| Ligand | Metal-binding Metal-thiolate cluster |
| Technical term | Complete proteome Reference proteome |
| Gene Ontology (GO) | |
| Molecular_function | metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Chain | 1 – 49 | 49 | Putative metallothionein MT1DP | PRO_0000343426 | |||||
Regions | |||||||||
| Region | 1 – 29 | 29 | Beta | ||||||
| Region | 30 – 49 | 20 | Alpha | ||||||
Sites | |||||||||
| Metal binding | 5 | 1 | Divalent metal cation; cluster B By similarity | ||||||
| Metal binding | 7 | 1 | Divalent metal cation; cluster B By similarity | ||||||
| Metal binding | 13 | 1 | Divalent metal cation; cluster B By similarity | ||||||
| Metal binding | 15 | 1 | Divalent metal cation; cluster B By similarity | ||||||
| Metal binding | 19 | 1 | Divalent metal cation; cluster B By similarity | ||||||
| Metal binding | 21 | 1 | Divalent metal cation; cluster B By similarity | ||||||
| Metal binding | 26 | 1 | Divalent metal cation; cluster B By similarity | ||||||
| Metal binding | 29 | 1 | Divalent metal cation; cluster B By similarity | ||||||
| Metal binding | 33 | 1 | Divalent metal cation; cluster A By similarity | ||||||
| Metal binding | 34 | 1 | Divalent metal cation; cluster A By similarity | ||||||
| Metal binding | 36 | 1 | Divalent metal cation; cluster A By similarity | ||||||
| Metal binding | 37 | 1 | Divalent metal cation; cluster A By similarity | ||||||
| Metal binding | 41 | 1 | Divalent metal cation; cluster A By similarity | ||||||
| Metal binding | 44 | 1 | Divalent metal cation; cluster A By similarity | ||||||
| Metal binding | 48 | 1 | Divalent metal cation; cluster A By similarity | ||||||
Experimental info | |||||||||
| Sequence conflict | 45 | 1 | A → S in AAO32959. Ref.1 | ||||||
Sequences
References
| [1] | Yu L. Submitted (OCT-2004) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [MRNA]. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | AF348999 mRNA. Translation: AAO32959.2. |
| IPI | IPI00329471. |
| UniGene | Hs.679600. |
3D structure databases | |
| ProteinModelPortal | A1L3X4. |
| SMR | A1L3X4. Positions 1-30. |
| ModBase | Search... |
Proteomic databases | |
| PaxDb | A1L3X4. |
| PRIDE | A1L3X4. |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Organism-specific databases | |
| GeneCards | GC16P056677. |
| HGNC | HGNC:7396. MT1DP. |
| neXtProt | NX_A1L3X4. |
| GenAtlas | Search... |
Phylogenomic databases | |
| InParanoid | A1L3X4. |
Gene expression databases | |
| Genevestigator | A1L3X4. |
Family and domain databases | |
| Gene3D | 4.10.10.10. 1 hit. |
| InterPro | IPR017854. Metalthion_dom. IPR023587. Metalthion_dom_vert. IPR003019. Metalthion_sfam_euk. IPR000006. Metalthion_vert. [Graphical view] |
| PANTHER | PTHR23299. PTHR23299. 1 hit. |
| Pfam | PF00131. Metallothio. 1 hit. [Graphical view] |
| PRINTS | PR00860. MTVERTEBRATE. |
| SUPFAM | SSF57868. Metallothionein_sfam. 1 hit. |
| ProtoNet | Search... |
Entry information
| Entry name | MT1DP_HUMAN | ||||||||
| Accession | Primary (citable) accession number: A1L3X4 Secondary accession number(s): Q86YX1 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation program | Chordata Protein Annotation Program | ||||||||
| Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. | ||||||||
Relevant documents
| Human chromosome 16 Human chromosome 16: entries, gene names and cross-references to MIM |
| SIMILARITY comments Index of protein domains and families |