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A1L3P4 (A1L3P4_MOUSE) Unreviewed, UniProtKB/TrEMBL

Last modified July 9, 2014. Version 65. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein attributes

Sequence length702 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

Ontologies

Keywords
   Biological processAntiport SAAS SAAS006153 RuleBase RU003722
Ion transport
Sodium transport RuleBase RU003722
Transport
   Cellular componentMembrane
   DomainTransmembrane RuleBase RU003721
   LigandSodium
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processaxon extension

Inferred from sequence orthology PubMed 24035762. Source: MGI

brain-derived neurotrophic factor receptor signaling pathway

Inferred from mutant phenotype PubMed 24035762. Source: MGI

dendrite extension

Inferred from sequence orthology PubMed 24035762. Source: MGI

dendritic spine development

Inferred from mutant phenotype PubMed 24035762. Source: MGI

neuron projection morphogenesis

Inferred from sequence orthology PubMed 24035762. Source: MGI

proton transport

Inferred from mutant phenotype PubMed 24035762. Source: MGI

regulation of neurotrophin TRK receptor signaling pathway

Inferred from mutant phenotype PubMed 24035762. Source: MGI

regulation of pH

Inferred from electronic annotation. Source: InterPro

synapse organization

Inferred from mutant phenotype PubMed 24035762. Source: MGI

   Cellular_componentaxon terminus

Inferred from direct assay PubMed 23303939. Source: MGI

axonal spine

Inferred from direct assay PubMed 23303939. Source: MGI

cytoplasmic vesicle

Inferred from direct assay PubMed 23303939. Source: MGI

dendrite

Inferred from direct assay PubMed 23303939. Source: MGI

early endosome

Inferred from direct assay PubMed 24035762. Source: MGI

early endosome membrane

Inferred from electronic annotation. Source: Ensembl

endoplasmic reticulum membrane

Inferred from electronic annotation. Source: Ensembl

endosome

Inferred from direct assay PubMed 24035762. Source: MGI

integral component of membrane

Inferred from electronic annotation. Source: UniProtKB-KW

late endosome

Inferred from direct assay PubMed 24035762. Source: MGI

mitochondrion

Inferred from direct assay PubMed 14651853. Source: MGI

plasma membrane

Inferred from direct assay PubMed 23303939. Source: MGI

recycling endosome

Inferred from direct assay PubMed 23303939PubMed 24035762. Source: MGI

recycling endosome membrane

Inferred from electronic annotation. Source: Ensembl

synapse

Inferred from direct assay PubMed 24035762. Source: MGI

   Molecular_functionsodium:proton antiporter activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequences

Sequence LengthMass (Da)Tools
A1L3P4 [UniParc].

Last modified February 6, 2007. Version 1.
Checksum: 243F0126533B5547

FASTA70277,953
        10         20         30         40         50         60 
MAGARRGWRL APVRRGVCGP RARPLMRPLW LLFAVSFFGW TGALDGSGGT TRAMDEEIVS 

        70         80         90        100        110        120 
EKQAEESHRQ DSANLLIFIL LLTLTILTIW LFKHRRARFL HETGLAMIYG LLVGLVLRYG 

       130        140        150        160        170        180 
IHVPSDVNNV TLSCEVQSSP TTLLVNVSGK FYEYTLKGEI SSHELNNVQD NEMLRKVTFD 

       190        200        210        220        230        240 
PEVFFNILLP PIIFYAGYSL KRRHFFRNLG SILAYAFLGT AISCFVIGSI MYGCVTLMKV 

       250        260        270        280        290        300 
TGQLAGDFYF TDCLLFGAIV SATDPVTVLA IFHELQVDVE LYALLFGESV LNDAVAIVLS 

       310        320        330        340        350        360 
SSIVAYQPAG DNSHTFDVTA MFKSIGIFLG IFSGSFAMGA ATGVVTALVT KFTKLREFQL 

       370        380        390        400        410        420 
LETGLFFLMS WSTFLLAEAW GFTGVVAVLF CGITQAHYTY NNLSTESQHR TKQLFELLNF 

       430        440        450        460        470        480 
LAENFIFSYM GLTLFTFQNH VFNPTFVVGA FIAIFLGRAA NIYPLSLLLN LGRRSKIGSN 

       490        500        510        520        530        540 
FQHMMMFAGL RGAMAFALAI RDTATYARQM MFSTTLLIVF FTVWVFGGGT TAMLSCLHIR 

       550        560        570        580        590        600 
VGVDSDQEHL GVPDNERRTT KAESAWLFRM WYNFDHNYLK PLLTHSGPPL TTTLPACCGP 

       610        620        630        640        650        660 
IARCLTSPQA YENQEQLKDD DSDLILNDGD ISLTYGDSTV NTESATASAP RRFMGNSSED 

       670        680        690        700 
ALDRELTFGD HELVIRGTRL VLPMDDSEPA LNSLDDTRHS PA 

« Hide

References

« Hide 'large scale' references
[1]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M. expand/collapse author list , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: PCR rescued clones EMBL AAI30222.1.
[2]"The phagosomal proteome in interferon-gamma-activated macrophages."
Trost M., English L., Lemieux S., Courcelles M., Desjardins M., Thibault P.
Immunity 30:143-154(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
[3]"Lineage-specific biology revealed by a finished genome assembly of the mouse."
Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S. expand/collapse author list , Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., Eichler E.E., Ponting C.P.
PLoS Biol. 7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: C57BL/6J Ensembl ENSMUSP00000076922.
[4]Ensembl
Submitted (FEB-2012) to UniProtKB
Cited for: IDENTIFICATION.
Strain: C57BL/6J Ensembl ENSMUSP00000076922.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AC048362 Genomic DNA. No translation available.
AL672085 Genomic DNA. No translation available.
BC130221 mRNA. Translation: AAI30222.1.
RefSeqNP_766368.2. NM_172780.3.
UniGeneMm.17815.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSMUST00000077741; ENSMUSP00000076922; ENSMUSG00000060681.
GeneID236794.
KEGGmmu:236794.
UCSCuc009tgk.2. mouse.

Organism-specific databases

CTD10479.
MGIMGI:2443511. Slc9a6.

Phylogenomic databases

eggNOGCOG0025.
GeneTreeENSGT00560000076802.
HOGENOMHOG000172307.
HOVERGENHBG055575.
InParanoidA1L3P4.
KOK12041.
OMADQEHLGV.
OrthoDBEOG7NW69D.
TreeFamTF318755.

Gene expression databases

GenevestigatorA1L3P4.

Family and domain databases

InterProIPR006153. Cation/H_exchanger.
IPR018422. Cation/H_exchanger_CPA1.
IPR002090. Na/H_exchanger_6.
IPR004709. NaH_exchanger.
[Graphical view]
PANTHERPTHR10110. PTHR10110. 1 hit.
PfamPF00999. Na_H_Exchanger. 1 hit.
[Graphical view]
PRINTSPR01084. NAHEXCHNGR.
PR01088. NAHEXCHNGR6.
TIGRFAMsTIGR00840. b_cpa1. 1 hit.
ProtoNetSearch...

Other

NextBio383086.
PROA1L3P4.
SOURCESearch...

Entry information

Entry nameA1L3P4_MOUSE
AccessionPrimary (citable) accession number: A1L3P4
Entry history
Integrated into UniProtKB/TrEMBL: February 6, 2007
Last sequence update: February 6, 2007
Last modified: July 9, 2014
This is version 65 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)