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Protein
Submitted name:

Myeloid zinc finger 1

Gene

Mzf1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processTranscription, Transcription regulationSAAS annotation
LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
Myeloid zinc finger 1Imported
Gene namesi
Name:Mzf1Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 7

Organism-specific databases

MGIiMGI:107457. Mzf1.

Subcellular locationi

  • Nucleus PROSITE-ProRule annotationSAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotationSAAS annotation

Expressioni

Gene expression databases

BgeeiENSMUSG00000030380.
ExpressionAtlasiA1L358. baseline and differential.

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000069122.

Structurei

3D structure databases

ProteinModelPortaliA1L358.
SMRiA1L358.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini45 – 127SCAN boxInterPro annotationAdd BLAST83
Domaini357 – 384C2H2-typeInterPro annotationAdd BLAST28
Domaini385 – 412C2H2-typeInterPro annotationAdd BLAST28
Domaini413 – 440C2H2-typeInterPro annotationAdd BLAST28
Domaini441 – 463C2H2-typeInterPro annotationAdd BLAST23
Domaini486 – 513C2H2-typeInterPro annotationAdd BLAST28
Domaini514 – 541C2H2-typeInterPro annotationAdd BLAST28
Domaini542 – 569C2H2-typeInterPro annotationAdd BLAST28
Domaini570 – 597C2H2-typeInterPro annotationAdd BLAST28
Domaini598 – 625C2H2-typeInterPro annotationAdd BLAST28
Domaini626 – 653C2H2-typeInterPro annotationAdd BLAST28
Domaini654 – 681C2H2-typeInterPro annotationAdd BLAST28
Domaini682 – 709C2H2-typeInterPro annotationAdd BLAST28
Domaini710 – 735C2H2-typeInterPro annotationAdd BLAST26

Keywords - Domaini

RepeatSAAS annotation, Zinc-fingerSAAS annotation

Phylogenomic databases

eggNOGiKOG1721. Eukaryota.
COG5048. LUCA.
GeneTreeiENSGT00730000111047.
HOGENOMiHOG000234619.
HOVERGENiHBG018163.
TreeFamiTF337913.

Family and domain databases

Gene3Di2.40.155.10. 4 hits.
3.30.160.60. 8 hits.
3.30.40.10. 2 hits.
InterProiView protein in InterPro
IPR023413. GFP-like.
IPR008916. Retrov_capsid_C.
IPR003309. SCAN_dom.
IPR013087. Znf_C2H2_type.
IPR013083. Znf_RING/FYVE/PHD.
PfamiView protein in Pfam
PF02023. SCAN. 1 hit.
SMARTiView protein in SMART
SM00431. SCAN. 1 hit.
SM00355. ZnF_C2H2. 13 hits.
SUPFAMiSSF47353. SSF47353. 1 hit.
SSF57667. SSF57667. 7 hits.
PROSITEiView protein in PROSITE
PS50804. SCAN_BOX. 1 hit.
PS00028. ZINC_FINGER_C2H2_1. 13 hits.
PS50157. ZINC_FINGER_C2H2_2. 13 hits.

Sequencei

Sequence statusi: Complete.

A1L358-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRPTVLGSSG CAPPENEPAL VKLEDSDSDD EREDILWDPG LEAARLRFRC
60 70 80 90 100
FRYEDAIGPQ EALAQLRELC HQWLRPEVHS KEQVLELLVL EQFLGALPPE
110 120 130 140 150
IQAQVQGQWP GSPEEAAALV DRLRWELDGP RKWVTVQVQG KEVLSEKMEP
160 170 180 190 200
SSFQPRPHIK LQTPDPGAET PQGAMQELPL NLPMKEETEL LGNPELLESG
210 220 230 240 250
PLPAAQEAAA TLLPKETQGH GTTLDQTSPH SDTEPDVPPW SEDPMPLWHE
260 270 280 290 300
EVGGIFSPGF TLQMDSITAE PDMMSPHLHV PWDLDMASLS GQIQSPTTEG
310 320 330 340 350
GFAHALVLPS DPGGEQDPAC EDPCPSVGPA LVATRWHAPR GRSQSHPRSG
360 370 380 390 400
TGAMRGGRCD VCGKVFSQRS NLLRHQKIHT GERPFVCGEC GRSFSRSSHL
410 420 430 440 450
LRHQLTHTEE RPFVCRDCGQ GFVRSARLEE HRRVHTGEQP FRCTECGQSF
460 470 480 490 500
RQRSNLLQHQ RIHGDPPGPA PSILPLAGVP EPPGPFPCSE CCESFPRRAV
510 520 530 540 550
LLEHQAVHTG DKSFGCVECG ERFGRRSVLL QHRRVHSGER PFACAECGQS
560 570 580 590 600
FRQRSNLTQH QRIHTGERPF ACAECGKTFR QRPTLTQHLR VHTGEKPFAC
610 620 630 640 650
PECGQRFSQR LKLTRHQRTH TGEKPYCCGE CGLGFTQVSR LTEHQRIHTG
660 670 680 690 700
ERPFACPECG QSFRQHANLT QHRRIHTGER PYACPECGKA FRQRPTLTQH
710 720 730
LRTHRHEKPF ACQDCGRRFN QSTKLIQHQR VHSTE
Length:735
Mass (Da):82,462
Last modified:February 6, 2007 - v1
Checksum:i23CF252EF3F4C0E2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC121301 Genomic DNA. No translation available.
BC129905 mRNA. Translation: AAI29906.1.
RefSeqiNP_665818.2. NM_145819.2.
UniGeneiMm.10103.

Genome annotation databases

EnsembliENSMUST00000182515; ENSMUSP00000138387; ENSMUSG00000030380.
GeneIDi109889.
UCSCiuc009fff.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC121301 Genomic DNA. No translation available.
BC129905 mRNA. Translation: AAI29906.1.
RefSeqiNP_665818.2. NM_145819.2.
UniGeneiMm.10103.

3D structure databases

ProteinModelPortaliA1L358.
SMRiA1L358.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000069122.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000182515; ENSMUSP00000138387; ENSMUSG00000030380.
GeneIDi109889.
UCSCiuc009fff.2. mouse.

Organism-specific databases

CTDi7593.
MGIiMGI:107457. Mzf1.

Phylogenomic databases

eggNOGiKOG1721. Eukaryota.
COG5048. LUCA.
GeneTreeiENSGT00730000111047.
HOGENOMiHOG000234619.
HOVERGENiHBG018163.
TreeFamiTF337913.

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000030380.
ExpressionAtlasiA1L358. baseline and differential.

Family and domain databases

Gene3Di2.40.155.10. 4 hits.
3.30.160.60. 8 hits.
3.30.40.10. 2 hits.
InterProiView protein in InterPro
IPR023413. GFP-like.
IPR008916. Retrov_capsid_C.
IPR003309. SCAN_dom.
IPR013087. Znf_C2H2_type.
IPR013083. Znf_RING/FYVE/PHD.
PfamiView protein in Pfam
PF02023. SCAN. 1 hit.
SMARTiView protein in SMART
SM00431. SCAN. 1 hit.
SM00355. ZnF_C2H2. 13 hits.
SUPFAMiSSF47353. SSF47353. 1 hit.
SSF57667. SSF57667. 7 hits.
PROSITEiView protein in PROSITE
PS50804. SCAN_BOX. 1 hit.
PS00028. ZINC_FINGER_C2H2_1. 13 hits.
PS50157. ZINC_FINGER_C2H2_2. 13 hits.
ProtoNetiSearch...

Entry informationi

Entry nameiA1L358_MOUSE
AccessioniPrimary (citable) accession number: A1L358
Entry historyiIntegrated into UniProtKB/TrEMBL: February 6, 2007
Last sequence update: February 6, 2007
Last modified: April 12, 2017
This is version 89 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.