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Protein
Submitted name:

Myeloid zinc finger 1

Gene

Mzf1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Transcription, Transcription regulationSAAS annotation

Keywords - Ligandi

Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
Myeloid zinc finger 1Imported
Submitted name:
Protein Mzf1Imported
Gene namesi
Name:Mzf1Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 7

Organism-specific databases

MGIiMGI:107457. Mzf1.

Subcellular locationi

  • Nucleus SAAS annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

NucleusSAAS annotation

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000069122.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini45 – 12783SCAN boxInterPro annotationAdd
BLAST
Domaini357 – 38428C2H2-typeInterPro annotationAdd
BLAST
Domaini385 – 41228C2H2-typeInterPro annotationAdd
BLAST
Domaini413 – 44028C2H2-typeInterPro annotationAdd
BLAST
Domaini441 – 46323C2H2-typeInterPro annotationAdd
BLAST
Domaini486 – 51328C2H2-typeInterPro annotationAdd
BLAST
Domaini514 – 54128C2H2-typeInterPro annotationAdd
BLAST
Domaini542 – 56928C2H2-typeInterPro annotationAdd
BLAST
Domaini570 – 59728C2H2-typeInterPro annotationAdd
BLAST
Domaini598 – 62528C2H2-typeInterPro annotationAdd
BLAST
Domaini626 – 65328C2H2-typeInterPro annotationAdd
BLAST
Domaini654 – 68128C2H2-typeInterPro annotationAdd
BLAST
Domaini682 – 70928C2H2-typeInterPro annotationAdd
BLAST
Domaini710 – 73526C2H2-typeInterPro annotationAdd
BLAST

Sequence similaritiesi

Contains SCAN box domain.SAAS annotation

Keywords - Domaini

RepeatSAAS annotation, Zinc-fingerSAAS annotation

Phylogenomic databases

eggNOGiKOG1721. Eukaryota.
COG5048. LUCA.
GeneTreeiENSGT00730000111047.
HOGENOMiHOG000234619.
HOVERGENiHBG018163.
OrthoDBiEOG7KSX7Q.
TreeFamiTF337913.

Family and domain databases

Gene3Di3.30.160.60. 13 hits.
InterProiIPR008916. Retrov_capsid_C.
IPR003309. SCAN_dom.
IPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view]
PfamiPF02023. SCAN. 1 hit.
PF00096. zf-C2H2. 5 hits.
[Graphical view]
SMARTiSM00431. SCAN. 1 hit.
SM00355. ZnF_C2H2. 13 hits.
[Graphical view]
SUPFAMiSSF47353. SSF47353. 1 hit.
PROSITEiPS50804. SCAN_BOX. 1 hit.
PS00028. ZINC_FINGER_C2H2_1. 13 hits.
PS50157. ZINC_FINGER_C2H2_2. 13 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A1L358-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRPTVLGSSG CAPPENEPAL VKLEDSDSDD EREDILWDPG LEAARLRFRC
60 70 80 90 100
FRYEDAIGPQ EALAQLRELC HQWLRPEVHS KEQVLELLVL EQFLGALPPE
110 120 130 140 150
IQAQVQGQWP GSPEEAAALV DRLRWELDGP RKWVTVQVQG KEVLSEKMEP
160 170 180 190 200
SSFQPRPHIK LQTPDPGAET PQGAMQELPL NLPMKEETEL LGNPELLESG
210 220 230 240 250
PLPAAQEAAA TLLPKETQGH GTTLDQTSPH SDTEPDVPPW SEDPMPLWHE
260 270 280 290 300
EVGGIFSPGF TLQMDSITAE PDMMSPHLHV PWDLDMASLS GQIQSPTTEG
310 320 330 340 350
GFAHALVLPS DPGGEQDPAC EDPCPSVGPA LVATRWHAPR GRSQSHPRSG
360 370 380 390 400
TGAMRGGRCD VCGKVFSQRS NLLRHQKIHT GERPFVCGEC GRSFSRSSHL
410 420 430 440 450
LRHQLTHTEE RPFVCRDCGQ GFVRSARLEE HRRVHTGEQP FRCTECGQSF
460 470 480 490 500
RQRSNLLQHQ RIHGDPPGPA PSILPLAGVP EPPGPFPCSE CCESFPRRAV
510 520 530 540 550
LLEHQAVHTG DKSFGCVECG ERFGRRSVLL QHRRVHSGER PFACAECGQS
560 570 580 590 600
FRQRSNLTQH QRIHTGERPF ACAECGKTFR QRPTLTQHLR VHTGEKPFAC
610 620 630 640 650
PECGQRFSQR LKLTRHQRTH TGEKPYCCGE CGLGFTQVSR LTEHQRIHTG
660 670 680 690 700
ERPFACPECG QSFRQHANLT QHRRIHTGER PYACPECGKA FRQRPTLTQH
710 720 730
LRTHRHEKPF ACQDCGRRFN QSTKLIQHQR VHSTE
Length:735
Mass (Da):82,462
Last modified:February 6, 2007 - v1
Checksum:i23CF252EF3F4C0E2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC121301 Genomic DNA. No translation available.
BC129905 mRNA. Translation: AAI29906.1.
RefSeqiNP_665818.2. NM_145819.2.
UniGeneiMm.10103.

Genome annotation databases

EnsembliENSMUST00000182515; ENSMUSP00000138387; ENSMUSG00000030380.
GeneIDi109889.
UCSCiuc009fff.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC121301 Genomic DNA. No translation available.
BC129905 mRNA. Translation: AAI29906.1.
RefSeqiNP_665818.2. NM_145819.2.
UniGeneiMm.10103.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000069122.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000182515; ENSMUSP00000138387; ENSMUSG00000030380.
GeneIDi109889.
UCSCiuc009fff.2. mouse.

Organism-specific databases

CTDi7593.
MGIiMGI:107457. Mzf1.

Phylogenomic databases

eggNOGiKOG1721. Eukaryota.
COG5048. LUCA.
GeneTreeiENSGT00730000111047.
HOGENOMiHOG000234619.
HOVERGENiHBG018163.
OrthoDBiEOG7KSX7Q.
TreeFamiTF337913.

Miscellaneous databases

NextBioi362959.
SOURCEiSearch...

Family and domain databases

Gene3Di3.30.160.60. 13 hits.
InterProiIPR008916. Retrov_capsid_C.
IPR003309. SCAN_dom.
IPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view]
PfamiPF02023. SCAN. 1 hit.
PF00096. zf-C2H2. 5 hits.
[Graphical view]
SMARTiSM00431. SCAN. 1 hit.
SM00355. ZnF_C2H2. 13 hits.
[Graphical view]
SUPFAMiSSF47353. SSF47353. 1 hit.
PROSITEiPS50804. SCAN_BOX. 1 hit.
PS00028. ZINC_FINGER_C2H2_1. 13 hits.
PS50157. ZINC_FINGER_C2H2_2. 13 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
    , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: PCR rescued clonesImported.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  3. Ensembl
    Submitted (JUL-2013) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiA1L358_MOUSE
AccessioniPrimary (citable) accession number: A1L358
Entry historyi
Integrated into UniProtKB/TrEMBL: February 6, 2007
Last sequence update: February 6, 2007
Last modified: May 11, 2016
This is version 84 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.