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A1L306

- A1L306_HUMAN

UniProt

A1L306 - A1L306_HUMAN

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Protein
Submitted name: TNR protein
Gene
TNR
Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 2 out of 5 - Experimental evidence at transcript leveli

Functioni

GO - Biological processi

  1. associative learning Source: Ensembl
  2. extracellular matrix organization Source: Ensembl
  3. locomotory exploration behavior Source: Ensembl
  4. long-term synaptic potentiation Source: Ensembl
  5. negative regulation of axon extension involved in regeneration Source: Ensembl
  6. negative regulation of cell-cell adhesion Source: Ensembl
  7. negative regulation of synaptic transmission Source: Ensembl
  8. neuromuscular process controlling balance Source: Ensembl
  9. neuron cell-cell adhesion Source: Ensembl
  10. positive regulation of synaptic transmission, glutamatergic Source: Ensembl
  11. positive regulation of transmission of nerve impulse Source: Ensembl
  12. synapse organization Source: Ensembl
  13. telencephalon cell migration Source: Ensembl
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
TNR proteinImported
Gene namesi
Name:TNRImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

  1. cell surface Source: Ensembl
  2. membrane raft Source: Ensembl
  3. perineuronal net Source: Ensembl
  4. proteinaceous extracellular matrix Source: Ensembl
Complete GO annotation...

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA36642.

Expressioni

Gene expression databases

ArrayExpressiA1L306.
BgeeiA1L306.

Structurei

3D structure databases

ProteinModelPortaliA1L306.
SMRiA1L306. Positions 402-670.

Family & Domainsi

Sequence similaritiesi

Contains fibrinogen C-terminal domain.SAAS annotations

Phylogenomic databases

HOVERGENiHBG008949.
KOiK06252.

Family and domain databases

Gene3Di2.60.40.10. 9 hits.
3.90.215.10. 1 hit.
4.10.530.10. 1 hit.
InterProiIPR013032. EGF-like_CS.
IPR013111. EGF_extracell.
IPR014716. Fibrinogen_a/b/g_C_1.
IPR014715. Fibrinogen_a/b/g_C_2.
IPR002181. Fibrinogen_a/b/g_C_dom.
IPR003961. Fibronectin_type3.
IPR013783. Ig-like_fold.
[Graphical view]
PfamiPF07974. EGF_2. 2 hits.
PF00147. Fibrinogen_C. 1 hit.
PF00041. fn3. 9 hits.
[Graphical view]
SMARTiSM00186. FBG. 1 hit.
SM00060. FN3. 9 hits.
[Graphical view]
SUPFAMiSSF49265. SSF49265. 5 hits.
SSF56496. SSF56496. 1 hit.
PROSITEiPS00022. EGF_1. 5 hits.
PS01186. EGF_2. 4 hits.
PS51406. FIBRINOGEN_C_2. 1 hit.
PS50853. FN3. 9 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A1L306-1 [UniParc]FASTAAdd to Basket

« Hide

MGQTSDHESQ VTFTHRINFP KKACPCASSA QVLQELLSRI EMLEREVSVL     50
RDQCNANCCQ ESAATGQLDY IPHCSGHGNF SFESCGCICN EGWFGKNCSE 100
PYCPLGCSSR GVCVDGQCIC DSEYSGDDCS ELRCPTDCSS RGLCVDGECV 150
CEEPYTGEDC RELRCPGDCS GKGRCANGTC LCEEGYVGED CGQRQCLNAC 200
SGRGQCEEGL CVCEEGYQGP DCSAVAPPED LRVAGISDRS IELEWDGPMA 250
VTEYVISYQP TALGGLQLQQ RVPGDWSGVT ITELEPGLTY NISVYAVISN 300
ILSLPITAKV ATHLSTPQGL QFKTITETTV EVQWEPFSFS FDGWEISFIP 350
KNNEGGVIAQ VPSDVTSFNQ TGLKPGEEYI VNVVALKEQA RSPPTSASVS 400
TVIDGPTQIL VRDVSDTVAF VEWIPPRAKV DFILLKYGLV GGEGGRTTFR 450
LQPPLSQYSV QALRPGSRYE VSVSAVRGTN ESDSATTQFT TEIDAPKNLR 500
VGSRTATSLD LEWDNSEAEV QEYKVVYSTL AGEQYHEVLV PRGIGPTTRA 550
TLTDLVPGTE YGVGISAVMN SQQSVPATMN ARTELDSPRD LMVTASSETS 600
ISLIWTKASG PIDHYRITFT PSSGIASEVT VPKDRTSYTL TDLEPGAEYI 650
ISVTAERGRQ QSLESTVDAF TGFRPISHLH FSHVTSSSVN ITWSDPSPPA 700
DRLILNYSPR DEEEEMMEVS LDATKRHAVL MGLQPATEYI VNLVAVHGTV 750
TSEPIVGSIT TGIDPPKDIT ISNVTKDSVM VSWSPPVASF DYYRVSYRPT 800
QVGRLDSSVV PNTVTEFTIT RLNPATEYEI SLNSVRGREE SERICTLVHT 850
AMDNPVDLIA TNITPTEALL QWKAPVGEVE NYVIVLTHFA VAGETILVDG 900
VSEEFRLVDL LPSTHYTATM YATNGPLTSG TISTNFSTLL DPPANLTASE 950
VTRQSALISW QPPRAEIENY VLTYKSTDGS RKELIVDAED TWIRLEGLLE 1000
NTDYTVLLQA AQDTTWSSIT STAFTTGGRV FPHPQDCAQH LMNGDTLSGV 1050
YPIFLNGELS QKLQVYCDMT TDGGGWIVFQ RRQNGQTDFF RKWADYRVGF 1100
GNVEDEFWLG LDNIHRITSQ GRYELRVDMR DGQEAAFASY DRFSVEDSRN 1150
LYKLRIGSYN GTAGDSLSYH QGRPFSTEDR DNDVAVTNCA MSYKGAWWYK 1200
NCHRTNLNGK YGESRHSQGI NWYHWKGHEF SIPFVEMKMR PYNHRLMAGR 1250
KRQSLQF 1257
Length:1,257
Mass (Da):138,577
Last modified:February 6, 2007 - v1
Checksum:iC91D34380A00E43F
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BC129830 mRNA. Translation: AAI29831.1.
RefSeqiNP_003276.3. NM_003285.2.
UniGeneiHs.659864.

Genome annotation databases

GeneIDi7143.
KEGGihsa:7143.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BC129830 mRNA. Translation: AAI29831.1 .
RefSeqi NP_003276.3. NM_003285.2.
UniGenei Hs.659864.

3D structure databases

ProteinModelPortali A1L306.
SMRi A1L306. Positions 402-670.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 7143.
KEGGi hsa:7143.

Organism-specific databases

CTDi 7143.
PharmGKBi PA36642.

Phylogenomic databases

HOVERGENi HBG008949.
KOi K06252.

Miscellaneous databases

GenomeRNAii 7143.
NextBioi 27961.

Gene expression databases

ArrayExpressi A1L306.
Bgeei A1L306.

Family and domain databases

Gene3Di 2.60.40.10. 9 hits.
3.90.215.10. 1 hit.
4.10.530.10. 1 hit.
InterProi IPR013032. EGF-like_CS.
IPR013111. EGF_extracell.
IPR014716. Fibrinogen_a/b/g_C_1.
IPR014715. Fibrinogen_a/b/g_C_2.
IPR002181. Fibrinogen_a/b/g_C_dom.
IPR003961. Fibronectin_type3.
IPR013783. Ig-like_fold.
[Graphical view ]
Pfami PF07974. EGF_2. 2 hits.
PF00147. Fibrinogen_C. 1 hit.
PF00041. fn3. 9 hits.
[Graphical view ]
SMARTi SM00186. FBG. 1 hit.
SM00060. FN3. 9 hits.
[Graphical view ]
SUPFAMi SSF49265. SSF49265. 5 hits.
SSF56496. SSF56496. 1 hit.
PROSITEi PS00022. EGF_1. 5 hits.
PS01186. EGF_2. 4 hits.
PS51406. FIBRINOGEN_C_2. 1 hit.
PS50853. FN3. 9 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
    , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].

Entry informationi

Entry nameiA1L306_HUMAN
AccessioniPrimary (citable) accession number: A1L306
Entry historyi
Integrated into UniProtKB/TrEMBL: February 6, 2007
Last sequence update: February 6, 2007
Last modified: April 16, 2014
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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