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A1L306

- A1L306_HUMAN

UniProt

A1L306 - A1L306_HUMAN

Protein
Submitted name:

TNR protein

Gene

TNR

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 57 (01 Oct 2014)
      Sequence version 1 (06 Feb 2007)
      Previous versions | rss
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    Functioni

    GO - Biological processi

    1. associative learning Source: Ensembl
    2. extracellular matrix organization Source: Ensembl
    3. locomotory exploration behavior Source: Ensembl
    4. long-term synaptic potentiation Source: Ensembl
    5. negative regulation of axon extension involved in regeneration Source: Ensembl
    6. negative regulation of cell-cell adhesion Source: Ensembl
    7. negative regulation of synaptic transmission Source: Ensembl
    8. neuromuscular process controlling balance Source: Ensembl
    9. neuron cell-cell adhesion Source: Ensembl
    10. positive regulation of synaptic transmission, glutamatergic Source: Ensembl
    11. positive regulation of transmission of nerve impulse Source: Ensembl
    12. synapse organization Source: Ensembl
    13. telencephalon cell migration Source: Ensembl

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    TNR proteinImported
    Gene namesi
    Name:TNRImported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

    Subcellular locationi

    GO - Cellular componenti

    1. cell surface Source: Ensembl
    2. membrane raft Source: Ensembl
    3. perineuronal net Source: Ensembl
    4. proteinaceous extracellular matrix Source: Ensembl

    Pathology & Biotechi

    Organism-specific databases

    PharmGKBiPA36642.

    Expressioni

    Gene expression databases

    ArrayExpressiA1L306.
    BgeeiA1L306.

    Structurei

    3D structure databases

    ProteinModelPortaliA1L306.
    SMRiA1L306. Positions 402-670.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Contains fibrinogen C-terminal domain.SAAS annotation

    Phylogenomic databases

    HOVERGENiHBG008949.
    KOiK06252.

    Family and domain databases

    Gene3Di2.60.40.10. 9 hits.
    3.90.215.10. 1 hit.
    4.10.530.10. 1 hit.
    InterProiIPR013032. EGF-like_CS.
    IPR013111. EGF_extracell.
    IPR014716. Fibrinogen_a/b/g_C_1.
    IPR014715. Fibrinogen_a/b/g_C_2.
    IPR002181. Fibrinogen_a/b/g_C_dom.
    IPR003961. Fibronectin_type3.
    IPR013783. Ig-like_fold.
    [Graphical view]
    PfamiPF07974. EGF_2. 2 hits.
    PF00147. Fibrinogen_C. 1 hit.
    PF00041. fn3. 9 hits.
    [Graphical view]
    SMARTiSM00186. FBG. 1 hit.
    SM00060. FN3. 9 hits.
    [Graphical view]
    SUPFAMiSSF49265. SSF49265. 5 hits.
    SSF56496. SSF56496. 1 hit.
    PROSITEiPS00022. EGF_1. 5 hits.
    PS01186. EGF_2. 4 hits.
    PS51406. FIBRINOGEN_C_2. 1 hit.
    PS50853. FN3. 9 hits.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    A1L306-1 [UniParc]FASTAAdd to Basket

    « Hide

    MGQTSDHESQ VTFTHRINFP KKACPCASSA QVLQELLSRI EMLEREVSVL     50
    RDQCNANCCQ ESAATGQLDY IPHCSGHGNF SFESCGCICN EGWFGKNCSE 100
    PYCPLGCSSR GVCVDGQCIC DSEYSGDDCS ELRCPTDCSS RGLCVDGECV 150
    CEEPYTGEDC RELRCPGDCS GKGRCANGTC LCEEGYVGED CGQRQCLNAC 200
    SGRGQCEEGL CVCEEGYQGP DCSAVAPPED LRVAGISDRS IELEWDGPMA 250
    VTEYVISYQP TALGGLQLQQ RVPGDWSGVT ITELEPGLTY NISVYAVISN 300
    ILSLPITAKV ATHLSTPQGL QFKTITETTV EVQWEPFSFS FDGWEISFIP 350
    KNNEGGVIAQ VPSDVTSFNQ TGLKPGEEYI VNVVALKEQA RSPPTSASVS 400
    TVIDGPTQIL VRDVSDTVAF VEWIPPRAKV DFILLKYGLV GGEGGRTTFR 450
    LQPPLSQYSV QALRPGSRYE VSVSAVRGTN ESDSATTQFT TEIDAPKNLR 500
    VGSRTATSLD LEWDNSEAEV QEYKVVYSTL AGEQYHEVLV PRGIGPTTRA 550
    TLTDLVPGTE YGVGISAVMN SQQSVPATMN ARTELDSPRD LMVTASSETS 600
    ISLIWTKASG PIDHYRITFT PSSGIASEVT VPKDRTSYTL TDLEPGAEYI 650
    ISVTAERGRQ QSLESTVDAF TGFRPISHLH FSHVTSSSVN ITWSDPSPPA 700
    DRLILNYSPR DEEEEMMEVS LDATKRHAVL MGLQPATEYI VNLVAVHGTV 750
    TSEPIVGSIT TGIDPPKDIT ISNVTKDSVM VSWSPPVASF DYYRVSYRPT 800
    QVGRLDSSVV PNTVTEFTIT RLNPATEYEI SLNSVRGREE SERICTLVHT 850
    AMDNPVDLIA TNITPTEALL QWKAPVGEVE NYVIVLTHFA VAGETILVDG 900
    VSEEFRLVDL LPSTHYTATM YATNGPLTSG TISTNFSTLL DPPANLTASE 950
    VTRQSALISW QPPRAEIENY VLTYKSTDGS RKELIVDAED TWIRLEGLLE 1000
    NTDYTVLLQA AQDTTWSSIT STAFTTGGRV FPHPQDCAQH LMNGDTLSGV 1050
    YPIFLNGELS QKLQVYCDMT TDGGGWIVFQ RRQNGQTDFF RKWADYRVGF 1100
    GNVEDEFWLG LDNIHRITSQ GRYELRVDMR DGQEAAFASY DRFSVEDSRN 1150
    LYKLRIGSYN GTAGDSLSYH QGRPFSTEDR DNDVAVTNCA MSYKGAWWYK 1200
    NCHRTNLNGK YGESRHSQGI NWYHWKGHEF SIPFVEMKMR PYNHRLMAGR 1250
    KRQSLQF 1257
    Length:1,257
    Mass (Da):138,577
    Last modified:February 6, 2007 - v1
    Checksum:iC91D34380A00E43F
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC129830 mRNA. Translation: AAI29831.1.
    RefSeqiNP_003276.3. NM_003285.2.
    UniGeneiHs.659864.

    Genome annotation databases

    GeneIDi7143.
    KEGGihsa:7143.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC129830 mRNA. Translation: AAI29831.1 .
    RefSeqi NP_003276.3. NM_003285.2.
    UniGenei Hs.659864.

    3D structure databases

    ProteinModelPortali A1L306.
    SMRi A1L306. Positions 402-670.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 7143.
    KEGGi hsa:7143.

    Organism-specific databases

    CTDi 7143.
    PharmGKBi PA36642.

    Phylogenomic databases

    HOVERGENi HBG008949.
    KOi K06252.

    Miscellaneous databases

    GenomeRNAii 7143.
    NextBioi 27961.

    Gene expression databases

    ArrayExpressi A1L306.
    Bgeei A1L306.

    Family and domain databases

    Gene3Di 2.60.40.10. 9 hits.
    3.90.215.10. 1 hit.
    4.10.530.10. 1 hit.
    InterProi IPR013032. EGF-like_CS.
    IPR013111. EGF_extracell.
    IPR014716. Fibrinogen_a/b/g_C_1.
    IPR014715. Fibrinogen_a/b/g_C_2.
    IPR002181. Fibrinogen_a/b/g_C_dom.
    IPR003961. Fibronectin_type3.
    IPR013783. Ig-like_fold.
    [Graphical view ]
    Pfami PF07974. EGF_2. 2 hits.
    PF00147. Fibrinogen_C. 1 hit.
    PF00041. fn3. 9 hits.
    [Graphical view ]
    SMARTi SM00186. FBG. 1 hit.
    SM00060. FN3. 9 hits.
    [Graphical view ]
    SUPFAMi SSF49265. SSF49265. 5 hits.
    SSF56496. SSF56496. 1 hit.
    PROSITEi PS00022. EGF_1. 5 hits.
    PS01186. EGF_2. 4 hits.
    PS51406. FIBRINOGEN_C_2. 1 hit.
    PS50853. FN3. 9 hits.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
      , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].

    Entry informationi

    Entry nameiA1L306_HUMAN
    AccessioniPrimary (citable) accession number: A1L306
    Entry historyi
    Integrated into UniProtKB/TrEMBL: February 6, 2007
    Last sequence update: February 6, 2007
    Last modified: October 1, 2014
    This is version 57 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.