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Protein

Structural maintenance of chromosomes protein

Gene

Smc1b

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Structural maintenance of chromosomes proteinUniRule annotation
Gene namesi
Name:Smc1bImported
ORF Names:mCG_117302Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:2154049. Smc1b.

Subcellular locationi

  • Nucleus UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

NucleusUniRule annotation

Expressioni

Gene expression databases

BgeeiENSMUSG00000022432.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000023068.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini513 – 629SMC_hingeInterPro annotationAdd BLAST117

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili365 – 441Sequence analysisAdd BLAST77
Coiled coili446 – 483Sequence analysisAdd BLAST38
Coiled coili671 – 702Sequence analysisAdd BLAST32
Coiled coili789 – 818Sequence analysisAdd BLAST30
Coiled coili835 – 872Sequence analysisAdd BLAST38

Sequence similaritiesi

Belongs to the SMC family.UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG0018. Eukaryota.
COG1196. LUCA.
HOVERGENiHBG039593.
KOiK06636.
OMAiISMKKPK.
OrthoDBiEOG091G00R5.

Family and domain databases

Gene3Di3.40.50.300. 3 hits.
InterProiIPR027417. P-loop_NTPase.
IPR003395. RecF/RecN/SMC_N.
IPR024704. SMC.
IPR010935. SMC_hinge.
[Graphical view]
PfamiPF06470. SMC_hinge. 1 hit.
PF02463. SMC_N. 1 hit.
[Graphical view]
PIRSFiPIRSF005719. SMC. 1 hit.
SMARTiSM00968. SMC_hinge. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 4 hits.
SSF75553. SSF75553. 1 hit.

Sequencei

Sequence statusi: Complete.

A1L2Z0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGHLELLLVE NFKSWRGRQV IGPFKRFTCI IGPNGSGKSN VMDALSFVMG
60 70 80 90 100
EKTTNLRVKN IQELIHGAHT GKPVSSSASV TIIYIEDSGE EKTFTRIIRG
110 120 130 140 150
GCSEYHFGDK PVSRSVYVAQ LENIGIIVKA QNCLVFQGTV ESISMKKPKE
160 170 180 190 200
RTQFFEEIST SGEFIGEYEA KKKKLQKAEE DAQFHFNVKK NVAAERKHAK
210 220 230 240 250
IEKEEAEHYQ NLLEELKINK IQLMLFQLYY NEEKINVLNT ELEQMDGNLS
260 270 280 290 300
VVKDTLSHHE NIFKAKKKDY GMLTRQLQQT AKELKSVEAI LNQKRPQYIK
310 320 330 340 350
AKENTSHHLK KLDLSKKLIT DNEKQCSKQE DGIRALVAEL ADLDRAWKSF
360 370 380 390 400
EKQMEEKILQ KGRDIELENS QLDRYKLLKE QVRRKVGIMT QQLEKLQWEQ
410 420 430 440 450
KAEKERLAFE KRRHGDTQGN LKQIKEQIEE HKKRIEKLEE YTKTCMDCLE
460 470 480 490 500
DKKQQEEALK KEIENTKSRM SEVNEELSLI RNELQNAGID NHEGKRQQKR
510 520 530 540 550
AEVLEHLKRL YPDSVFGRLL DLCHPIHKKY QLAVTKLFGR YMVAIVVASE
560 570 580 590 600
KIAKDCIRFL KAERAEPETF LALDYLDIKP INERLREIKG CKMMIDVIKT
610 620 630 640 650
QFPQLKKVIQ FVCGNGLVCE TVEEARHIAF GGPERRKAVA LDGTLFLKSG
660 670 680 690 700
VISGGSSDLK HKALCWDEKE LHNLRDKRSQ LVQELKELMK TLRKETDLKQ
710 720 730 740 750
IQTLVQGTNT RLKYSQNELE MIKKKHLATF YREQSQLQSE LLNIDSQCTM
760 770 780 790 800
LSEGINKQQQ KIEEFQDKID EVEDDIFQDF CEEIGVENIR EFENKHVKQQ
810 820 830 840 850
QENDQKRLEF EKQKTRLNIQ LEYSRNQLKK KLNNIDTLKT TIQKGKEDID
860 870 880 890 900
NLKKTEEECL KIVEELMVKQ EQIKEVLATQ SSNIEKIHIQ IEEERKKVLA
910 920 930 940 950
VDREVGKLQK EVVIIQGSLE QKLLEKHNLL LDCKVQDIDI SLVLGSLEDI
960 970 980 990 1000
IEMELTETES TQATADIYEK EASIQIDYSP LREDLKALQS DKEVEAHLTL
1010 1020 1030 1040 1050
LLQQVASQEN TLLKTTAPNL RAQENLKTVR DKFQESADVF EASRKEARIC
1060 1070 1080 1090 1100
RQEFEQVKRR RYDAFSQCFE HISVSIDQIY KKLCRNNSAQ AFLSPENPEE
1110 1120 1130 1140 1150
PYLDGISYNC VAPGKRFMPM DNLSGGEKCV AALALLFAVH SFRPAPFFVL
1160 1170 1180 1190 1200
DEVDAALDNT NIGKVSSYIK EQSQEQFQMI IISLKEEFYS KADALIGVYP
1210 1220 1230 1240
EHNECMFSHV LTLDLSKYPD TEDQEGSRSH RKPRVPRVSM SPKSPQSR
Length:1,248
Mass (Da):144,513
Last modified:February 6, 2007 - v1
Checksum:i6C31DB46217BC94D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC129800 mRNA. Translation: AAI29801.1.
CH466550 Genomic DNA. Translation: EDL04440.1.
RefSeqiNP_536718.1. NM_080470.1.
UniGeneiMm.182737.

Genome annotation databases

GeneIDi140557.
KEGGimmu:140557.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC129800 mRNA. Translation: AAI29801.1.
CH466550 Genomic DNA. Translation: EDL04440.1.
RefSeqiNP_536718.1. NM_080470.1.
UniGeneiMm.182737.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000023068.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi140557.
KEGGimmu:140557.

Organism-specific databases

CTDi27127.
MGIiMGI:2154049. Smc1b.

Phylogenomic databases

eggNOGiKOG0018. Eukaryota.
COG1196. LUCA.
HOVERGENiHBG039593.
KOiK06636.
OMAiISMKKPK.
OrthoDBiEOG091G00R5.

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000022432.

Family and domain databases

Gene3Di3.40.50.300. 3 hits.
InterProiIPR027417. P-loop_NTPase.
IPR003395. RecF/RecN/SMC_N.
IPR024704. SMC.
IPR010935. SMC_hinge.
[Graphical view]
PfamiPF06470. SMC_hinge. 1 hit.
PF02463. SMC_N. 1 hit.
[Graphical view]
PIRSFiPIRSF005719. SMC. 1 hit.
SMARTiSM00968. SMC_hinge. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 4 hits.
SSF75553. SSF75553. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiA1L2Z0_MOUSE
AccessioniPrimary (citable) accession number: A1L2Z0
Entry historyi
Integrated into UniProtKB/TrEMBL: February 6, 2007
Last sequence update: February 6, 2007
Last modified: November 30, 2016
This is version 88 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.