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A1L2U9

- ZB8AB_XENLA

UniProt

A1L2U9 - ZB8AB_XENLA

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Protein

Zinc finger and BTB domain-containing protein 8A.1-B

Gene

zbtb8a.1-b

Organism
Xenopus laevis (African clawed frog)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli

Functioni

May be involved in transcriptional regulation.

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri315 – 33723C2H2-type 1PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri343 – 36624C2H2-type 2PROSITE-ProRule annotationAdd
BLAST

GO - Molecular functioni

  1. DNA binding Source: UniProtKB-KW
  2. metal ion binding Source: UniProtKB-KW

GO - Biological processi

  1. regulation of transcription, DNA-templated Source: UniProtKB-KW
  2. transcription, DNA-templated Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding, Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Zinc finger and BTB domain-containing protein 8A.1-B
Gene namesi
Name:zbtb8a.1-b
OrganismiXenopus laevis (African clawed frog)
Taxonomic identifieri8355 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusXenopus

Organism-specific databases

XenbaseiXB-GENE-6255849. zbtb8a.1.

Subcellular locationi

Nucleus Curated

GO - Cellular componenti

  1. nucleus Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 469469Zinc finger and BTB domain-containing protein 8A.1-BPRO_0000378512Add
BLAST

Keywords - PTMi

Phosphoprotein

Structurei

3D structure databases

ProteinModelPortaliA1L2U9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini24 – 9269BTBPROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Contains 1 BTB (POZ) domain.PROSITE-ProRule annotation
Contains 2 C2H2-type zinc fingers.PROSITE-ProRule annotation

Zinc finger

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri315 – 33723C2H2-type 1PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri343 – 36624C2H2-type 2PROSITE-ProRule annotationAdd
BLAST

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

KOiK10495.

Family and domain databases

Gene3Di3.30.160.60. 2 hits.
3.30.710.10. 1 hit.
InterProiIPR000210. BTB/POZ-like.
IPR011333. BTB/POZ_fold.
IPR013069. BTB_POZ.
IPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view]
PfamiPF00651. BTB. 1 hit.
[Graphical view]
SMARTiSM00225. BTB. 1 hit.
SM00355. ZnF_C2H2. 2 hits.
[Graphical view]
SUPFAMiSSF54695. SSF54695. 1 hit.
PROSITEiPS50097. BTB. 1 hit.
PS00028. ZINC_FINGER_C2H2_1. 2 hits.
PS50157. ZINC_FINGER_C2H2_2. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A1L2U9-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MEFSSHHIRL LQQLDEQRRR DLFCDCHIIV EGQMFKAHRN VLFASSGYFK
60 70 80 90 100
MLLSQSCRDM GEPITATFDV FSADTFTAIL DFVYSGKLPL SGQNVIEVMS
110 120 130 140 150
AASYLQMTDV IGVCKMFIKS SLDINEKDRD GFFSLSDKDT DSNGSGLYAA
160 170 180 190 200
GWRTESSPTH THKTTEHGSF IAGYNYPPPI SSRLQHPFSK SPRKPELVRK
210 220 230 240 250
HRRRLLPEAL TPALSHIPLG DLVGGSTECM LHDEETVESV SQEEERTQTQ
260 270 280 290 300
VSIISIKVED LDATSNSWPE SPPQESLDQG SALHITKAEE LYKAMPTILG
310 320 330 340 350
GVSGWGEDEL SSGRFKCPFC THTVKRKADL KRHLRCHTGE RPYPCEACGK
360 370 380 390 400
RFTRLEHLRN HFQTIHEAGK LICRRCKLPV TKVTGRVIQD GTRRYRLCQA
410 420 430 440 450
CLAEAGLDNV NFDYGEDQPL VLPPENEREH CWNFKEEGRQ ENGSEAAESD
460
LVIQEVVDSE EDELKQKQD
Length:469
Mass (Da):52,998
Last modified:February 6, 2007 - v1
Checksum:iBA2B6D07F4AAB559
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BC129718 mRNA. Translation: AAI29719.1.
RefSeqiNP_001091193.1. NM_001097724.1.
UniGeneiXl.75030.

Genome annotation databases

GeneIDi100036960.
KEGGixla:100036960.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BC129718 mRNA. Translation: AAI29719.1 .
RefSeqi NP_001091193.1. NM_001097724.1.
UniGenei Xl.75030.

3D structure databases

ProteinModelPortali A1L2U9.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 100036960.
KEGGi xla:100036960.

Organism-specific databases

CTDi 100036960.
Xenbasei XB-GENE-6255849. zbtb8a.1.

Phylogenomic databases

KOi K10495.

Family and domain databases

Gene3Di 3.30.160.60. 2 hits.
3.30.710.10. 1 hit.
InterProi IPR000210. BTB/POZ-like.
IPR011333. BTB/POZ_fold.
IPR013069. BTB_POZ.
IPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view ]
Pfami PF00651. BTB. 1 hit.
[Graphical view ]
SMARTi SM00225. BTB. 1 hit.
SM00355. ZnF_C2H2. 2 hits.
[Graphical view ]
SUPFAMi SSF54695. SSF54695. 1 hit.
PROSITEi PS50097. BTB. 1 hit.
PS00028. ZINC_FINGER_C2H2_1. 2 hits.
PS50157. ZINC_FINGER_C2H2_2. 2 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. NIH - Xenopus Gene Collection (XGC) project
    Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Thymus.

Entry informationi

Entry nameiZB8AB_XENLA
AccessioniPrimary (citable) accession number: A1L2U9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 7, 2009
Last sequence update: February 6, 2007
Last modified: October 29, 2014
This is version 47 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3