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A1L2U9 (ZB8AB_XENLA) Reviewed, UniProtKB/Swiss-Prot

Last modified April 3, 2013. Version 43. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Zinc finger and BTB domain-containing protein 8A.1-B
Gene names
Name:zbtb8a.1-b
OrganismXenopus laevis (African clawed frog)
Taxonomic identifier8355 [NCBI]
Taxonomic lineageEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Amphibia › Batrachia › Anura › Pipoidea › Pipidae › Xenopodinae › Xenopus › Xenopus

Protein attributes

Sequence length469 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

May be involved in transcriptional regulation.

Subcellular location

Nucleus Potential.

Sequence similarities

Contains 1 BTB (POZ) domain.

Contains 2 C2H2-type zinc fingers.

Ontologies

Keywords
   Biological processTranscription
Transcription regulation
   Cellular componentNucleus
   DomainRepeat
Zinc-finger
   LigandDNA-binding
Metal-binding
Zinc
   PTMPhosphoprotein
Gene Ontology (GO)
   Biological_processregulation of transcription, DNA-dependent

Inferred from electronic annotation. Source: UniProtKB-KW

transcription, DNA-dependent

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular_componentnucleus

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionDNA binding

Inferred from electronic annotation. Source: UniProtKB-KW

zinc ion binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 469469Zinc finger and BTB domain-containing protein 8A.1-B
PRO_0000378512

Regions

Domain24 – 9269BTB
Zinc finger315 – 33723C2H2-type 1
Zinc finger343 – 36624C2H2-type 2

Sequences

Sequence LengthMass (Da)Tools
A1L2U9 [UniParc].

Last modified February 6, 2007. Version 1.
Checksum: BA2B6D07F4AAB559

FASTA46952,998
        10         20         30         40         50         60 
MEFSSHHIRL LQQLDEQRRR DLFCDCHIIV EGQMFKAHRN VLFASSGYFK MLLSQSCRDM 

        70         80         90        100        110        120 
GEPITATFDV FSADTFTAIL DFVYSGKLPL SGQNVIEVMS AASYLQMTDV IGVCKMFIKS 

       130        140        150        160        170        180 
SLDINEKDRD GFFSLSDKDT DSNGSGLYAA GWRTESSPTH THKTTEHGSF IAGYNYPPPI 

       190        200        210        220        230        240 
SSRLQHPFSK SPRKPELVRK HRRRLLPEAL TPALSHIPLG DLVGGSTECM LHDEETVESV 

       250        260        270        280        290        300 
SQEEERTQTQ VSIISIKVED LDATSNSWPE SPPQESLDQG SALHITKAEE LYKAMPTILG 

       310        320        330        340        350        360 
GVSGWGEDEL SSGRFKCPFC THTVKRKADL KRHLRCHTGE RPYPCEACGK RFTRLEHLRN 

       370        380        390        400        410        420 
HFQTIHEAGK LICRRCKLPV TKVTGRVIQD GTRRYRLCQA CLAEAGLDNV NFDYGEDQPL 

       430        440        450        460 
VLPPENEREH CWNFKEEGRQ ENGSEAAESD LVIQEVVDSE EDELKQKQD

« Hide

References

[1]NIH - Xenopus Gene Collection (XGC) project
Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Thymus.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		BC129718 mRNA. Translation: AAI29719.1.
RefSeqNP_001091193.1. NM_001097724.1.
UniGeneXl.75030.

3D structure databases

ProteinModelPortalA1L2U9.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID100036960.
KEGGxla:100036960.

Organism-specific databases

CTD100036960.
XenbaseXB-GENE-6255849. zbtb8a.1.

Phylogenomic databases

KOK10495.

Family and domain databases

Gene3D3.30.160.60. 2 hits.
3.30.710.10. 1 hit.
InterProIPR000210. BTB/POZ-like.
IPR011333. BTB/POZ_fold.
IPR013069. BTB_POZ.
IPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view]
PfamPF00651. BTB. 1 hit.
[Graphical view]
SMARTSM00225. BTB. 1 hit.
SM00355. ZnF_C2H2. 2 hits.
[Graphical view]
SUPFAMSSF54695. BTB/POZ_fold. 1 hit.
PROSITEPS50097. BTB. 1 hit.
PS00028. ZINC_FINGER_C2H2_1. 2 hits.
PS50157. ZINC_FINGER_C2H2_2. 2 hits.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameZB8AB_XENLA
AccessionPrimary (citable) accession number: A1L2U9
Entry history
Integrated into UniProtKB/Swiss-Prot: July 7, 2009
Last sequence update: February 6, 2007
Last modified: April 3, 2013
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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