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A1L2U9

- ZB8AB_XENLA

UniProt

A1L2U9 - ZB8AB_XENLA

Protein

Zinc finger and BTB domain-containing protein 8A.1-B

Gene

zbtb8a.1-b

Organism
Xenopus laevis (African clawed frog)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 46 (01 Oct 2014)
      Sequence version 1 (06 Feb 2007)
      Previous versions | rss
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    • Comment

    Functioni

    May be involved in transcriptional regulation.

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Zinc fingeri315 – 33723C2H2-type 1PROSITE-ProRule annotationAdd
    BLAST
    Zinc fingeri343 – 36624C2H2-type 2PROSITE-ProRule annotationAdd
    BLAST

    GO - Molecular functioni

    1. DNA binding Source: UniProtKB-KW
    2. metal ion binding Source: UniProtKB-KW

    GO - Biological processi

    1. regulation of transcription, DNA-templated Source: UniProtKB-KW
    2. transcription, DNA-templated Source: UniProtKB-KW

    Keywords - Biological processi

    Transcription, Transcription regulation

    Keywords - Ligandi

    DNA-binding, Metal-binding, Zinc

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Zinc finger and BTB domain-containing protein 8A.1-B
    Gene namesi
    Name:zbtb8a.1-b
    OrganismiXenopus laevis (African clawed frog)
    Taxonomic identifieri8355 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusXenopus

    Organism-specific databases

    XenbaseiXB-GENE-6255849. zbtb8a.1.

    Subcellular locationi

    Nucleus Curated

    GO - Cellular componenti

    1. nucleus Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Nucleus

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 469469Zinc finger and BTB domain-containing protein 8A.1-BPRO_0000378512Add
    BLAST

    Keywords - PTMi

    Phosphoprotein

    Structurei

    3D structure databases

    ProteinModelPortaliA1L2U9.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini24 – 9269BTBPROSITE-ProRule annotationAdd
    BLAST

    Sequence similaritiesi

    Contains 1 BTB (POZ) domain.PROSITE-ProRule annotation
    Contains 2 C2H2-type zinc fingers.PROSITE-ProRule annotation

    Zinc finger

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Zinc fingeri315 – 33723C2H2-type 1PROSITE-ProRule annotationAdd
    BLAST
    Zinc fingeri343 – 36624C2H2-type 2PROSITE-ProRule annotationAdd
    BLAST

    Keywords - Domaini

    Repeat, Zinc-finger

    Phylogenomic databases

    KOiK10495.

    Family and domain databases

    Gene3Di3.30.160.60. 2 hits.
    3.30.710.10. 1 hit.
    InterProiIPR000210. BTB/POZ-like.
    IPR011333. BTB/POZ_fold.
    IPR013069. BTB_POZ.
    IPR007087. Znf_C2H2.
    IPR015880. Znf_C2H2-like.
    IPR013087. Znf_C2H2/integrase_DNA-bd.
    [Graphical view]
    PfamiPF00651. BTB. 1 hit.
    [Graphical view]
    SMARTiSM00225. BTB. 1 hit.
    SM00355. ZnF_C2H2. 2 hits.
    [Graphical view]
    SUPFAMiSSF54695. SSF54695. 1 hit.
    PROSITEiPS50097. BTB. 1 hit.
    PS00028. ZINC_FINGER_C2H2_1. 2 hits.
    PS50157. ZINC_FINGER_C2H2_2. 2 hits.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    A1L2U9-1 [UniParc]FASTAAdd to Basket

    « Hide

    MEFSSHHIRL LQQLDEQRRR DLFCDCHIIV EGQMFKAHRN VLFASSGYFK    50
    MLLSQSCRDM GEPITATFDV FSADTFTAIL DFVYSGKLPL SGQNVIEVMS 100
    AASYLQMTDV IGVCKMFIKS SLDINEKDRD GFFSLSDKDT DSNGSGLYAA 150
    GWRTESSPTH THKTTEHGSF IAGYNYPPPI SSRLQHPFSK SPRKPELVRK 200
    HRRRLLPEAL TPALSHIPLG DLVGGSTECM LHDEETVESV SQEEERTQTQ 250
    VSIISIKVED LDATSNSWPE SPPQESLDQG SALHITKAEE LYKAMPTILG 300
    GVSGWGEDEL SSGRFKCPFC THTVKRKADL KRHLRCHTGE RPYPCEACGK 350
    RFTRLEHLRN HFQTIHEAGK LICRRCKLPV TKVTGRVIQD GTRRYRLCQA 400
    CLAEAGLDNV NFDYGEDQPL VLPPENEREH CWNFKEEGRQ ENGSEAAESD 450
    LVIQEVVDSE EDELKQKQD 469
    Length:469
    Mass (Da):52,998
    Last modified:February 6, 2007 - v1
    Checksum:iBA2B6D07F4AAB559
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC129718 mRNA. Translation: AAI29719.1.
    RefSeqiNP_001091193.1. NM_001097724.1.
    UniGeneiXl.75030.

    Genome annotation databases

    GeneIDi100036960.
    KEGGixla:100036960.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC129718 mRNA. Translation: AAI29719.1 .
    RefSeqi NP_001091193.1. NM_001097724.1.
    UniGenei Xl.75030.

    3D structure databases

    ProteinModelPortali A1L2U9.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 100036960.
    KEGGi xla:100036960.

    Organism-specific databases

    CTDi 100036960.
    Xenbasei XB-GENE-6255849. zbtb8a.1.

    Phylogenomic databases

    KOi K10495.

    Family and domain databases

    Gene3Di 3.30.160.60. 2 hits.
    3.30.710.10. 1 hit.
    InterProi IPR000210. BTB/POZ-like.
    IPR011333. BTB/POZ_fold.
    IPR013069. BTB_POZ.
    IPR007087. Znf_C2H2.
    IPR015880. Znf_C2H2-like.
    IPR013087. Znf_C2H2/integrase_DNA-bd.
    [Graphical view ]
    Pfami PF00651. BTB. 1 hit.
    [Graphical view ]
    SMARTi SM00225. BTB. 1 hit.
    SM00355. ZnF_C2H2. 2 hits.
    [Graphical view ]
    SUPFAMi SSF54695. SSF54695. 1 hit.
    PROSITEi PS50097. BTB. 1 hit.
    PS00028. ZINC_FINGER_C2H2_1. 2 hits.
    PS50157. ZINC_FINGER_C2H2_2. 2 hits.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. NIH - Xenopus Gene Collection (XGC) project
      Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: Thymus.

    Entry informationi

    Entry nameiZB8AB_XENLA
    AccessioniPrimary (citable) accession number: A1L2U9
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: July 7, 2009
    Last sequence update: February 6, 2007
    Last modified: October 1, 2014
    This is version 46 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program

    Miscellaneousi

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3