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A1L2T6

- ZCHC7_XENLA

UniProt

A1L2T6 - ZCHC7_XENLA

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Protein

Zinc finger CCHC domain-containing protein 7

Gene

zcchc7

Organism
Xenopus laevis (African clawed frog)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli

Functioni

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri265 – 28218CCHC-type 1PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri287 – 30418CCHC-type 2PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri305 – 32218CCHC-type 3PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri328 – 34518CCHC-type 4PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri372 – 38918CCHC-type 5PROSITE-ProRule annotationAdd
BLAST

GO - Molecular functioni

  1. nucleic acid binding Source: InterPro
  2. zinc ion binding Source: InterPro
Complete GO annotation...

Keywords - Ligandi

Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Zinc finger CCHC domain-containing protein 7
Alternative name(s):
TRAMP-like complex RNA-binding factor ZCCHC7
Gene namesi
Name:zcchc7
OrganismiXenopus laevis (African clawed frog)
Taxonomic identifieri8355 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusXenopus

Organism-specific databases

XenbaseiXB-GENE-6255854. zcchc7.

Subcellular locationi

Nucleusnucleolus By similarity

GO - Cellular componenti

  1. nucleus Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 563563Zinc finger CCHC domain-containing protein 7PRO_0000370243Add
BLAST

Interactioni

Subunit structurei

Component of a nucleolar TRAMP-like complex, an ATP-dependent exosome regulatory complex consisting of an helicase (SKIV2L2/MTR4), an oligadenylate polymerase (PAPD5 or PAPD7), and a substrate specific RNA-binding factor (ZCCHC7 or ZCCHC8). Several TRAMP-like complexes exist with specific compositions and are associated with nuclear, or nucleolar RNA exosomes (By similarity).By similarity

Family & Domainsi

Sequence similaritiesi

Contains 5 CCHC-type zinc fingers.PROSITE-ProRule annotation

Zinc finger

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri265 – 28218CCHC-type 1PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri287 – 30418CCHC-type 2PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri305 – 32218CCHC-type 3PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri328 – 34518CCHC-type 4PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri372 – 38918CCHC-type 5PROSITE-ProRule annotationAdd
BLAST

Keywords - Domaini

Repeat, Zinc-finger

Family and domain databases

Gene3Di4.10.60.10. 4 hits.
InterProiIPR001878. Znf_CCHC.
[Graphical view]
PfamiPF00098. zf-CCHC. 1 hit.
[Graphical view]
SMARTiSM00343. ZnF_C2HC. 5 hits.
[Graphical view]
SUPFAMiSSF57756. SSF57756. 2 hits.
PROSITEiPS50158. ZF_CCHC. 3 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A1L2T6-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MFNCDEDLKA YEDELYHEET SSDESIDSEL EFHLYSQVHY SQNLSESKPE
60 70 80 90 100
EDTGGDSVTY VPGAKQQNNA CTEKDDKLVD IIILSDSDAK VSDTCPVIIL
110 120 130 140 150
SDTTEEDSVY SSKIKKKYSS TYVQGESLCG PCSHSTPKVS APQSNNFKSQ
160 170 180 190 200
KSCQNSSSKN YSGGYVQEVL VIRGSSEDEE ANKSENDIII SESDMSDVEN
210 220 230 240 250
WMLLGRAKED GDASIQLNLE GYKILSDDEG ERGAAWSISE KDVEAQIGNY
260 270 280 290 300
TPLRRSNRYY TDKNVVCRNC DKRGHLSKNC PVPKKLPACC LCGERGHYQN
310 320 330 340 350
SCPSRYCLNC FLPGHFFKEC IERAYWRKTC HRCSMPGHYA DACPEIWRQY
360 370 380 390 400
HLTIKAGPIK KPKSHSGQKD IVYCCNCAKK GHCIYECKER RMNSDKLPTC
410 420 430 440 450
QLVFSYDHEY DIRKRNERTK SKIKDFQKAG LLTCEMREFS ESKVDAKPPA
460 470 480 490 500
KKRKKKHPSK KERKGTIRDY ECAETKQKKK HKKRKSGLQE IEGDFPRGIP
510 520 530 540 550
NSYVELKKPS KKYDGSFLHL DKTKDMFKNR QKKTRRGKRC SSAVDQDLLI
560
IKQKKKKSKR KVA
Length:563
Mass (Da):64,410
Last modified:April 14, 2009 - v2
Checksum:i4D4C83EBFBB177D6
GO

Sequence cautioni

The sequence AAI29702.1 differs from that shown. Reason: Erroneous initiation. Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC129701 mRNA. Translation: AAI29702.1. Different initiation.
UniGeneiXl.19467.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC129701 mRNA. Translation: AAI29702.1 . Different initiation.
UniGenei Xl.19467.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Organism-specific databases

Xenbasei XB-GENE-6255854. zcchc7.

Family and domain databases

Gene3Di 4.10.60.10. 4 hits.
InterProi IPR001878. Znf_CCHC.
[Graphical view ]
Pfami PF00098. zf-CCHC. 1 hit.
[Graphical view ]
SMARTi SM00343. ZnF_C2HC. 5 hits.
[Graphical view ]
SUPFAMi SSF57756. SSF57756. 2 hits.
PROSITEi PS50158. ZF_CCHC. 3 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. NIH - Xenopus Gene Collection (XGC) project
    Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Thymus.

Entry informationi

Entry nameiZCHC7_XENLA
AccessioniPrimary (citable) accession number: A1L2T6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: April 14, 2009
Last modified: October 29, 2014
This is version 28 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3