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A1L2T6

- ZCHC7_XENLA

UniProt

A1L2T6 - ZCHC7_XENLA

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Protein
Zinc finger CCHC domain-containing protein 7
Gene
zcchc7
Organism
Xenopus laevis (African clawed frog)
Status
Reviewed - Annotation score: 2 out of 5 - Experimental evidence at transcript leveli

Functioni

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri265 – 28218CCHC-type 1
Add
BLAST
Zinc fingeri287 – 30418CCHC-type 2
Add
BLAST
Zinc fingeri305 – 32218CCHC-type 3
Add
BLAST
Zinc fingeri328 – 34518CCHC-type 4
Add
BLAST
Zinc fingeri372 – 38918CCHC-type 5
Add
BLAST

GO - Molecular functioni

  1. nucleic acid binding Source: InterPro
  2. zinc ion binding Source: InterPro
Complete GO annotation...

Keywords - Ligandi

Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Zinc finger CCHC domain-containing protein 7
Alternative name(s):
TRAMP-like complex RNA-binding factor ZCCHC7
Gene namesi
Name:zcchc7
OrganismiXenopus laevis (African clawed frog)
Taxonomic identifieri8355 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusXenopus

Organism-specific databases

XenbaseiXB-GENE-6255854. zcchc7.

Subcellular locationi

Nucleusnucleolus By similarity

GO - Cellular componenti

  1. nucleolus Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 563563Zinc finger CCHC domain-containing protein 7
PRO_0000370243Add
BLAST

Interactioni

Subunit structurei

Component of a nucleolar TRAMP-like complex, an ATP-dependent exosome regulatory complex consisting of an helicase (SKIV2L2/MTR4), an oligadenylate polymerase (PAPD5 or PAPD7), and a substrate specific RNA-binding factor (ZCCHC7 or ZCCHC8). Several TRAMP-like complexes exist with specific compositions and are associated with nuclear, or nucleolar RNA exosomes By similarity.

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Repeat, Zinc-finger

Family and domain databases

Gene3Di4.10.60.10. 4 hits.
InterProiIPR001878. Znf_CCHC.
[Graphical view]
PfamiPF00098. zf-CCHC. 1 hit.
[Graphical view]
SMARTiSM00343. ZnF_C2HC. 5 hits.
[Graphical view]
SUPFAMiSSF57756. SSF57756. 2 hits.
PROSITEiPS50158. ZF_CCHC. 3 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A1L2T6-1 [UniParc]FASTAAdd to Basket

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MFNCDEDLKA YEDELYHEET SSDESIDSEL EFHLYSQVHY SQNLSESKPE    50
EDTGGDSVTY VPGAKQQNNA CTEKDDKLVD IIILSDSDAK VSDTCPVIIL 100
SDTTEEDSVY SSKIKKKYSS TYVQGESLCG PCSHSTPKVS APQSNNFKSQ 150
KSCQNSSSKN YSGGYVQEVL VIRGSSEDEE ANKSENDIII SESDMSDVEN 200
WMLLGRAKED GDASIQLNLE GYKILSDDEG ERGAAWSISE KDVEAQIGNY 250
TPLRRSNRYY TDKNVVCRNC DKRGHLSKNC PVPKKLPACC LCGERGHYQN 300
SCPSRYCLNC FLPGHFFKEC IERAYWRKTC HRCSMPGHYA DACPEIWRQY 350
HLTIKAGPIK KPKSHSGQKD IVYCCNCAKK GHCIYECKER RMNSDKLPTC 400
QLVFSYDHEY DIRKRNERTK SKIKDFQKAG LLTCEMREFS ESKVDAKPPA 450
KKRKKKHPSK KERKGTIRDY ECAETKQKKK HKKRKSGLQE IEGDFPRGIP 500
NSYVELKKPS KKYDGSFLHL DKTKDMFKNR QKKTRRGKRC SSAVDQDLLI 550
IKQKKKKSKR KVA 563
Length:563
Mass (Da):64,410
Last modified:April 14, 2009 - v2
Checksum:i4D4C83EBFBB177D6
GO

Sequence cautioni

The sequence AAI29702.1 differs from that shown. Reason: Erroneous initiation.

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BC129701 mRNA. Translation: AAI29702.1. Different initiation.
UniGeneiXl.19467.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BC129701 mRNA. Translation: AAI29702.1 . Different initiation.
UniGenei Xl.19467.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Organism-specific databases

Xenbasei XB-GENE-6255854. zcchc7.

Family and domain databases

Gene3Di 4.10.60.10. 4 hits.
InterProi IPR001878. Znf_CCHC.
[Graphical view ]
Pfami PF00098. zf-CCHC. 1 hit.
[Graphical view ]
SMARTi SM00343. ZnF_C2HC. 5 hits.
[Graphical view ]
SUPFAMi SSF57756. SSF57756. 2 hits.
PROSITEi PS50158. ZF_CCHC. 3 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. NIH - Xenopus Gene Collection (XGC) project
    Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Thymus.

Entry informationi

Entry nameiZCHC7_XENLA
AccessioniPrimary (citable) accession number: A1L2T6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: April 14, 2009
Last modified: April 16, 2014
This is version 26 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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