ID   A1L151_MOUSE            Unreviewed;       348 AA.
AC   A1L151; Q4G0C9;
DT   06-FEB-2007, integrated into UniProtKB/TrEMBL.
DT   06-FEB-2007, sequence version 1.
DT   22-FEB-2023, entry version 103.
DE   SubName: Full=G protein-coupled receptor 37-like 1 {ECO:0000313|EMBL:AAI27620.1};
GN   Name=Gpr37l1 {ECO:0000313|EMBL:AAI27620.1,
GN   ECO:0000313|MGI:MGI:1928503};
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090 {ECO:0000313|EMBL:AAI27620.1};
RN   [1] {ECO:0000313|EMBL:AAI27620.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=CD1 {ECO:0000313|EMBL:AAH98482.2};
RC   TISSUE=Neural Stem Cell {ECO:0000313|EMBL:AAH98482.2}, and PCR rescued
RC   clones {ECO:0000313|EMBL:AAI27620.1};
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RA   Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H.,
RA   Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M.,
RA   Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.,
RA   Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F.,
RA   Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T.,
RA   Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F.,
RA   Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E.,
RA   Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y.,
RA   Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E.,
RA   Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y.,
RA   Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W.,
RA   Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J.,
RA   Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S.,
RA   Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J.,
RA   Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W.,
RA   Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J.,
RA   Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I.,
RA   Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U.,
RA   Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A.,
RA   Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC       Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
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DR   EMBL; BC098482; AAH98482.2; -; mRNA.
DR   EMBL; BC127619; AAI27620.1; -; mRNA.
DR   EMBL; BC127620; AAI27621.1; -; mRNA.
DR   RefSeq; NP_602320.2; NM_134438.3.
DR   AlphaFoldDB; A1L151; -.
DR   SwissPalm; A1L151; -.
DR   PeptideAtlas; A1L151; -.
DR   DNASU; 171469; -.
DR   GeneID; 171469; -.
DR   KEGG; mmu:171469; -.
DR   AGR; MGI:1928503; -.
DR   CTD; 9283; -.
DR   MGI; MGI:1928503; Gpr37l1.
DR   OrthoDB; 4268515at2759; -.
DR   BioGRID-ORCS; 171469; 2 hits in 77 CRISPR screens.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0004930; F:G protein-coupled receptor activity; IEA:UniProtKB-KW.
DR   CDD; cd15126; 7tmA_ETBR-LP2; 1.
DR   Gene3D; 1.20.1070.10; Rhodopsin 7-helix transmembrane proteins; 1.
DR   InterPro; IPR000276; GPCR_Rhodpsn.
DR   InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR   InterPro; IPR003909; GPR37_orph.
DR   PANTHER; PTHR46216:SF4; G-PROTEIN COUPLED RECEPTOR 37-LIKE 1; 1.
DR   PANTHER; PTHR46216; PROSAPOSIN RECEPTOR GPR37 FAMILY MEMBER; 1.
DR   Pfam; PF00001; 7tm_1; 1.
DR   PRINTS; PR00237; GPCRRHODOPSN.
DR   PRINTS; PR01421; GPR37ORPHANR.
DR   SUPFAM; SSF81321; Family A G protein-coupled receptor-like; 1.
DR   PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
PE   2: Evidence at transcript level;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW   G-protein coupled receptor {ECO:0000256|ARBA:ARBA00023040};
KW   Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Receptor {ECO:0000256|ARBA:ARBA00023170, ECO:0000313|EMBL:AAI27620.1};
KW   Signal {ECO:0000256|ARBA:ARBA00022729};
KW   Transducer {ECO:0000256|ARBA:ARBA00023224};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        36..56
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        115..137
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        177..200
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          14..283
FT                   /note="G-protein coupled receptors family 1 profile"
FT                   /evidence="ECO:0000259|PROSITE:PS50262"
SQ   SEQUENCE   348 AA;  38320 MW;  EA6436ADF11190C7 CRC64;
     MLLALVVFAV GIVGNLSVMC IVWHSYYLKS AWNSILASLA LWDFLVLFFC LPIVIFNEIT
     KQRLLGDVSC RAVPFMEVSS LGVTTFSLCA LGIDRFHVAT STLPKVRPIE RCQSILAKLA
     VIWVGSMMLA VPELLLWQLA QEPAPTAGTV DSCIMKPSAD LPESVYSLVM TYQNARMWWY
     FGCYFCLPIL FTVTCQLVTW RVRGPPGRKP ECRAGRHEQC ESQLNSTVVG LTVVYAFCTL
     PENVCNIVVA YLSTELTRQT LDLLGLINQF STFFKGAITP VLLLCICRPL GQAFLDCCCC
     CCCEECGGAS DSSATVSADS KLKAEVSSSI YFHKPRESPP LLPLGTPC
//