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Protein
Submitted name:

Teashirt zinc finger homeobox 3

Gene

TSHZ3

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingImported

Names & Taxonomyi

Protein namesi
Submitted name:
Teashirt zinc finger homeobox 3Imported
Gene namesi
Name:TSHZ3Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

Expressioni

Gene expression databases

BgeeiENSG00000121297.

Interactioni

Binary interactionsi

Show more details

Protein-protein interaction databases

IntActiA1L0U7. 15 interactors.
STRINGi9606.ENSP00000240587.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini92 – 121C2H2-typeInterPro annotationAdd BLAST30
Domaini706 – 777Homeobox DNA-bindingInterPro annotationAdd BLAST72
Domaini858 – 886C2H2-typeInterPro annotationAdd BLAST29

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili424 – 447Sequence analysisAdd BLAST24

Keywords - Domaini

Coiled coilSequence analysis, HomeoboxImported

Phylogenomic databases

eggNOGiENOG410IFDT. Eukaryota.
ENOG410XQQR. LUCA.
HOVERGENiHBG079626.

Family and domain databases

Gene3Di1.10.10.60. 1 hit.
InterProiView protein in InterPro
IPR009057. Homeobox-like.
IPR001356. Homeobox_dom.
IPR027008. Teashirt_fam.
IPR026810. Tshz3.
IPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
PANTHERiPTHR12487. PTHR12487. 1 hit.
PTHR12487:SF9. PTHR12487:SF9. 1 hit.
PfamiView protein in Pfam
PF13912. zf-C2H2_6. 1 hit.
SMARTiView protein in SMART
SM00389. HOX. 1 hit.
SM00355. ZnF_C2H2. 5 hits.
SUPFAMiSSF46689. SSF46689. 1 hit.
PROSITEiView protein in PROSITE
PS50071. HOMEOBOX_2. 1 hit.
PS00028. ZINC_FINGER_C2H2_1. 4 hits.
PS50157. ZINC_FINGER_C2H2_2. 2 hits.

Sequencei

Sequence statusi: Complete.

A1L0U7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLPEPSLFST VQLYRQSSKL YGSIFTGASK FRCKDCSAAY DTLVELTVHM
60 70 80 90 100
NETGHYRDDN HETDNNNPKR WSKPRKRSLL EMEGKEDAQK VLKCMYCGHS
110 120 130 140 150
FESLQDLSVH MIKTKHYQKV PLKEPVTPVA AKIIPATRKK ASLELELPSS
160 170 180 190 200
PDSTGGTPKA TISDTNDALQ KNSNPYITPN NRYGHQNGAS YAWHFEARKS
210 220 230 240 250
QILKCMECGS SHDTLQELTA HMMVTGHFIK VTNSAMKKGK PIVETPVTPT
260 270 280 290 300
ITTLLDEKVQ SVPLAATTFT SPSNTPASIS PKLNVEVKKE VDKEKAVTDE
310 320 330 340 350
KPKQKDKPGE EEEKCDISSK YHYLTENDLE ESPKGGLDIL KSLENTVTSA
360 370 380 390 400
INKAQNGTPS WGGYPSIHAA YQLPNMMKLS LGSSGKSTPL KPMFGNSEIV
410 420 430 440 450
SPTKNQTLVS PPSSQTSPMP KTNFHAMEEL VKKVTEKVAK VEEKMKEPDG
460 470 480 490 500
KLSPPKRATP SPCSSEVGEP IKMEASSDGG FRSQENSPSP PRDGCKDGSP
510 520 530 540 550
LAEPVENGKE LVKPLASSLS GSTAIITDHP PEQPFVNPLS ALQSVMNIHL
560 570 580 590 600
GKAAKPSLPA LDPMSMLFKM SNSLAEKAAV ATPPPLQSKK ADHLDRYFYH
610 620 630 640 650
VNNDQPIDLT KGKSDKGCSL GSVLLSPTST APATSSSTVT TAKTSAVVSF
660 670 680 690 700
MSNSPLRENA LSDISDMLKN LTESHTSKSS TPSSISEKSD IDGATLEEAE
710 720 730 740 750
ESTPAQKRKG RQSNWNPQHL LILQAQFAAS LRQTSEGKYI MSDLSPQERM
760 770 780 790 800
HISRFTGLSM TTISHWLANV KYQLRRTGGT KFLKNLDTGH PVFFCNDCAS
810 820 830 840 850
QIRTPSTYIS HLESHLGFRL RDLSKLSTEQ INSQIAQTKS PSEKMVTSSP
860 870 880 890
EEDLGTSYQC KLCNRTFASK HAVKLHLSKT HGKSPEDHLL YVSELEKQ
Length:898
Mass (Da):98,486
Last modified:February 6, 2007 - v1
Checksum:i14BB8B998CEDE55D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC127095 mRNA. Translation: AAI27096.1.
BC127096 mRNA. Translation: AAI27097.1.
UniGeneiHs.278436.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC127095 mRNA. Translation: AAI27096.1.
BC127096 mRNA. Translation: AAI27097.1.
UniGeneiHs.278436.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiA1L0U7. 15 interactors.
STRINGi9606.ENSP00000240587.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

eggNOGiENOG410IFDT. Eukaryota.
ENOG410XQQR. LUCA.
HOVERGENiHBG079626.

Miscellaneous databases

ChiTaRSiTSHZ3. human.

Gene expression databases

BgeeiENSG00000121297.

Family and domain databases

Gene3Di1.10.10.60. 1 hit.
InterProiView protein in InterPro
IPR009057. Homeobox-like.
IPR001356. Homeobox_dom.
IPR027008. Teashirt_fam.
IPR026810. Tshz3.
IPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
PANTHERiPTHR12487. PTHR12487. 1 hit.
PTHR12487:SF9. PTHR12487:SF9. 1 hit.
PfamiView protein in Pfam
PF13912. zf-C2H2_6. 1 hit.
SMARTiView protein in SMART
SM00389. HOX. 1 hit.
SM00355. ZnF_C2H2. 5 hits.
SUPFAMiSSF46689. SSF46689. 1 hit.
PROSITEiView protein in PROSITE
PS50071. HOMEOBOX_2. 1 hit.
PS00028. ZINC_FINGER_C2H2_1. 4 hits.
PS50157. ZINC_FINGER_C2H2_2. 2 hits.
ProtoNetiSearch...

Entry informationi

Entry nameiA1L0U7_HUMAN
AccessioniPrimary (citable) accession number: A1L0U7
Entry historyiIntegrated into UniProtKB/TrEMBL: February 6, 2007
Last sequence update: February 6, 2007
Last modified: February 15, 2017
This is version 88 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.