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Protein

Tropomyosin

Gene

TM1

Organism
Penaeus monodon (Giant tiger prawn)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Tropomyosin, in association with the troponin complex, plays a central role in the calcium dependent regulation of muscle contraction.By similarity

Names & Taxonomyi

Protein namesi
Recommended name:
Tropomyosin1 PublicationImported
Alternative name(s):
Tropomyosin, fast isoform1 PublicationImported
Short name:
Tm-Penm-fastImported
Gene namesi
Name:TM1By similarity
OrganismiPenaeus monodon (Giant tiger prawn)
Taxonomic identifieri6687 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaCrustaceaMalacostracaEumalacostracaEucaridaDecapodaDendrobranchiataPenaeoideaPenaeidaePenaeus

Pathology & Biotechi

Allergenic propertiesi

Causes an allergic reaction in human.2 Publications

Keywords - Diseasei

Allergen

Protein family/group databases

Allergomei3410 Pen m 1.0101
972 Pen m 1

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003987881 – 284TropomyosinAdd BLAST284

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei1N-acetylmethionine1 Publication1

Keywords - PTMi

Acetylation

Proteomic databases

PRIDEiA1KYZ2

Interactioni

Subunit structurei

Homodimer.By similarity

Structurei

3D structure databases

ProteinModelPortaliA1KYZ2
SMRiA1KYZ2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili1 – 284By similarityAdd BLAST284

Domaini

The molecule is in a coiled coil structure that is formed by 2 polypeptide chains. The sequence exhibits a prominent seven-residues periodicity.Curated

Sequence similaritiesi

Belongs to the tropomyosin family.Sequence analysis

Keywords - Domaini

Coiled coil, Repeat

Family and domain databases

InterProiView protein in InterPro
IPR000533 Tropomyosin
PfamiView protein in Pfam
PF00261 Tropomyosin, 1 hit
PRINTSiPR00194 TROPOMYOSIN
PROSITEiView protein in PROSITE
PS00326 TROPOMYOSIN, 1 hit

Sequencei

Sequence statusi: Complete.

A1KYZ2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDAIKKKMQA MKLEKDNAMD RADTLEQQNK EANNRAEKSE EEVHNLQKRM
60 70 80 90 100
QQLENDLDQV QESLLKANIQ LVEKDKALSN AEGEVAALNR RIQLLEEDLE
110 120 130 140 150
RSEERLNTAT TKLAEASQAA DESERMRKVL ENRSLSDEER MDALENQLKE
160 170 180 190 200
ARFLAEEADR KYDEVARKLA MVEADLERAE ERAETGESKI VELEEELRVV
210 220 230 240 250
GNNLKSLEVS EEKANQREEA YKEQIKTLTN KLKAAEARAE FAERSVQKLQ
260 270 280
KEVDRLEDEL VNEKEKYKSI TDELDQTFSE LSGY
Length:284
Mass (Da):32,849
Last modified:February 6, 2007 - v1
Checksum:iBE53B602C37E85E2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY827100 mRNA Translation: AAX37288.1
AB270629 mRNA Translation: BAF47262.1

Similar proteinsi

Entry informationi

Entry nameiTPM_PENMO
AccessioniPrimary (citable) accession number: A1KYZ2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 5, 2010
Last sequence update: February 6, 2007
Last modified: May 23, 2018
This is version 33 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

Direct protein sequencing
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Main funding by: National Institutes of Health