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A1KWE0

- CAPP_NEIMF

UniProt

A1KWE0 - CAPP_NEIMF

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Protein
Phosphoenolpyruvate carboxylase
Gene
ppc, NMC2042
Organism
Neisseria meningitidis serogroup C / serotype 2a (strain ATCC 700532 / DSM 15464 / FAM18)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle By similarity.UniRule annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotation

Cofactori

Magnesium By similarity.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei140 – 1401 By similarity
Active sitei568 – 5681 By similarity

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP
Complete GO annotation...

GO - Biological processi

  1. carbon fixation Source: UniProtKB-HAMAP
  2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
  3. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Lyase

Keywords - Biological processi

Carbon dioxide fixation

Keywords - Ligandi

Magnesium

Enzyme and pathway databases

BioCyciNMEN272831:GJDX-1939-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylase (EC:4.1.1.31)
Short name:
PEPC
Short name:
PEPCase
Gene namesi
Name:ppc
Ordered Locus Names:NMC2042
OrganismiNeisseria meningitidis serogroup C / serotype 2a (strain ATCC 700532 / DSM 15464 / FAM18)
Taxonomic identifieri272831 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaNeisserialesNeisseriaceaeNeisseria
ProteomesiUP000002286: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 900900Phosphoenolpyruvate carboxylaseUniRule annotation
PRO_1000025568Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi272831.NMC2042.

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.

Phylogenomic databases

eggNOGiCOG2352.
HOGENOMiHOG000238647.
KOiK01595.
OMAiELSTISC.
OrthoDBiEOG6TJ7T8.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A1KWE0-1 [UniParc]FASTAAdd to Basket

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MQLHILNNPK DAALAADAEF LKQSLFNLLH EEASPLVVET VKLLSTSDDS    50
AALIEKVLPQ LDEQQTHDLT LACGLFAQIL NIAEDVHHER RRQIHEEAGR 100
GGAEGSLTET VRRLKAGKAD GKSVQRQLDN TSVTAVLTAH PTEVQRQTVL 150
SFNRRIRALL PQRERCTNAD ALARLRREID TILLGLWQTS ETRRHKLSVN 200
DEINNGVSIF PMSFFEALPK LYRNMEHDFQ MVYPDVCVPN ILKIGGWIGG 250
DRDGNPFVSA ETLRFAFRRH ADAVFRFYRG ELDKLYRELP LSIRRVKVND 300
DVMALAALSP DEELARTEEP YRRAIAYIMA RAMGKARALG LGMGCKFGFL 350
EPYASAQEFL DDLKKLQRSL IDNGSRLLAE GRLADLIRSV SVFGFHMMPL 400
DLRQHAGKHA DVVAELFQHA GLEDYNSLNE EQKQAVLLRE LSHQRPLYSP 450
FITYSDHTRH ELAIFNEARK IKDEFGEDAV TQSIISNCEQ PSDLLALALL 500
LKESGLLAVE NGKPHSRINI VPLFETIEAL ENACPVMETM FRLDWYDALL 550
ESRGNIQEIM LGYSDSNKDG GYVTSSWCLY QAELGLVELF KKYDVRMRLF 600
HGRGGSVGRG GGPSYQAILA QPAGSVAGQI RITEQGEVIT AKYADPGNAQ 650
RNLETLVAAT LEASILPDKK DPDAKLMQAL SDVSFKYYRE LITHPDFIDY 700
FLQTSPIQEI ATLNLGSRPA SRKTLARIQD LRAIPWVFSW MQNRLMLPAW 750
YGFGSAVETL CEGNPDTLTA LREHAQSNPF FQAMLSNMEQ VMAKTDITLA 800
ENYAGLSESP DKAKIIFGMI KEEYRRSRKA LLDLLQTEEL LRDNRSLARS 850
LALRIPYLNA LNGLQVAMLK RLRKEPDNPH ALLMVHLTIN GVAQGLRNTG 900
Length:900
Mass (Da):101,160
Last modified:February 6, 2007 - v1
Checksum:i67602FA07423EF9C
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AM421808 Genomic DNA. Translation: CAM11197.1.
RefSeqiYP_975964.1. NC_008767.1.

Genome annotation databases

EnsemblBacteriaiCAM11197; CAM11197; NMC2042.
GeneIDi4676522.
KEGGinmc:NMC2042.
PATRICi20354660. VBINeiMen17609_2552.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AM421808 Genomic DNA. Translation: CAM11197.1 .
RefSeqi YP_975964.1. NC_008767.1.

3D structure databases

ModBasei Search...

Protein-protein interaction databases

STRINGi 272831.NMC2042.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAM11197 ; CAM11197 ; NMC2042 .
GeneIDi 4676522.
KEGGi nmc:NMC2042.
PATRICi 20354660. VBINeiMen17609_2552.

Phylogenomic databases

eggNOGi COG2352.
HOGENOMi HOG000238647.
KOi K01595.
OMAi ELSTISC.
OrthoDBi EOG6TJ7T8.

Enzyme and pathway databases

BioCyci NMEN272831:GJDX-1939-MONOMER.

Family and domain databases

HAMAPi MF_00595. PEPcase_type1.
InterProi IPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view ]
Pfami PF00311. PEPcase. 1 hit.
[Graphical view ]
PRINTSi PR00150. PEPCARBXLASE.
SUPFAMi SSF51621. SSF51621. 1 hit.
PROSITEi PS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 700532 / DSM 15464 / FAM18.

Entry informationi

Entry nameiCAPP_NEIMF
AccessioniPrimary (citable) accession number: A1KWE0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: February 6, 2007
Last modified: May 14, 2014
This is version 54 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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