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A1KUU3 (A1KUU3_NEIMF) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 42. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Nicotinate phosphoribosyltransferase HAMAP MF_00570
Short name=NAPRTase HAMAP MF_00570
EC=2.4.2.11 HAMAP MF_00570
Gene names
Name:pncB HAMAP MF_00570 EMBL CAM10642.1
Ordered Locus Names:NMC1435
OrganismNeisseria meningitidis serogroup C / serotype 2a (strain ATCC 700532 / FAM18) [Complete proteome] [HAMAP]
Taxonomic identifier272831 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Betaproteobacteria › Neisseriales › Neisseriaceae › Neisseria

Protein attributes

Sequence length419 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Nicotinate D-ribonucleotide + diphosphate = nicotinate + 5-phospho-alpha-D-ribose 1-diphosphate. HAMAP MF_00570 RuleBase RU003838 SAAS SAAS002638

Pathway

Cofactor biosynthesis; NAD(+) biosynthesis; nicotinate D-ribonucleotide from nicotinate: step 1/1. HAMAP MF_00570 SAAS SAAS002638

Cofactor biosynthesis; NAD(+) biosynthesis; nicotinate ribonucleotide from nicotinate: step 1/1. RuleBase RU003838

Subcellular location

Cytoplasm By similarity HAMAP MF_00570 SAAS SAAS002638.

Sequence similarities

Belongs to the NAPRTase family. HAMAP MF_00570 RuleBase RU003838

Sequences

Sequence LengthMass (Da)Tools
A1KUU3 [UniParc].

Last modified February 6, 2007. Version 1.
Checksum: 39AD26013245034E

FASTA41948,253
        10         20         30         40         50         60 
MCSNTPQAAT KNRETRHMTG IIHSLLDTDL YKFTMLQVVL HQFPQTHSLY EFRCRNASTV 

        70         80         90        100        110        120 
YPLADIKEDL EAELDALCRL RFTHDELGYL RSLRFIKSDF VDYLELFQLQ RRFVEIGTDD 

       130        140        150        160        170        180 
KDRLNIRIEG PMIQAMFFEI FILAIVNELY FRRLETPAVI EEGERRLQAK AARLKEIAAA 

       190        200        210        220        230        240 
QNPDDPPFLI SDFGTRRRYK LAWQEHVIRT LLEAAPSIVR GTSNVFLAKK LGITPIGTMA 

       250        260        270        280        290        300 
HEFLQAFQAL DVRLRNFQKA ALESWVHEYR GDLGVALTDV VGMDAFLRDF DLYFAKLFDG 

       310        320        330        340        350        360 
LRHDSGDPYV WGDKAYAHYQ KLKIDSRTKM LTFSDGLDIE RSWALHQYFK DRFKTGFGIG 

       370        380        390        400        410 
TNLTNDMGHT PLNIVLKLVE CNGQSVAKLS DSPGKTMTNN STFLAYLRQV FDVPEPETP

« Hide

References

[1]"Meningococcal genetic variation mechanisms viewed through comparative analysis of serogroup C strain FAM18."
Bentley S.D., Vernikos G.S., Snyder L.A.S., Churcher C., Arrowsmith C., Chillingworth T., Cronin A., Davis P.H., Holroyd N.E., Jagels K., Maddison M., Moule S., Rabbinowitsch E., Sharp S., Unwin L., Whitehead S., Quail M.A., Achtman M. expand/collapse author list , Barrell B.G., Saunders N.J., Parkhill J.
PLoS Genet. 3:230-240(2007) [PubMed: 17305430] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AM421808 Genomic DNA. Translation: CAM10642.1.
RefSeqYP_975422.1. NC_008767.1.

3D structure databases

ProteinModelPortalA1KUU3.
ModBaseSearch...

Protein-protein interaction databases

STRINGA1KUU3.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBNEIT00000007206; EBNEIP00000006975; EBNEIG00000007206.
GeneID4675561.
GenomeReviewsGene locus NMC1435 in contig AM421808_GR.
KEGGnmc:NMC1435.
NMPDRfig|487.2.peg.995.
PATRIC20353020. VBINeiMen17609_1755.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1488.
GeneTreeEBGT00050000021580.
HOGENOMHBG325503.
OMAHQFPQTH.
PhylomeDBA1KUU3.
ProtClustDBPRK05321.

Family and domain databases

HAMAPMF_00570. NAPRTase.
[Tree]
InterProIPR006406. Nic_PRibTrfase.
IPR015977. Nic_PRibTrfase-like.
IPR007229. Nic_PRibTrfase-rel.
IPR002638. Quinolinate_PRibosylTrfase_C.
[Graphical view]
KOK00763.
PfamPF04095. NAPRTase. 1 hit.
[Graphical view]
PIRSFPIRSF000484. NAPRT. 1 hit.
SUPFAMSSF51690. Q_phspho_trans. 1 hit.
TIGRFAMsTIGR01514. NAPRTase. 1 hit.
ProtoNetSearch...

Entry information

Entry nameA1KUU3_NEIMF
AccessionPrimary (citable) accession number: A1KUU3
Entry history
Integrated into UniProtKB/TrEMBL: February 6, 2007
Last sequence update: February 6, 2007
Last modified: December 14, 2011
This is version 42 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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